JP2021530244A5 - - Google Patents

Info

Publication number
JP2021530244A5
JP2021530244A5 JP2021503901A JP2021503901A JP2021530244A5 JP 2021530244 A5 JP2021530244 A5 JP 2021530244A5 JP 2021503901 A JP2021503901 A JP 2021503901A JP 2021503901 A JP2021503901 A JP 2021503901A JP 2021530244 A5 JP2021530244 A5 JP 2021530244A5
Authority
JP
Japan
Prior art keywords
antigen
antibody
binding fragment
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021503901A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021530244A (ja
JP7525471B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/043254 external-priority patent/WO2020023644A2/en
Publication of JP2021530244A publication Critical patent/JP2021530244A/ja
Publication of JP2021530244A5 publication Critical patent/JP2021530244A5/ja
Priority to JP2024053871A priority Critical patent/JP2024105229A/ja
Application granted granted Critical
Publication of JP7525471B2 publication Critical patent/JP7525471B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021503901A 2018-07-24 2019-07-24 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体 Active JP7525471B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024053871A JP2024105229A (ja) 2018-07-24 2024-03-28 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862702762P 2018-07-24 2018-07-24
US62/702,762 2018-07-24
PCT/US2019/043254 WO2020023644A2 (en) 2018-07-24 2019-07-24 Antibody directed against s. aureus clumping factor a (clfa)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024053871A Division JP2024105229A (ja) 2018-07-24 2024-03-28 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体

Publications (3)

Publication Number Publication Date
JP2021530244A JP2021530244A (ja) 2021-11-11
JP2021530244A5 true JP2021530244A5 (enExample) 2022-08-01
JP7525471B2 JP7525471B2 (ja) 2024-07-30

Family

ID=67539640

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021503901A Active JP7525471B2 (ja) 2018-07-24 2019-07-24 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体
JP2024053871A Pending JP2024105229A (ja) 2018-07-24 2024-03-28 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024053871A Pending JP2024105229A (ja) 2018-07-24 2024-03-28 S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体

Country Status (10)

