JP2024500512A5 - - Google Patents
Info
- Publication number
- JP2024500512A5 JP2024500512A5 JP2023539061A JP2023539061A JP2024500512A5 JP 2024500512 A5 JP2024500512 A5 JP 2024500512A5 JP 2023539061 A JP2023539061 A JP 2023539061A JP 2023539061 A JP2023539061 A JP 2023539061A JP 2024500512 A5 JP2024500512 A5 JP 2024500512A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- sequence shown
- seq
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011544445 | 2020-12-23 | ||
| CN202011544445.8 | 2020-12-23 | ||
| PCT/CN2021/140449 WO2022135467A1 (zh) | 2020-12-23 | 2021-12-22 | 抗b7-h3抗体及其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500512A JP2024500512A (ja) | 2024-01-09 |
| JP2024500512A5 true JP2024500512A5 (https=) | 2025-01-07 |
Family
ID=82157408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023539061A Pending JP2024500512A (ja) | 2020-12-23 | 2021-12-22 | 抗ｂ７－ｈ３抗体およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240043540A1 (https=) |
| EP (1) | EP4269435A4 (https=) |
| JP (1) | JP2024500512A (https=) |
| KR (1) | KR20230124959A (https=) |
| CN (1) | CN117098548A (https=) |
| AU (1) | AU2021407023B2 (https=) |
| CA (1) | CA3203257A1 (https=) |
| WO (1) | WO2022135467A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119948063A (zh) * | 2022-06-23 | 2025-05-06 | 信达生物制药(苏州)有限公司 | 结合egfr和b7-h3的双特异性抗体 |
| WO2024007129A1 (zh) * | 2022-07-04 | 2024-01-11 | 英诺湖医药(杭州)有限公司 | 人源化的b7h3抗体或其抗原结合片段 |
| CN119925631A (zh) * | 2023-11-03 | 2025-05-06 | 信达生物制药(苏州)有限公司 | 靶向b7-h3的抗体-药物偶联物及其用途 |
| WO2025131054A1 (en) * | 2023-12-22 | 2025-06-26 | Innovent Biologics (Suzhou) Co., Ltd. | Antibody drug conjugates targeting to b7-h3 and egfr and the use thereof |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| ATE375365T1 (de) | 1998-04-02 | 2007-10-15 | Genentech Inc | Antikörper varianten und fragmente davon |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PL209392B1 (pl) | 1999-01-15 | 2011-08-31 | Genentech Inc | Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała |
| TWI335821B (en) | 2002-12-16 | 2011-01-11 | Genentech Inc | Immunoglobulin variants and uses thereof |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| US8227577B2 (en) | 2007-12-21 | 2012-07-24 | Hoffman-La Roche Inc. | Bivalent, bispecific antibodies |
| US8242247B2 (en) | 2007-12-21 | 2012-08-14 | Hoffmann-La Roche Inc. | Bivalent, bispecific antibodies |
| US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| CA2756244A1 (en) | 2009-04-02 | 2010-10-07 | Roche Glycart Ag | Multispecific antibodies comprising full length antibodies and single chain fab fragments |
| SG175077A1 (en) | 2009-04-07 | 2011-11-28 | Roche Glycart Ag | Trivalent, bispecific antibodies |
| PE20120540A1 (es) | 2009-05-27 | 2012-05-09 | Hoffmann La Roche | Anticuerpos triespecificos o tetraespecificos |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
| US8703132B2 (en) | 2009-06-18 | 2014-04-22 | Hoffmann-La Roche, Inc. | Bispecific, tetravalent antigen binding proteins |
| PH12012501751A1 (en) * | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| EP2542256B1 (en) * | 2010-03-04 | 2019-05-22 | MacroGenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| WO2012147713A1 (ja) * | 2011-04-25 | 2012-11-01 | 第一三共株式会社 | 抗ｂ７－ｈ３抗体 |
| KR102485788B1 (ko) * | 2014-08-27 | 2023-01-09 | 메모리얼 슬로안 케터링 캔서 센터 | 항체, 조성물 및 용도 |
| US10865245B2 (en) * | 2014-12-23 | 2020-12-15 | Full Spectrum Genetics, Inc. | Anti-B7H3 binding compounds and uses thereof |
| AU2017279550A1 (en) * | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-B7-H3 antibodies and antibody drug conjugates |
| CN109843927B (zh) * | 2017-03-06 | 2022-06-21 | 江苏恒瑞医药股份有限公司 | 抗b7-h3抗体、其抗原结合片段及其医药用途 |
| CN109963591B (zh) * | 2017-08-04 | 2023-04-04 | 江苏恒瑞医药股份有限公司 | B7h3抗体-药物偶联物及其医药用途 |
| CN109851673B (zh) * | 2019-01-22 | 2023-07-25 | 苏州旭光科星抗体生物科技有限公司 | 一种抗人b7-h3单克隆抗体的制备方法及其免疫组化检测方法及其应用及其试剂盒 |
| CN111944050B (zh) * | 2020-08-19 | 2022-05-13 | 苏州普乐康医药科技有限公司 | 一种抗b7-h3抗体及其应用 |
-
2021
- 2021-12-22 KR KR1020237023796A patent/KR20230124959A/ko active Pending
- 2021-12-22 AU AU2021407023A patent/AU2021407023B2/en active Active
- 2021-12-22 EP EP21909462.0A patent/EP4269435A4/en active Pending
- 2021-12-22 JP JP2023539061A patent/JP2024500512A/ja active Pending
- 2021-12-22 CA CA3203257A patent/CA3203257A1/en active Pending
- 2021-12-22 WO PCT/CN2021/140449 patent/WO2022135467A1/zh not_active Ceased
- 2021-12-22 CN CN202180086116.XA patent/CN117098548A/zh active Pending
- 2021-12-22 US US18/258,576 patent/US20240043540A1/en active Pending
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