JP2021530229A5 - - Google Patents
Info
- Publication number
- JP2021530229A5 JP2021530229A5 JP2021502424A JP2021502424A JP2021530229A5 JP 2021530229 A5 JP2021530229 A5 JP 2021530229A5 JP 2021502424 A JP2021502424 A JP 2021502424A JP 2021502424 A JP2021502424 A JP 2021502424A JP 2021530229 A5 JP2021530229 A5 JP 2021530229A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- sequence described
- cdr
- Prior art date
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862698482P | 2018-07-16 | 2018-07-16 | |
| US62/698,482 | 2018-07-16 | ||
| US201962846989P | 2019-05-13 | 2019-05-13 | |
| US62/846,989 | 2019-05-13 | ||
| US201962866028P | 2019-06-25 | 2019-06-25 | |
| US62/866,028 | 2019-06-25 | ||
| PCT/US2019/041952 WO2020018503A2 (en) | 2018-07-16 | 2019-07-16 | Anti-il36r antibodies |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021530229A JP2021530229A (ja) | 2021-11-11 |
| JPWO2020018503A5 JPWO2020018503A5 (https=) | 2022-06-13 |
| JP2021530229A5 true JP2021530229A5 (https=) | 2022-06-13 |
| JP7386224B2 JP7386224B2 (ja) | 2023-11-24 |
Family
ID=67480435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502424A Active JP7386224B2 (ja) | 2018-07-16 | 2019-07-16 | 抗ｉｌ３６ｒ抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11267893B2 (https=) |
| EP (1) | EP3823989A2 (https=) |
| JP (1) | JP7386224B2 (https=) |
| KR (1) | KR102895164B1 (https=) |
| CN (1) | CN112513091B (https=) |
| AU (1) | AU2019306217B2 (https=) |
| BR (1) | BR112020027015A2 (https=) |
| CA (1) | CA3103531A1 (https=) |
| IL (1) | IL280013B1 (https=) |
| MX (2) | MX2021000566A (https=) |
| PH (1) | PH12020552178A1 (https=) |
| SG (1) | SG11202012360YA (https=) |
| WO (1) | WO2020018503A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016168542A1 (en) | 2015-04-15 | 2016-10-20 | Anaptysbio, Inc. | Antibodies directed against interleukin 36 receptor (il-36r) |
| CA3093692A1 (en) | 2018-03-14 | 2019-09-19 | Boehringer Ingelheim International Gmbh | Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis |
| MX2021000566A (es) | 2018-07-16 | 2021-06-23 | Regeneron Pharma | Anticuerpos anti-il36r. |
| EP4182022A1 (en) | 2020-07-17 | 2023-05-24 | Boehringer Ingelheim International GmbH | Anti-il-36r antibodies for the treatment of neutrophilic dermatoses |
| JP2023536851A (ja) | 2020-07-30 | 2023-08-30 | アナプティスバイオ インコーポレイティッド | 魚鱗癬のための抗インターロイキン３６受容体（ｉｌ－３６ｒ）療法 |
| WO2022026829A1 (en) | 2020-07-30 | 2022-02-03 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity |
| CN112094349B (zh) * | 2020-11-04 | 2021-02-09 | 上海华奥泰生物药业股份有限公司 | 靶向于白介素36r的抗体及其制备方法和应用 |
| EP4289863A4 (en) * | 2020-12-17 | 2025-04-09 | Shanghai Huaota Biopharmaceutical Co., Ltd. | BISPECIFIC ANTIBODY AGAINST IL-17A AND IL-36R AND USE THEREOF |
| WO2022150642A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa |
| WO2022150644A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for acne |
| WO2022166977A1 (zh) * | 2021-02-08 | 2022-08-11 | 上海普铭生物科技有限公司 | 抗人il-36r抗体及其应用 |
| CA3209006A1 (en) * | 2021-03-04 | 2022-09-09 | Boehringer Ingelheim International Gmbh | Methods for the treatment of gpp |
