JP2021526123A5 - - Google Patents

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Publication number
JP2021526123A5
JP2021526123A5 JP2020540731A JP2020540731A JP2021526123A5 JP 2021526123 A5 JP2021526123 A5 JP 2021526123A5 JP 2020540731 A JP2020540731 A JP 2020540731A JP 2020540731 A JP2020540731 A JP 2020540731A JP 2021526123 A5 JP2021526123 A5 JP 2021526123A5
Authority
JP
Japan
Prior art keywords
alkyl
heterocycloalkyl
cycloalkyl
heteroaryl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020540731A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021526123A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2019/089025 external-priority patent/WO2019228403A1/en
Publication of JP2021526123A publication Critical patent/JP2021526123A/ja
Publication of JP2021526123A5 publication Critical patent/JP2021526123A5/ja
Pending legal-status Critical Current

Links

JP2020540731A 2018-05-29 2019-05-29 オートタキシン阻害剤とその使用 Pending JP2021526123A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862677459P 2018-05-29 2018-05-29
US62/677,459 2018-05-29
US201862731003P 2018-09-13 2018-09-13
US62/731,003 2018-09-13
PCT/CN2019/089025 WO2019228403A1 (en) 2018-05-29 2019-05-29 Autotaxin inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2021526123A JP2021526123A (ja) 2021-09-30
JP2021526123A5 true JP2021526123A5 (enExample) 2022-05-27

Family

ID=68697812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020540731A Pending JP2021526123A (ja) 2018-05-29 2019-05-29 オートタキシン阻害剤とその使用

Country Status (6)

Country Link
US (2) US10711000B2 (enExample)
EP (1) EP3728257A4 (enExample)
JP (1) JP2021526123A (enExample)
CN (1) CN111801328B (enExample)
CA (1) CA3089527A1 (enExample)
WO (1) WO2019228403A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111620865B (zh) * 2018-02-14 2021-06-11 苏州信诺维医药科技股份有限公司 一种杂环化合物、其应用及含其的药物组合物
WO2019228403A1 (en) 2018-05-29 2019-12-05 Fronthera U.S. Pharmaceuticals Llc Autotaxin inhibitors and uses thereof
CN111393459B (zh) * 2020-04-16 2022-07-22 南京安纳康生物科技有限公司 Shp2抑制剂及其用途
US20230295159A1 (en) * 2020-07-09 2023-09-21 Suzhou Ark Biopharmaceutical Co., Ltd. Atx inhibitor, and preparation method therefor and use thereof
CN113912600A (zh) * 2020-07-09 2022-01-11 苏州爱科百发生物医药技术有限公司 一种atx抑制剂及其制备方法和应用
JP2023536159A (ja) * 2020-07-31 2023-08-23 ジェネンテック， インコーポレイテッド 炎症性呼吸器疾患の増悪を治療するための方法
CN114315825A (zh) * 2020-09-30 2022-04-12 江西济民可信集团有限公司 吡啶并咪唑衍生物及其制备方法和应用
WO2022074459A2 (en) * 2020-10-06 2022-04-14 Ildong Pharmaceutical Co., Ltd. Autotaxin inhibitor compounds
EP4242208A4 (en) * 2020-11-04 2025-01-15 Xizang Haisco Pharmaceutical Co., Ltd. DEUTERATED DERIVATIVE USED AS ATX INHIBITOR, AND ITS APPLICATION
CN112675308B (zh) * 2020-12-09 2023-05-05 中国人民解放军军事科学院军事医学研究院 抑制enpp2基因和/或蛋白表达的物质在制备治疗多发性骨髓瘤的药物中的应用
JP2024502337A (ja) 2021-01-05 2024-01-18 ザイダス ライフサイエンシズ リミティド オートタキシンの新規阻害剤
TW202309022A (zh) 2021-04-13 2023-03-01 美商努法倫特公司 用於治療具egfr突變之癌症之胺基取代雜環
TW202342138A (zh) * 2022-03-31 2023-11-01 大陸商蘇州愛科百發生物醫藥技術有限公司 Ａｔｘ抑制劑或其鹽的結晶形式及其制備方法與應用
EP4514348A4 (en) * 2022-04-29 2025-12-31 Noetix Pharma Llc PREVENTION AND TREATMENT OF POSTOPERATIVE COGNITIVE DYSFUNCTIONS (POCD)
EP4543870A1 (en) * 2022-06-24 2025-04-30 F. Hoffmann-La Roche AG New heterocyclic-carbonyl-cyclic compounds as magl inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2675818C2 (ru) * 2013-03-14 2018-12-25 Галапаго Нв Новые соединения и фармацевтические композиции, их содержащие, для лечения воспалительных расстройств
EP3010922B1 (en) * 2013-06-19 2017-03-15 Galapagos NV Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
TW201908293A (zh) * 2017-07-12 2019-03-01 美商必治妥美雅史谷比公司 作為rock抑制劑之5員及雙環雜環醯胺
CN111620865B (zh) * 2018-02-14 2021-06-11 苏州信诺维医药科技股份有限公司 一种杂环化合物、其应用及含其的药物组合物
CA3108809C (en) 2018-05-24 2023-08-29 Guangzhou Henovcom Bioscience Co., Ltd. Heteroaromatic compounds, pharmaceutical compositions and uses thereof
WO2019228403A1 (en) 2018-05-29 2019-12-05 Fronthera U.S. Pharmaceuticals Llc Autotaxin inhibitors and uses thereof

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