|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
|
GB8905592D0
(en)
|
1989-03-10 |
1989-04-19 |
Gkn Technology Ltd |
Automatic length adjuster
|
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
|
US5270163A
(en)
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
|
DK0553244T4
(da)
|
1990-10-05 |
2005-08-01 |
Celldex Therapeutics Inc |
Målrettet immunostimulering med bispecifikke reagenser
|
|
WO1992008802A1
(en)
|
1990-10-29 |
1992-05-29 |
Cetus Oncology Corporation |
Bispecific antibodies, method of production, and uses thereof
|
|
CA2108451A1
(en)
|
1991-04-26 |
1992-10-27 |
Beverley J. Randle |
Novel antibodies, and methods for their use
|
|
PT627940E
(pt)
|
1992-03-05 |
2003-07-31 |
Univ Texas |
Utilizacao de imunoconjugados para o diagnostico e/ou terapia de tumores vascularizados
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
WO2003060064A2
(en)
|
2001-07-12 |
2003-07-24 |
Incyte Genomics, Inc. |
Intracellular signaling molecules
|
|
SG114505A1
(en)
|
2001-10-17 |
2005-09-28 |
First Cube Pte Ltd |
System and method for facilitating delivery and return service
|
|
WO2003049527A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1620092A4
(en)
|
2003-05-07 |
2008-04-16 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
|
EP2478912B1
(en)
|
2003-11-06 |
2016-08-31 |
Seattle Genetics, Inc. |
Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy
|
|
KR20060127413A
(ko)
|
2003-11-25 |
2006-12-12 |
카이론 코포레이션 |
항암제로서의 퀴나졸리논 화합물
|
|
DE10355904A1
(de)
*
|
2003-11-29 |
2005-06-30 |
Merck Patent Gmbh |
Feste Formen von anti-EGFR-Antikörpern
|
|
US7662581B1
(en)
|
2003-12-18 |
2010-02-16 |
Novartis Vaccines And Diagnostics, Inc. |
Eg5 co-crystals
|
|
BRPI0510929A
(pt)
|
2004-06-18 |
2007-07-17 |
Chiron Corp |
derivados de n-(1-(1-benzil-4-fenil-1h-imidazol-2-il)-2,2-dimetilpropil) benzamida e compostos relacionados como inibidores de proteìna de eixo de kinesin (ksp) para o tratamento de cáncer
|
|
US7449486B2
(en)
|
2004-10-19 |
2008-11-11 |
Array Biopharma Inc. |
Mitotic kinesin inhibitors and methods of use thereof
|
|
WO2006060737A2
(en)
|
2004-12-03 |
2006-06-08 |
Takeda San Diego, Inc. |
Mitotic kinesin inhibitors
|
|
TW200800951A
(en)
|
2005-08-09 |
2008-01-01 |
Novartis Ag |
Substituted imidazole compounds as KSP inhibitors
|
|
DOP2006000277A
(es)
|
2005-12-12 |
2007-08-31 |
Bayer Pharmaceuticals Corp |
Anticuerpos anti mn y métodos para su utilización
|
|
WO2008086122A2
(en)
|
2007-01-05 |
2008-07-17 |
Novartis Ag |
Imidazole derivatives as kinesin spindle protein inhibitors (eg-5)
|
|
MX338397B
(es)
*
|
2007-08-29 |
2016-04-15 |
Sanofi Aventis |
Anticuerpos anti - cxcr5 humanizados, derivados de los mismos y su uso.
|
|
WO2012171020A1
(en)
|
2011-06-10 |
2012-12-13 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
|
EP2968591A1
(en)
|
2013-03-15 |
2016-01-20 |
Novartis AG |
Cell proliferation inhibitors and conjugates thereof
|
|
SG11201508502RA
(en)
|
2013-05-02 |
2015-11-27 |
Ares Trading Sa |
Monoclonal antibody directed against cxcr5
|
|
RU2698697C2
(ru)
|
2013-12-23 |
2019-08-29 |
Байер Фарма Акциенгезельшафт |
Конъюгаты связующего (ADC) с ингибиторами KSP
|
|
CA2970565A1
(en)
|
2014-12-15 |
2016-06-23 |
Bayer Pharma Aktiengesellschaft |
Antibody-drug conjugates (adcs) of ksp inhibitors with aglycosylated anti-tweakr antibodies
|
|
JP6971858B2
(ja)
*
|
2015-06-22 |
2021-11-24 |
バイエル ファーマ アクチエンゲゼルシャフト |
酵素開裂性基を有する抗体薬物複合体（ａｄｃ）および抗体プロドラッグ複合体（ａｐｄｃ）
|
|
JP7251981B2
(ja)
*
|
2016-03-24 |
2023-04-04 |
バイエル ファーマ アクチエンゲゼルシャフト |
酵素開裂基を有する細胞毒性活性剤のプロドラッグ
|
|
CN110312534B
(zh)
*
|
2016-12-21 |
2023-04-04 |
拜耳制药股份公司 |
具有酶促可裂解基团的抗体-药物-缀合物(adc)
|