JP2021525771A5 - - Google Patents
Info
- Publication number
- JP2021525771A5 JP2021525771A5 JP2020567199A JP2020567199A JP2021525771A5 JP 2021525771 A5 JP2021525771 A5 JP 2021525771A5 JP 2020567199 A JP2020567199 A JP 2020567199A JP 2020567199 A JP2020567199 A JP 2020567199A JP 2021525771 A5 JP2021525771 A5 JP 2021525771A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- compound
- pharmaceutically acceptable
- group
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862680324P | 2018-06-04 | 2018-06-04 | |
| US62/680,324 | 2018-06-04 | ||
| PCT/US2019/035247 WO2019236496A1 (en) | 2018-06-04 | 2019-06-03 | Pyrimidine compounds containing acidic groups useful to treat diseases connected to the modulation of tlr7 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021525771A JP2021525771A (ja) | 2021-09-27 |
| JP2021525771A5 true JP2021525771A5 (https=) | 2022-06-06 |
| JPWO2019236496A5 JPWO2019236496A5 (https=) | 2022-06-06 |
| JP7351859B2 JP7351859B2 (ja) | 2023-09-27 |
Family
ID=66913097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567199A Active JP7351859B2 (ja) | 2018-06-04 | 2019-06-03 | Ｔｌｒ７の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10857153B2 (https=) |
| EP (1) | EP3802519A1 (https=) |
| JP (1) | JP7351859B2 (https=) |
| CN (1) | CN112513031A (https=) |
| AR (1) | AR114910A1 (https=) |
| TW (1) | TW202003475A (https=) |
| WO (1) | WO2019236496A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10786502B2 (en) | 2016-12-05 | 2020-09-29 | Apros Therapeutics, Inc. | Substituted pyrimidines containing acidic groups as TLR7 modulators |
| JP7351859B2 (ja) | 2018-06-04 | 2023-09-27 | アプロス セラピューティクス， インコーポレイテッド | Ｔｌｒ７の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73534A (en) | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| US6291455B1 (en) | 1996-03-05 | 2001-09-18 | Zeneca Limited | 4-anilinoquinazoline derivatives |
| ATE283855T1 (de) | 1996-07-03 | 2004-12-15 | Sumitomo Pharma | Neue purinderivate |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| DE69837529T2 (de) | 1997-02-12 | 2007-07-26 | Electrophoretics Ltd., Cobham | Proteinmarker für lungenkrebs und deren verwendung |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| NZ504800A (en) | 1997-11-28 | 2001-10-26 | Sumitomo Pharma | 6-Amino-9-benzyl-8-hydroxy-purine derivatives and interferon inducers, antiviral agents, anticancer agents and therapeutic agents for immunologic diseases thereof |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| SK288365B6 (sk) | 1999-02-10 | 2016-07-01 | Astrazeneca Ab | Medziprodukty pre chinazolínové deriváty ako inhibítory angiogenézy |
| CZ301689B6 (cs) | 1999-11-05 | 2010-05-26 | Astrazeneca Ab | Derivát chinazolinu a farmaceutický prostredek, který ho obsahuje |
| SI1255752T1 (sl) | 2000-02-15 | 2007-12-31 | Pharmacia & Upjohn Co Llc | S pirolom substituirani zaviralci 2-indolinon protein kinaza |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| CN1255392C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管生成抑制剂的秋水仙醇衍生物 |
| IL153484A0 (en) | 2000-07-07 | 2003-07-06 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors |
| EP2041135A4 (en) | 2006-07-05 | 2010-12-01 | Astrazeneca Ab | As TLR7 MODULATORS, 8-OXOADENINE DERIVATIVES WORK |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| CN102482233A (zh) | 2009-05-21 | 2012-05-30 | 阿斯利康(瑞典)有限公司 | 新颖的嘧啶衍生物和它们在治疗癌症和其它疾病中的用途 |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| ES2458355T3 (es) * | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
| WO2012066336A1 (en) | 2010-11-19 | 2012-05-24 | Astrazeneca Ab | Benzylamine compounds as toll -like receptor 7 agonists |
| TWI619704B (zh) | 2012-05-18 | 2018-04-01 | 大日本住友製藥股份有限公司 | 羧酸化合物 |
| WO2014128189A1 (en) | 2013-02-21 | 2014-08-28 | Janssen R&D Ireland | 2-aminopyrimidine derivatives for the treatment of viral infections |
| KR102495436B1 (ko) | 2016-12-05 | 2023-02-02 | 에이프로스 테라퓨틱스, 인크. | 산성 기를 함유하는 피리미딘 화합물 |
| US10786502B2 (en) | 2016-12-05 | 2020-09-29 | Apros Therapeutics, Inc. | Substituted pyrimidines containing acidic groups as TLR7 modulators |
| JP7351859B2 (ja) | 2018-06-04 | 2023-09-27 | アプロス セラピューティクス， インコーポレイテッド | Ｔｌｒ７の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物 |
-
2019
- 2019-06-03 JP JP2020567199A patent/JP7351859B2/ja active Active
- 2019-06-03 EP EP19731568.2A patent/EP3802519A1/en not_active Withdrawn
- 2019-06-03 AR ARP190101499A patent/AR114910A1/es unknown
- 2019-06-03 TW TW108119118A patent/TW202003475A/zh unknown
- 2019-06-03 US US16/429,104 patent/US10857153B2/en not_active Expired - Fee Related
- 2019-06-03 WO PCT/US2019/035247 patent/WO2019236496A1/en not_active Ceased
- 2019-06-03 CN CN201980050020.0A patent/CN112513031A/zh active Pending
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