| WO2022192531A2 (en) | 2021-03-12 | 2022-09-15 | Boehringer Ingelheim International Gmbh | Biomarkers associated with anti-il-36r antibody treatment in generalized pustular psoriasis |
| CN117480183A (zh) * | 2021-06-18 | 2024-01-30 | 正大天晴药业集团股份有限公司 | 抗il-36r抗体及其用途 |
| EP4370550A1 (en) * | 2021-07-12 | 2024-05-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of il-36 inhibitors for the treatment of netherton syndrome |
| US20250120374A1 (en) * | 2021-10-25 | 2025-04-17 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric genes |
| TW202323293A (zh) * | 2021-10-29 | 2023-06-16 | 新加坡商創響私人有限公司 | 新型抗ｉｌ－３６ｒ抗體 |
| CN115724975A (zh) | 2022-10-20 | 2023-03-03 | 江苏荃信生物医药股份有限公司 | 抗人白介素36受体单克隆抗体及其应用 |
| CN116574189A (zh) * | 2023-01-30 | 2023-08-11 | 北京智仁美博生物科技有限公司 | 针对人il-36r和/或人il-1r3的多种抗体及其用途 |
| JP2026506716A (ja) | 2023-02-21 | 2026-02-25 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 | Ｉｌ－３６ｒ結合タンパク質及びその医薬的使用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4740461A (en) | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
| US5693489A (en) | 1984-03-30 | 1997-12-02 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
| US4952496A (en) | 1984-03-30 | 1990-08-28 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4959455A (en) | 1986-07-14 | 1990-09-25 | Genetics Institute, Inc. | Primate hematopoietic growth factors IL-3 and pharmaceutical compositions |
| US4912040A (en) | 1986-11-14 | 1990-03-27 | Genetics Institute, Inc. | Eucaryotic expression system |
| WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| US6239268B1 (en) | 1994-09-09 | 2001-05-29 | Neurocrine Biosciences, Inc. | Interleukin-1 type 3 receptors |
| JPH10508743A (ja) | 1994-09-09 | 1998-09-02 | ニューロクライン バイオサイエンシーズ， インコーポレイテッド | インターロイキン−１ タイプ３レセプター |
| US6326472B1 (en) | 1997-10-15 | 2001-12-04 | Schering Corporation | Human receptor proteins; related reagents and methods |
| WO1999019480A2 (en) | 1997-10-15 | 1999-04-22 | Schering Corporation | Human receptor proteins; related reagents and methods |
| US20060003323A1 (en) | 2000-03-01 | 2006-01-05 | John Alsobrook | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US6900016B1 (en) | 2000-09-08 | 2005-05-31 | Applera Corporation | Polymorphisms in known genes associated with inflammatory autoimmune disease, methods of detection and uses thereof |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US20030170630A1 (en) | 2000-12-21 | 2003-09-11 | Alsobrook John P. | Proteins and nucleic acids encoding same |
| WO2005100604A2 (en) | 2004-04-01 | 2005-10-27 | Sequenom, Inc. | Methods for identifying risk of osteoarthritis and treatments thereof |
| WO2005108415A2 (en) | 2004-04-30 | 2005-11-17 | Biogen Idec Ma Inc. | Membrane associated molecules |
| CA2625403A1 (en) | 2005-10-17 | 2007-04-26 | Institute For System Biology | Tissue-and serum-derived glycoproteins and methods of their use |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| KR102038310B1 (ko) | 2011-11-16 | 2019-11-01 | 베링거 인겔하임 인터내셔날 게엠베하 | 항 ｉｌ-36ｒ 항체 |
| US20150203591A1 (en) | 2012-08-02 | 2015-07-23 | Regeneron Pharmaceuticals, Inc. | Mutivalent antigen-binding proteins |