Country Link
US (3) US11155606B2 (enExample)
EP (1) EP3840838A2 (enExample)
JP (2) JP7525471B2 (enExample)
CN (2) CN119176871A (enExample)
AU (1) AU2019309366B2 (enExample)
BR (1) BR112021001214A2 (enExample)
CA (1) CA3107463A1 (enExample)
MX (1) MX2021000889A (enExample)
TW (1) TWI902669B (enExample)
WO (1) WO2020023644A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015010125A2 (pt) 2012-11-06 2017-08-22 Medimmune Llc Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente
DE102018115012A1 (de) 2018-06-21 2019-12-24 Carl Zeiss Microscopy Gmbh Teilchenstrahlsystem
JP7525471B2 (ja) 2018-07-24 2024-07-30 メディミューン,エルエルシー S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体
TWI895248B (zh) 2018-10-09 2025-09-01 美商麥迪紐有限責任公司 針對金黃色葡萄球菌白血球毒素的抗體
BR112021006622A2 (pt) 2018-10-09 2021-07-20 Medimmune, Llc combinações de anticorpos anti-staphylococcus aureus
TWI743626B (zh) 2019-01-24 2021-10-21 德商卡爾蔡司多重掃描電子顯微鏡有限公司 包含多束粒子顯微鏡的系統、對3d樣本逐層成像之方法及電腦程式產品
DE102019008249B3 (de) 2019-11-27 2020-11-19 Carl Zeiss Multisem Gmbh Teilchenstrahl-System mit einer Multistrahl-Ablenkeinrichtung und einem Strahlfänger, Verfahren zum Betreiben des Teilchenstrahl-Systems und zugehöriges Computerprogrammprodukt
WO2024231440A1 (en) * 2023-05-09 2024-11-14 Astrazeneca Ab Bispecific anti-pseudomonas antibodies with modified fc regions and methods of use thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
US7658921B2 (en) 2000-12-12 2010-02-09 Medimmune, Llc Molecules with extended half-lives, compositions and uses thereof
PT1377314E (pt) 2001-01-26 2012-01-02 Inhibitex Inc Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções
MXPA05000511A (es) 2001-07-12 2005-09-30 Jefferson Foote Anticuepros super humanizados.
US20030226155A1 (en) 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
ATE458006T1 (de) 2003-05-14 2010-03-15 Kenta Biotech Ag Humaner monoklonaler antikörper spezifisch für lipopolysacchariden (lps) des serotyps iats o6 von pseudomonas aeruginosa
CN1324049C (zh) 2003-08-04 2007-07-04 中国疾病预防控制中心病毒病预防控制所 人源抗sars冠状病毒基因工程抗体
US20050226878A1 (en) 2003-12-02 2005-10-13 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
TW200813091A (en) 2006-04-10 2008-03-16 Amgen Fremont Inc Targeted binding agents directed to uPAR and uses thereof
US20080131457A1 (en) 2006-06-12 2008-06-05 Nabi Biopharmaceuticals Use of alpha-toxin for treating and preventing staphylococcus infections
US20090075378A1 (en) 2007-02-20 2009-03-19 Anaptysbio, Inc. Somatic hypermutation systems
PL2188313T3 (pl) 2007-08-21 2018-04-30 Amgen, Inc. Białka wiążące ludzki antygen c-fms
JP5658564B2 (ja) 2007-08-31 2015-01-28 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物
JP2011526792A (ja) 2008-07-02 2011-10-20 エマージェント プロダクト デベロップメント シアトル, エルエルシー TNF−αアンタゴニスト多重標的結合性タンパク質
EP2208787A1 (en) 2009-01-19 2010-07-21 Université de Liège A recombinant alpha-hemolysin polypeptide of Staphylococcus aureus, having a deletion in the stem domain and heterologous sequences inserted
CN104119438A (zh) 2009-01-29 2014-10-29 米迪缪尼有限公司 延长体内半衰期的人抗il-6抗体及其在治疗肿瘤、自身免疫性疾病和炎症性疾病中的应用
MX2011012248A (es) 2009-05-18 2012-02-29 Univ Wuerzburg J Maximilians Anticuerpos o sus fragmentos dirigidos contra un epitope de staphylococcus aureus de isaa o isab.
EP4015523A1 (en) 2010-05-05 2022-06-22 New York University Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof
PT2673373T (pt) 2011-02-08 2018-12-05 Medimmune Llc Anticorpos que ligam especificamente a toxina alfa de staphylococcus aureus e métodos de utilização
NZ764564A (en) 2011-06-19 2022-10-28 Univ New York Methods of treating and preventing staphylococcus aureus infections and associated conditions
DK2833899T3 (da) 2012-03-19 2020-09-28 Tecnifar Ind Tecnica Farmaceutica S A Sammensætninger, der omfatter cocktails af antibakterielle fager, og anvendelser deraf til behandling af bakterieinfektioner
KR20210083389A (ko) 2012-11-06 2021-07-06 메디뮨 엘엘씨 에스.아우레우스 연관 질병의 치료 방법
BR112015010125A2 (pt) 2012-11-06 2017-08-22 Medimmune Llc Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente
RU2016119052A3 (en) 2013-10-17 2018-09-10 Arsanis Biosciences Gmbh Cross-reactive Staphylococcus aureus antibody sequences
CA2932819A1 (en) 2013-12-09 2015-06-18 New York University Compositions and methods for phagocyte delivery of anti-staphylococcal agents
MX2016007212A (es) 2013-12-19 2016-09-07 Arsanis Biosciences Gmbh Anticuerpos dirigidos contra la toxina lukgh (lukab) de staphylococcus aureus y secuencias de anticuerpos.
ES2869459T3 (es) 2014-05-16 2021-10-25 Medimmune Llc Moléculas con unión a receptor de fc de neonato alterada que tiene propiedades terapéuticas y de diagnóstico potenciadas
TWI719938B (zh) 2014-06-19 2021-03-01 美商麥迪紐有限責任公司 多重細菌感染之治療
CN107873034A (zh) 2015-04-17 2018-04-03 阿尔萨尼斯生物科学有限责任公司 抗金黄色葡萄球菌抗体组合制剂
WO2017075188A2 (en) * 2015-10-30 2017-05-04 Medimmune, Llc Methods of using anti-alpha toxin antibody
JP7525471B2 (ja) 2018-07-24 2024-07-30 メディミューン,エルエルシー S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体
BR112021006622A2 (pt) 2018-10-09 2021-07-20 Medimmune, Llc combinações de anticorpos anti-staphylococcus aureus
TWI895248B (zh) 2018-10-09 2025-09-01 美商麥迪紐有限責任公司 針對金黃色葡萄球菌白血球毒素的抗體

Similar Documents

Publication Publication Date Title
JP2021530244A5 (enExample)
JP2021534762A5 (enExample)
JP2022512132A5 (enExample)
JP2024105229A5 (enExample)
JP2023551027A5 (enExample)
HRP20190605T1 (hr) Protutijela anti-fxi i postupci njihove uporabe
JP7821159B2 (ja) Bcmaと結合する単一可変ドメイン及び抗原結合分子
JP7189211B2 (ja) 血清中のタンパク質の半減期を増加させるための組成物及び方法
JP2023540526A5 (enExample)
JP2020518248A5 (enExample)
JP2023509390A5 (enExample)
JP2017523984A5 (enExample)
JP2022512646A5 (enExample)
JP2023549537A5 (enExample)
JP2024516595A5 (enExample)
JP2024001073A5 (enExample)
JP2023511963A5 (enExample)
JP2023520969A5 (enExample)
JP7830445B2 (ja) インターロイキン1アルファに特異的な真のヒト抗体
US10640576B2 (en) Cell engaging binding molecules
FI4200018T3 (fi) Anti-par-2-vasta-aineet ja niiden käyttömenetelmät
CN106243223B (zh) 抗人pdl1抗体及其用途
JP2024516098A5 (enExample)
JP2025505650A5 (enExample)
JP2023550628A5 (enExample)