CN112739353A - Mir-92a或mir-145在治疗安格曼综合征中的用途 - Google Patents
Mir-92a或mir-145在治疗安格曼综合征中的用途 Download PDFInfo
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- CN112739353A CN112739353A CN201980040006.2A CN201980040006A CN112739353A CN 112739353 A CN112739353 A CN 112739353A CN 201980040006 A CN201980040006 A CN 201980040006A CN 112739353 A CN112739353 A CN 112739353A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/00—Structure or type of the nucleic acid
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Applications Claiming Priority (3)
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| US201862684774P | 2018-06-14 | 2018-06-14 | |
| US62/684,774 | 2018-06-14 | ||
| PCT/US2019/037174 WO2019241624A1 (en) | 2018-06-14 | 2019-06-14 | Use of mir-92a or mir-145 in the treatment of angelman syndrome |
Publications (1)
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| CN112739353A true CN112739353A (zh) | 2021-04-30 |
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| CN201980040006.2A Pending CN112739353A (zh) | 2018-06-14 | 2019-06-14 | Mir-92a或mir-145在治疗安格曼综合征中的用途 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111163811A (zh) * | 2017-08-25 | 2020-05-15 | 奥维德医疗公司 | 重组腺相关载体 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MX2020013667A (es) | 2018-06-14 | 2021-03-02 | Ovid Therapeutics Inc | Uso de mir-92a o mir-145 en el tratamiento del sindrome de angelman. |
| WO2020227604A1 (en) * | 2019-05-08 | 2020-11-12 | Nova Southeastern University | Regulation of nucleotide excision repair (ner) by microrna for treatment of breast cancer |
| KR20230128001A (ko) * | 2020-12-01 | 2023-09-01 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 엔젤만 증후군의 치료를 위한 조성물 및 이의 용도 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102676516A (zh) * | 2011-03-17 | 2012-09-19 | 中国医学科学院肿瘤研究所 | microRNA 145的新用途 |
| US20150267193A1 (en) * | 2011-10-14 | 2015-09-24 | Ramanuj Dasgupta | MicroRNAs and Methods of Using Same |
| CN107530451A (zh) * | 2015-05-07 | 2018-01-02 | 南佛罗里达大学 | 用于天使人综合征的基因治疗方法的修饰的ube3a基因 |
| CN108024997A (zh) * | 2015-07-17 | 2018-05-11 | 奥维德医疗公司 | 用加波沙朵治疗发育障碍的方法 |
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| US5752515A (en) | 1996-08-21 | 1998-05-19 | Brigham & Women's Hospital | Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier |
| WO2006128245A1 (en) | 2005-06-03 | 2006-12-07 | Southern Adelaide Health Service-Flinders Medical Centre | Targeting cells with altered microrna expression |
| EP1937151A4 (en) | 2005-09-19 | 2011-07-06 | Univ Columbia | Systems and methods for opening of the blood-brain barrier of a subject using ultrasound |
| AU2013262709A1 (en) * | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating MECP2 expression |
| ES2809199T3 (es) | 2012-06-25 | 2021-03-03 | Ionis Pharmaceuticals Inc | Modulación de la expresión de UBE3A-ATS |
| US20190298843A1 (en) * | 2015-05-11 | 2019-10-03 | Purdue Research Foundation | Ligand ionophore conjugates |
| MX2020013667A (es) | 2018-06-14 | 2021-03-02 | Ovid Therapeutics Inc | Uso de mir-92a o mir-145 en el tratamiento del sindrome de angelman. |
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2019
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102676516A (zh) * | 2011-03-17 | 2012-09-19 | 中国医学科学院肿瘤研究所 | microRNA 145的新用途 |
| US20150267193A1 (en) * | 2011-10-14 | 2015-09-24 | Ramanuj Dasgupta | MicroRNAs and Methods of Using Same |
| CN107530451A (zh) * | 2015-05-07 | 2018-01-02 | 南佛罗里达大学 | 用于天使人综合征的基因治疗方法的修饰的ube3a基因 |
| CN108024997A (zh) * | 2015-07-17 | 2018-05-11 | 奥维德医疗公司 | 用加波沙朵治疗发育障碍的方法 |
Non-Patent Citations (1)
| Title |
|---|
| LINYAN MENG等: "Towards a therapy for Angelman syndrome by targeting a long non-coding RNA", NATURE, vol. 518, no. 7539, pages 409 - 412, XP055556384, DOI: 10.1038/nature13975 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111163811A (zh) * | 2017-08-25 | 2020-05-15 | 奥维德医疗公司 | 重组腺相关载体 |
Also Published As
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| US11130952B2 (en) | 2021-09-28 |
| WO2019241624A1 (en) | 2019-12-19 |
| US20200332294A1 (en) | 2020-10-22 |
| US20190382761A1 (en) | 2019-12-19 |
| MX2020013667A (es) | 2021-03-02 |
| EP3793567A1 (en) | 2021-03-24 |
| IL279391A (en) | 2021-01-31 |
| CA3103267A1 (en) | 2019-12-19 |
| KR20210040358A (ko) | 2021-04-13 |
| US10704048B2 (en) | 2020-07-07 |
| JP2021527087A (ja) | 2021-10-11 |
| AU2019285298A1 (en) | 2021-01-07 |
| EP3793567A4 (en) | 2021-08-11 |
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