| WO2014144666A2 (en) * | 2013-03-15 | 2014-09-18 | The University Of Chicago | Methods and compositions related to t-cell activity |
| WO2016168542A1 (en) * | 2015-04-15 | 2016-10-20 | Anaptysbio, Inc. | Antibodies directed against interleukin 36 receptor (il-36r) |
| JP2020512344A (ja) | 2017-03-27 | 2020-04-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗ｉｌ−３６ｒ抗体併用治療 |
| AU2019234478A1 (en) | 2018-03-14 | 2020-08-20 | Boehringer Ingelheim International Gmbh | Use of anti-IL36R antibodies for treatment of inflammatory bowel disease |
| CA3093692A1 (en) | 2018-03-14 | 2019-09-19 | Boehringer Ingelheim International Gmbh | Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis |
| MX2021000566A (es) | 2018-07-16 | 2021-06-23 | Regeneron Pharma | Anticuerpos anti-il36r. |
| IL278267B2 (en) | 2018-07-16 | 2025-02-01 | Regeneron Pharma | Non-human animal models of DITRA disease and their uses |
-
2019
- 2019-07-16 MX MX2021000566A patent/MX2021000566A/es unknown
- 2019-07-16 SG SG11202012360YA patent/SG11202012360YA/en unknown
- 2019-07-16 CN CN201980050334.0A patent/CN112513091B/zh active Active
- 2019-07-16 US US16/512,886 patent/US11267893B2/en active Active
- 2019-07-16 JP JP2021502424A patent/JP7386224B2/ja active Active
- 2019-07-16 BR BR112020027015-6A patent/BR112020027015A2/pt unknown
- 2019-07-16 CA CA3103531A patent/CA3103531A1/en active Pending
- 2019-07-16 KR KR1020217002970A patent/KR102895164B1/ko active Active
- 2019-07-16 AU AU2019306217A patent/AU2019306217B2/en active Active
- 2019-07-16 EP EP19746372.2A patent/EP3823989A2/en active Pending
- 2019-07-16 WO PCT/US2019/041952 patent/WO2020018503A2/en not_active Ceased
-
2020
- 2020-12-15 PH PH12020552178A patent/PH12020552178A1/en unknown
-
2021
- 2021-01-07 IL IL280013A patent/IL280013B1/en unknown
- 2021-01-14 MX MX2025007735A patent/MX2025007735A/es unknown
-
2022
- 2022-02-01 US US17/590,319 patent/US12060428B2/en active Active
-
2024
- 2024-07-01 US US18/760,617 patent/US20250011442A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021530229A5 (https=) | ||
| JP7386224B2 (ja) | 抗ｉｌ３６ｒ抗体 | |
| TWI432210B (zh) | 人類ｉｌ－２３抗原結合蛋白 | |
| JP6289520B2 (ja) | 中和抗ｃｃｌ２０抗体 | |
| JP7517999B2 (ja) | 抗ＩＬ－２３ｐ１９抗体およびその使用 | |
| US20200010571A1 (en) | Bispecific Anti-TNF-Alpha/IL-17A Antibodies and Anti-TNF-Alpha Antibodies and Methods of Their Use | |
| JP6825033B2 (ja) | Ｂａｆｆ及びｂ７ｒｐ１に特異的なタンパク質及びその使用 | |
| JPWO2020018503A5 (https=) | ||
| JP5818804B2 (ja) | ヒトｉｌ−２２ｒａに対するヒト化抗体 | |
| JP6410712B2 (ja) | Ｉｌ−６結合分子 | |
| KR20110040886A (ko) | 프로스타글란딘 ｅ2 결합 단백질 및 이의 용도 | |
| KR20110110349A (ko) | Ｉｌ-1 결합 단백질 | |
| JP2017533705A (ja) | 抗ｔｎｆ−／抗ｉｌ−２３二重特異性抗体 | |
| TW201917135A (zh) | 抗ＴＮＦ／抗ＩＬ-２３ ＩｇＧ雙特異性抗體 | |
| CN108473568A (zh) | 对TNF-α、IL-17A和IL-17F具有特异性的多特异性抗体分子 | |
| WO2019148405A1 (zh) | IL-4Rα抗体及其用途 | |
| CN113166239B (zh) | 抗il-17a抗体及其应用 | |
| WO2016070769A1 (zh) | 同时阻断b7/cd28和il6/il6r/gp130信号通路的重组融合蛋白 | |
| TW202144425A (zh) | 特異性抗原結合分子，其製備方法及醫藥用途 | |
| EP4357361A1 (en) | Anti-il-36r antibody and use thereof | |
| US12134644B2 (en) | Anti-IL-17A antibodies and use thereof | |
| HK40123789A (zh) | 优化的抗tl1a抗体 | |
| HK40042163B (zh) | 优化的抗tl1a抗体 | |
| EA049652B1 (ru) | Антитела к il36r |