TW202003475A - 含酸性基團之嘧啶化合物 - Google Patents
含酸性基團之嘧啶化合物 Download PDFInfo
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- TW202003475A TW202003475A TW108119118A TW108119118A TW202003475A TW 202003475 A TW202003475 A TW 202003475A TW 108119118 A TW108119118 A TW 108119118A TW 108119118 A TW108119118 A TW 108119118A TW 202003475 A TW202003475 A TW 202003475A
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
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| ATE283855T1 (de) | 1996-07-03 | 2004-12-15 | Sumitomo Pharma | Neue purinderivate |
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| SK288365B6 (sk) | 1999-02-10 | 2016-07-01 | Astrazeneca Ab | Medziprodukty pre chinazolínové deriváty ako inhibítory angiogenézy |
| CZ301689B6 (cs) | 1999-11-05 | 2010-05-26 | Astrazeneca Ab | Derivát chinazolinu a farmaceutický prostredek, který ho obsahuje |
| SI1255752T1 (sl) | 2000-02-15 | 2007-12-31 | Pharmacia & Upjohn Co Llc | S pirolom substituirani zaviralci 2-indolinon protein kinaza |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| CN1255392C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管生成抑制剂的秋水仙醇衍生物 |
| IL153484A0 (en) | 2000-07-07 | 2003-07-06 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors |
| EP2041135A4 (en) | 2006-07-05 | 2010-12-01 | Astrazeneca Ab | As TLR7 MODULATORS, 8-OXOADENINE DERIVATIVES WORK |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| CN102482233A (zh) | 2009-05-21 | 2012-05-30 | 阿斯利康(瑞典)有限公司 | 新颖的嘧啶衍生物和它们在治疗癌症和其它疾病中的用途 |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| ES2458355T3 (es) * | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
| WO2012066336A1 (en) | 2010-11-19 | 2012-05-24 | Astrazeneca Ab | Benzylamine compounds as toll -like receptor 7 agonists |
| TWI619704B (zh) | 2012-05-18 | 2018-04-01 | 大日本住友製藥股份有限公司 | 羧酸化合物 |
| WO2014128189A1 (en) | 2013-02-21 | 2014-08-28 | Janssen R&D Ireland | 2-aminopyrimidine derivatives for the treatment of viral infections |
| KR102495436B1 (ko) | 2016-12-05 | 2023-02-02 | 에이프로스 테라퓨틱스, 인크. | 산성 기를 함유하는 피리미딘 화합물 |
| US10786502B2 (en) | 2016-12-05 | 2020-09-29 | Apros Therapeutics, Inc. | Substituted pyrimidines containing acidic groups as TLR7 modulators |
| JP7351859B2 (ja) | 2018-06-04 | 2023-09-27 | アプロス セラピューティクス, インコーポレイテッド | Tlr7の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物 |
-
2019
- 2019-06-03 JP JP2020567199A patent/JP7351859B2/ja active Active
- 2019-06-03 EP EP19731568.2A patent/EP3802519A1/en not_active Withdrawn
- 2019-06-03 AR ARP190101499A patent/AR114910A1/es unknown
- 2019-06-03 TW TW108119118A patent/TW202003475A/zh unknown
- 2019-06-03 US US16/429,104 patent/US10857153B2/en not_active Expired - Fee Related
- 2019-06-03 WO PCT/US2019/035247 patent/WO2019236496A1/en not_active Ceased
- 2019-06-03 CN CN201980050020.0A patent/CN112513031A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR114910A1 (es) | 2020-10-28 |
| US20190365756A1 (en) | 2019-12-05 |
| JP2021525771A (ja) | 2021-09-27 |
| WO2019236496A1 (en) | 2019-12-12 |
| US10857153B2 (en) | 2020-12-08 |
| JP7351859B2 (ja) | 2023-09-27 |
| CN112513031A (zh) | 2021-03-16 |
| EP3802519A1 (en) | 2021-04-14 |
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