JP2021531311A5 - - Google Patents
Info
- Publication number
- JP2021531311A5 JP2021531311A5 JP2021504235A JP2021504235A JP2021531311A5 JP 2021531311 A5 JP2021531311 A5 JP 2021531311A5 JP 2021504235 A JP2021504235 A JP 2021504235A JP 2021504235 A JP2021504235 A JP 2021504235A JP 2021531311 A5 JP2021531311 A5 JP 2021531311A5
- Authority
- JP
- Japan
- Prior art keywords
- membered
- alkyl
- cycloalkyl
- aryl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018096781 | 2018-07-24 | ||
| CNPCT/CN2018/096781 | 2018-07-24 | ||
| PCT/US2019/043112 WO2020023551A1 (en) | 2018-07-24 | 2019-07-23 | Naphthyridine compounds and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021531311A JP2021531311A (ja) | 2021-11-18 |
| JP2021531311A5 true JP2021531311A5 (enExample) | 2022-07-22 |
| JP7386842B2 JP7386842B2 (ja) | 2023-11-27 |
Family
ID=67551416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504235A Active JP7386842B2 (ja) | 2018-07-24 | 2019-07-23 | ナフチリジン化合物およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12297210B2 (enExample) |
| EP (1) | EP3826721B1 (enExample) |
| JP (1) | JP7386842B2 (enExample) |
| CN (1) | CN112533677A (enExample) |
| TW (1) | TW202012405A (enExample) |
| WO (1) | WO2020023551A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020069402A1 (en) * | 2018-09-30 | 2020-04-02 | Genentech, Inc. | Cinnoline compounds and for the treatment of hpk1-dependent disorders such as cancer |
| EP3873608A1 (en) | 2018-10-31 | 2021-09-08 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity |
| EP4371987B9 (en) | 2018-10-31 | 2025-11-26 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds as hpk1 inhibitors |
| US11453681B2 (en) | 2019-05-23 | 2022-09-27 | Gilead Sciences, Inc. | Substituted eneoxindoles and uses thereof |
| EP4090663A1 (en) | 2020-01-15 | 2022-11-23 | Blueprint Medicines Corporation | Map4k1 inhibitors |
| CN116456985A (zh) * | 2020-09-23 | 2023-07-18 | 深圳市原力生命科学有限公司 | 作为hpk1调节剂的嘧啶及吡啶衍生物和其使用方法 |
| CN114907375B (zh) * | 2021-02-07 | 2026-03-31 | 苏州信诺维医药科技股份有限公司 | 杂环化合物、其制备方法、药物组合物及应用 |
| CN114907374B (zh) * | 2021-02-07 | 2026-03-10 | 苏州信诺维医药科技股份有限公司 | 杂环化合物、其制备方法、药物组合物及应用 |
| MX2024000751A (es) * | 2021-07-14 | 2024-03-25 | Blueprint Medicines Corp | Compuestos heterociclicos como inhibidores de map4k1. |
| US20240336630A1 (en) * | 2021-07-15 | 2024-10-10 | Blueprint Medicines Corporation | Map4k1 inhibitors |
| WO2023001794A1 (en) | 2021-07-20 | 2023-01-26 | Astrazeneca Ab | Substituted pyrazine-2-carboxamides as hpk1 inhibitors for the treatment of cancer |
| EP4554680A1 (en) | 2022-07-15 | 2025-05-21 | Arcus Biosciences, Inc. | Inhibitors of hpk1 and methods of use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| KR101704734B1 (ko) | 2005-07-01 | 2017-02-09 | 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. | 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체 |
| CN101821279A (zh) | 2007-08-15 | 2010-09-01 | 赛特凯恩蒂克公司 | 某些化学个体、组合物和方法 |
| WO2010098788A2 (en) | 2008-08-25 | 2010-09-02 | Amplimmune, Inc. | Pd-i antagonists and methods for treating infectious disease |
| MX356367B (es) | 2008-12-09 | 2018-05-25 | Genentech Inc | Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t. |
| EP2504028A4 (en) | 2009-11-24 | 2014-04-09 | Amplimmune Inc | SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2 |
| EP3279215B1 (en) | 2009-11-24 | 2020-02-12 | MedImmune Limited | Targeted binding agents against b7-h1 |
| EP2770998B1 (en) | 2011-10-27 | 2020-04-29 | Merck Sharp & Dohme Corp. | Factor ixa inhibitors |
| RS61919B1 (sr) | 2015-06-25 | 2021-06-30 | Univ Health Network | Inhibitori hpk1 i postupci za njihovo korišćenje |
| US20180072718A1 (en) * | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11180482B2 (en) | 2016-11-30 | 2021-11-23 | Ariad Pharmaceuticals, Inc. | Anilinopyrimidines as haematopoietic progenitor kinase 1 (HPK1) inhibitors |
| CN110678466B (zh) * | 2017-03-30 | 2023-01-31 | 豪夫迈·罗氏有限公司 | 作为hpk1抑制剂的二氮杂萘类 |
-
2019
- 2019-07-23 JP JP2021504235A patent/JP7386842B2/ja active Active
- 2019-07-23 TW TW108126069A patent/TW202012405A/zh unknown
- 2019-07-23 CN CN201980049189.4A patent/CN112533677A/zh active Pending
- 2019-07-23 EP EP19750197.6A patent/EP3826721B1/en active Active
- 2019-07-23 WO PCT/US2019/043112 patent/WO2020023551A1/en not_active Ceased
-
2021
- 2021-01-22 US US17/156,384 patent/US12297210B2/en active Active