JP2021531255A5 - - Google Patents

Info

Publication number
JP2021531255A5
JP2021531255A5 JP2021500442A JP2021500442A JP2021531255A5 JP 2021531255 A5 JP2021531255 A5 JP 2021531255A5 JP 2021500442 A JP2021500442 A JP 2021500442A JP 2021500442 A JP2021500442 A JP 2021500442A JP 2021531255 A5 JP2021531255 A5 JP 2021531255A5
Authority
JP
Japan
Prior art keywords
antigen
binding fragment
monoclonal antibody
antibody
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021500442A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021531255A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/043108 external-priority patent/WO2020023548A1/en
Publication of JP2021531255A publication Critical patent/JP2021531255A/ja
Publication of JP2021531255A5 publication Critical patent/JP2021531255A5/ja
Pending legal-status Critical Current

Links

JP2021500442A 2018-07-23 2019-07-23 非古典的hla−iおよびネオアンチゲンを含む複合体を標的とする抗体、およびその使用方法 Pending JP2021531255A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862702143P 2018-07-23 2018-07-23
US62/702,143 2018-07-23
PCT/US2019/043108 WO2020023548A1 (en) 2018-07-23 2019-07-23 Antibodies targeting a complex comprising non-classical hla-i and neoantigen and their methods of use

Publications (2)

Publication Number Publication Date
JP2021531255A JP2021531255A (ja) 2021-11-18
JP2021531255A5 true JP2021531255A5 (enExample) 2022-08-01

Family

ID=69181238

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021500442A Pending JP2021531255A (ja) 2018-07-23 2019-07-23 非古典的hla−iおよびネオアンチゲンを含む複合体を標的とする抗体、およびその使用方法

Country Status (6)

Country Link
US (1) US20210253713A1 (enExample)
EP (1) EP3827021A4 (enExample)
JP (1) JP2021531255A (enExample)
AU (1) AU2019309948A1 (enExample)
CA (1) CA3107001A1 (enExample)
WO (1) WO2020023548A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11118215B2 (en) 2003-09-18 2021-09-14 Nuevolution A/S Method for obtaining structural information concerning an encoded molecule and method for selecting compounds
CA3183756A1 (en) 2020-05-19 2021-11-25 Amgen Inc. Mageb2 binding constructs
US10981997B1 (en) 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US10981996B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US11976120B2 (en) * 2020-06-01 2024-05-07 Boehringer Ingelheim International Gmbh Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US20250051454A1 (en) * 2020-09-15 2025-02-13 Duke University Antibodies that target hla-e-host peptide complexes and uses thereof
EP4388012A4 (en) * 2021-08-20 2025-09-17 Univ Duke ANTIBODIES TARGETING HLA-E-HOST PEPTIDE COMPLEXES AND THEIR USES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1790664A1 (en) * 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
PE20090321A1 (es) * 2007-06-04 2009-04-20 Genentech Inc Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
EP2699603B1 (en) * 2011-04-19 2016-03-02 The United States of America As Represented by the Secretary Department of Health and Human Services Human monoclonal antibodies specific for glypican-3 and use thereof
US10656156B2 (en) * 2012-07-05 2020-05-19 Mepur Ravindranath Diagnostic and therapeutic potential of HLA-E monospecific monoclonal IgG antibodies directed against tumor cell surface and soluble HLA-E
US10329348B2 (en) * 2014-10-23 2019-06-25 Innate Pharma Treatment of cancers using anti-NKG2A agents
EP3475706B1 (en) * 2016-06-27 2021-08-11 Juno Therapeutics, Inc. Mhc-e restricted epitopes, binding molecules and related methods and uses
EP3573997A4 (en) * 2017-01-24 2020-12-09 Abexxa Biologics, Inc. METHODS AND COMPOSITIONS INTENDED TO TARGE A COMPLEX INCLUDING A NON-CLASSIC HLA-I AND A NEO-ANTIGEN IN THE TREATMENT OF CANCER
US10981997B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US10981996B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US11976120B2 (en) * 2020-06-01 2024-05-07 Boehringer Ingelheim International Gmbh Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use

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