JP2021527087A5 - - Google Patents

Info

Publication number
JP2021527087A5
JP2021527087A5 JP2020568984A JP2020568984A JP2021527087A5 JP 2021527087 A5 JP2021527087 A5 JP 2021527087A5 JP 2020568984 A JP2020568984 A JP 2020568984A JP 2020568984 A JP2020568984 A JP 2020568984A JP 2021527087 A5 JP2021527087 A5 JP 2021527087A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
microrna
promoter
mir145
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2020568984A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021527087A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/037174 external-priority patent/WO2019241624A1/en
Publication of JP2021527087A publication Critical patent/JP2021527087A/ja
Publication of JP2021527087A5 publication Critical patent/JP2021527087A5/ja
Withdrawn legal-status Critical Current

Links

JP2020568984A 2018-06-14 2019-06-14 アンジェルマン症候群の処置におけるMIR−92aまたはMIR−145の使用 Withdrawn JP2021527087A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862684774P 2018-06-14 2018-06-14
US62/684,774 2018-06-14
PCT/US2019/037174 WO2019241624A1 (en) 2018-06-14 2019-06-14 Use of mir-92a or mir-145 in the treatment of angelman syndrome

Publications (2)

Publication Number Publication Date
JP2021527087A JP2021527087A (ja) 2021-10-11
JP2021527087A5 true JP2021527087A5 (https=) 2022-06-10

Family

ID=68839583

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020568984A Withdrawn JP2021527087A (ja) 2018-06-14 2019-06-14 アンジェルマン症候群の処置におけるMIR−92aまたはMIR−145の使用

Country Status (10)

Country Link
US (2) US10704048B2 (https=)
EP (1) EP3793567A4 (https=)
JP (1) JP2021527087A (https=)
KR (1) KR20210040358A (https=)
CN (1) CN112739353A (https=)
AU (1) AU2019285298A1 (https=)
CA (1) CA3103267A1 (https=)
IL (1) IL279391A (https=)
MX (1) MX2020013667A (https=)
WO (1) WO2019241624A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018320849A1 (en) * 2017-08-25 2020-03-05 Ovid Therapeutics Inc. Recombinant adeno-associated vectors
KR20210040358A (ko) 2018-06-14 2021-04-13 오비드 테라퓨틱스 인크. 안젤만 증후군의 치료에서 mir-92a 또는 mir-145의 사용
WO2020227604A1 (en) * 2019-05-08 2020-11-12 Nova Southeastern University Regulation of nucleotide excision repair (ner) by microrna for treatment of breast cancer
IL303239A (en) * 2020-12-01 2023-07-01 Univ Pennsylvania Compositions and their uses for the treatment of Engelmann syndrome

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5752515A (en) 1996-08-21 1998-05-19 Brigham & Women's Hospital Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier
WO2006128245A1 (en) 2005-06-03 2006-12-07 Southern Adelaide Health Service-Flinders Medical Centre Targeting cells with altered microrna expression
EP1937151A4 (en) 2005-09-19 2011-07-06 Univ Columbia Systems and methods for opening of the blood-brain barrier of a subject using ultrasound
CN102676516B (zh) * 2011-03-17 2014-06-04 中国医学科学院肿瘤研究所 microRNA 145的新用途
US20150267193A1 (en) * 2011-10-14 2015-09-24 Ramanuj Dasgupta MicroRNAs and Methods of Using Same
EA201492116A1 (ru) * 2012-05-16 2015-05-29 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии mecp2
WO2014004572A2 (en) 2012-06-25 2014-01-03 Isis Pharmaceuticals, Inc. Modulation of ube3a-ats expression
EP3291843B1 (en) 2015-05-07 2023-03-22 University of South Florida Modified ube3a gene for a gene therapy approach for angelman syndrome
US20190298843A1 (en) * 2015-05-11 2019-10-03 Purdue Research Foundation Ligand ionophore conjugates
EP4541420A3 (en) * 2015-07-17 2025-06-25 Ovid Therapeutics Inc. Methods of treating developmental disorders with gaboxadol
KR20210040358A (ko) 2018-06-14 2021-04-13 오비드 테라퓨틱스 인크. 안젤만 증후군의 치료에서 mir-92a 또는 mir-145의 사용

Similar Documents

Publication Publication Date Title
JP2021527087A5 (https=)
JP2022508182A5 (https=)
US10392632B2 (en) AAV8 vector with enhanced functional activity and methods of use thereof
JP2021512649A5 (https=)
US10413598B2 (en) Factor IX gene therapy
JP2020522269A5 (https=)
RU2020109343A (ru) Полинуклеотиды aadc для лечения болезни паркинсона
JP2022529631A5 (https=)
JP2021500049A (ja) 神経変性疾患の遺伝子治療
JP2021511803A5 (https=)
IL299325B2 (en) Acid-alpha glucosidase variants and uses thereof
JP2022501060A5 (https=)
JP2021512072A5 (https=)
JP2020537542A (ja) ライソゾーム病の遺伝子治療
JP2023534037A5 (https=)
KR20240090694A (ko) 변종 aav 및 조성물, 세포, 기관 및 조직으로의 유전자 전이를 위한 방법 및 용도
KR20210096168A (ko) 신경퇴행성 질환을 위한 유전자 요법
JP2023500793A (ja) アルツハイマー病に対する遺伝子治療方法
JP2018533976A5 (https=)
JP2023537358A5 (https=)
JP2021531044A5 (https=)
JP2021533801A5 (https=)
CN114231532B (zh) 在哺乳动物肌肉中特异性启动基因的启动子序列及其应用
JP2018526994A5 (https=)
JP2020510433A5 (https=)