JP2017523984A5 - - Google Patents
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- Publication number
- JP2017523984A5 JP2017523984A5 JP2017506286A JP2017506286A JP2017523984A5 JP 2017523984 A5 JP2017523984 A5 JP 2017523984A5 JP 2017506286 A JP2017506286 A JP 2017506286A JP 2017506286 A JP2017506286 A JP 2017506286A JP 2017523984 A5 JP2017523984 A5 JP 2017523984A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- pharmaceutical composition
- ox40l
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462032959P | 2014-08-04 | 2014-08-04 | |
| US62/032,959 | 2014-08-04 | ||
| PCT/US2015/043408 WO2016022468A1 (en) | 2014-08-04 | 2015-08-03 | Antagonistic anti-ox40l antibodies and methods of their use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017523984A JP2017523984A (ja) | 2017-08-24 |
| JP2017523984A5 true JP2017523984A5 (enExample) | 2018-08-30 |
| JP6628787B2 JP6628787B2 (ja) | 2020-01-15 |
Family
ID=55264394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506286A Active JP6628787B2 (ja) | 2014-08-04 | 2015-08-03 | 拮抗性抗ｏｘ４０ｌ抗体およびそれらの使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10167339B2 (enExample) |
| EP (1) | EP3194445A4 (enExample) |
| JP (1) | JP6628787B2 (enExample) |
| CN (1) | CN107074951B (enExample) |
| AU (1) | AU2015301338C1 (enExample) |
| IL (1) | IL250428B (enExample) |
| WO (1) | WO2016022468A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| US9512229B2 (en) | 2015-03-03 | 2016-12-06 | Kymab Limited | Synergistic combinations of OX40L antibodies for the treatment of GVHD |
| US9434785B1 (en) | 2015-04-30 | 2016-09-06 | Kymab Limited | Anti-human OX40L antibodies and methods of treating graft versus host disease with the same |
| US20220372153A1 (en) * | 2015-03-03 | 2022-11-24 | Kymab Limited | Synergistic combinations of ox40l antibodies for the treatment of gvhd |
| TW201803905A (zh) | 2016-06-20 | 2018-02-01 | 克馬伯有限公司 | 用於免疫腫瘤學之多重專一性抗體 |
| EP3534947A1 (en) | 2016-11-03 | 2019-09-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| WO2018170764A1 (zh) * | 2017-03-22 | 2018-09-27 | 深圳市博奥康生物科技有限公司 | 一种用于 RNAi 的载体及其应用 |
| US20200283500A1 (en) * | 2017-10-18 | 2020-09-10 | Alpine Immune Sciences, Inc. | Variant icos ligand immunomodulatory proteins and related compositions and methods |
| CN108458964A (zh) * | 2017-10-31 | 2018-08-28 | 天津协和华美医学诊断技术有限公司 | 一种抗体组合物及其在淋巴浆细胞性淋巴瘤微小残留检测中的应用 |
| CA3129302A1 (en) * | 2019-03-12 | 2020-09-17 | Richard BROKX | Tsg-6 antibodies and uses therefor |
| JP7719775B2 (ja) * | 2019-12-06 | 2025-08-06 | アブリンクス エン．ヴェー． | ＴＮＦαおよびＯＸ４０Ｌを標的とする免疫グロブリン単一可変ドメインを含むポリペプチド |
| MX2022013176A (es) * | 2020-04-24 | 2022-11-30 | Millennium Pharm Inc | Anticuerpos anti cumulo de diferenciacion 19 (cd19) y sus usos. |
| CN117440967A (zh) * | 2020-12-09 | 2024-01-23 | 怡诺安有限公司 | 抗OX40L抗体、抗OX40L/抗TNFα双特异性抗体及其用途 |
| KR102705172B1 (ko) * | 2020-12-09 | 2024-09-11 | 에이치케이이노엔 주식회사 | 항 OX40L 항체, 항 OX40L 및 항 TNFα 이중 특이성 항체 및 이들의 용도 |
| JP2024530954A (ja) * | 2021-08-10 | 2024-08-27 | カイマブ・リミテッド | アトピー性皮膚炎の処置 |
| WO2025031290A1 (zh) * | 2023-08-04 | 2025-02-13 | 信达生物制药(苏州)有限公司 | 抗ox40l抗体以及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3914342B2 (ja) * | 1997-09-25 | 2007-05-16 | 武田薬品工業株式会社 | ｇｐ３４結合阻害物を有効成分として含有する医薬組成物 |
| US7291331B1 (en) * | 2002-09-11 | 2007-11-06 | La Jolla Institute For Allergy And Immunology | Methods of treating OX40 medicated recall immune responses |
| TWI309240B (en) * | 2004-09-17 | 2009-05-01 | Hoffmann La Roche | Anti-ox40l antibodies |
| TWI461436B (zh) * | 2005-11-25 | 2014-11-21 | Kyowa Hakko Kirin Co Ltd | 人類ｃｄ１３４（ｏｘ４０）之人類單株抗體及其製造及使用方法 |
| BRPI0621065A2 (pt) * | 2005-12-16 | 2011-11-29 | Genentech Inc | anticorpo anti-ox40l, anticorpos isolados, polinucleotìdeo, vetor, célula hospedeira, método para fabricar um anticorpo anti-ox40l, método para tratar ou previnir uma disfunção imune, composição e uso de um anticorpo anti-ox40l |
| EP2513145B1 (en) * | 2009-12-14 | 2018-01-24 | Ablynx N.V. | Single variable domain antibodies against ox40l, constructs and therapeutic use |
| US20120020960A1 (en) | 2010-07-26 | 2012-01-26 | Baylor Research Institute | Thymic Stromal Lymphopoietin (TSLP) and OX40 Ligand in Cancer |
-
2015
- 2015-08-03 CN CN201580052180.0A patent/CN107074951B/zh active Active
- 2015-08-03 US US15/501,526 patent/US10167339B2/en active Active
- 2015-08-03 EP EP15829426.4A patent/EP3194445A4/en active Pending
- 2015-08-03 JP JP2017506286A patent/JP6628787B2/ja active Active
- 2015-08-03 WO PCT/US2015/043408 patent/WO2016022468A1/en not_active Ceased
- 2015-08-03 AU AU2015301338A patent/AU2015301338C1/en active Active
-
2017
- 2017-02-02 IL IL250428A patent/IL250428B/en active IP Right Grant
-
2018
- 2018-12-05 US US16/210,188 patent/US10570208B2/en active Active
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