JP2023071933A5 - - Google Patents
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- JP2023071933A5 JP2023071933A5 JP2023035224A JP2023035224A JP2023071933A5 JP 2023071933 A5 JP2023071933 A5 JP 2023071933A5 JP 2023035224 A JP2023035224 A JP 2023035224A JP 2023035224 A JP2023035224 A JP 2023035224A JP 2023071933 A5 JP2023071933 A5 JP 2023071933A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- disease
- adpr
- condition
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025076718A JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862648585P | 2018-03-27 | 2018-03-27 | |
| US62/648,585 | 2018-03-27 | ||
| US201862693021P | 2018-07-02 | 2018-07-02 | |
| US62/693,021 | 2018-07-02 | ||
| JP2020551992A JP7242696B2 (ja) | 2018-03-27 | 2019-03-26 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| PCT/US2019/023977 WO2019191026A2 (en) | 2018-03-27 | 2019-03-26 | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551992A Division JP7242696B2 (ja) | 2018-03-27 | 2019-03-26 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025076718A Division JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023071933A JP2023071933A (ja) | 2023-05-23 |
| JP2023071933A5 true JP2023071933A5 (https=) | 2023-08-14 |
| JP7745584B2 JP7745584B2 (ja) | 2025-09-29 |
Family
ID=66647439
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551992A Active JP7242696B2 (ja) | 2018-03-27 | 2019-03-26 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2023035224A Active JP7745584B2 (ja) | 2018-03-27 | 2023-03-08 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2025076718A Pending JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551992A Active JP7242696B2 (ja) | 2018-03-27 | 2019-03-26 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025076718A Pending JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US10946034B2 (https=) |
| EP (2) | EP4226971A1 (https=) |
| JP (3) | JP7242696B2 (https=) |
| ES (1) | ES2949441T3 (https=) |
| WO (1) | WO2019191026A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102622656B1 (ko) | 2016-02-18 | 2024-01-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| WO2019191026A2 (en) | 2018-03-27 | 2019-10-03 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
| CN111714619B (zh) * | 2020-07-15 | 2023-03-14 | 上海市浦东新区人民医院 | 成纤维生长因子6在制备缓解非酒精性脂肪性肝炎肝损伤的药物中的应用 |
| CN112972453B (zh) * | 2021-03-05 | 2022-04-15 | 中国人民解放军军事科学院军事医学研究院 | MDL-800在制备抑制SARS-CoV-2病毒易感性药物中的应用 |
| KR102789553B1 (ko) * | 2021-09-07 | 2025-04-03 | 주식회사 펄스인마이어스 | 방사선 및/또는 항암 치료 보조 요법으로 아데노신 디포스페이트 리보오스의 활용 |
| WO2025122455A1 (en) * | 2023-12-04 | 2025-06-12 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) for vegf modulation |
| WO2025259632A1 (en) * | 2024-06-12 | 2025-12-18 | Sirtsei Pharmaceuticals, Inc. | Compositions and methods for treating retinal diseases or conditions |
| WO2026073064A1 (en) * | 2024-09-30 | 2026-04-02 | Invirsa, Inc. | 5'-adenosine diphosphate ribose (adpr) for use in improving visual acuity |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04273826A (ja) * | 1991-02-27 | 1992-09-30 | Dainippon Ink & Chem Inc | 抗ｒｓウイルス剤 |
| EP0618214A1 (en) | 1993-04-01 | 1994-10-05 | Merrell Dow Pharmaceuticals Inc. | Unsaturated phosphonate derivatives of purines and pyrimidines |
| JPH07247210A (ja) | 1994-03-09 | 1995-09-26 | Sunstar Inc | 口腔用組成物 |
| JP2001515916A (ja) | 1997-09-11 | 2001-09-25 | オクシジェン，インコーポレイテッド | 悪性および伝染性疾患の治療用にニコチンアミド・アデニン・ジヌクレオチドならびにその類似物を用いる治療法 |
| WO2000050024A2 (en) | 1999-02-26 | 2000-08-31 | Inspire Pharmaceuticals, Inc. | Method of promoting mucosal hydration with certain uridine, adenine and cytidine diphosphates and analogs thereof |
| EP1192258A2 (en) | 1999-06-16 | 2002-04-03 | Icos Corporation | Human poly(adp-ribose) polymerase 2 materials and methods |
| US6528042B1 (en) | 1999-10-08 | 2003-03-04 | Galileo Laboratories, Inc. | Compositions of flavonoids for use as cytoprotectants and methods of making and using them |
| US7115585B2 (en) | 2000-08-21 | 2006-10-03 | Inspire Pharmaceuticals, Inc. | Compositions for treating epithelial and retinal tissue diseases |
| EP1409503A1 (en) | 2001-07-25 | 2004-04-21 | Celltech R & D Limited | Non-natural carbon-linked nucleotides and dinucleotides |
| AU2003230952A1 (en) | 2002-05-21 | 2003-12-12 | Abbott Laboratories | Treatment of mucositis |
| JP2005089450A (ja) | 2003-08-11 | 2005-04-07 | Fujisawa Pharmaceut Co Ltd | Ｒｓウィルスによる感染症の予防または治療剤 |
| US20070212395A1 (en) | 2006-03-08 | 2007-09-13 | Allergan, Inc. | Ocular therapy using sirtuin-activating agents |
| US20050276762A1 (en) | 2004-06-15 | 2005-12-15 | Tapas Das | Topical compositions containing 5'-adenosine-diphosphate ribose |
| WO2006127987A2 (en) | 2005-05-25 | 2006-11-30 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| EP1948215B1 (en) | 2005-11-14 | 2012-01-11 | Centre National De La Recherche Scientifique (Cnrs) | MacroH2A non-histone domain as inhibitor of PARP-1 activity and uses thereof |
| WO2008154129A1 (en) | 2007-06-08 | 2008-12-18 | Bausch & Lomb Incorporated | Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye |
| US20110217262A1 (en) | 2010-03-05 | 2011-09-08 | Kornfield Julia A | Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability |
| JP2013526514A (ja) | 2010-05-10 | 2013-06-24 | ラディカル・セラピューティックス・インコーポレイテッド | リポ酸およびニトロキシド誘導体およびその使用 |
| KR101967938B1 (ko) | 2011-05-12 | 2019-04-10 | 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 | 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물 |
| US20160287622A1 (en) | 2013-11-18 | 2016-10-06 | Massachusetts Institute Of Technology | Compositions and methods for treating immune and viral disorders and modulating protein-rna interaction |
| KR102622656B1 (ko) * | 2016-02-18 | 2024-01-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| WO2019191026A2 (en) | 2018-03-27 | 2019-10-03 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
-
2019
- 2019-03-26 WO PCT/US2019/023977 patent/WO2019191026A2/en not_active Ceased
- 2019-03-26 EP EP23168073.7A patent/EP4226971A1/en active Pending
- 2019-03-26 JP JP2020551992A patent/JP7242696B2/ja active Active
- 2019-03-26 US US16/364,760 patent/US10946034B2/en active Active
- 2019-03-26 EP EP19726521.8A patent/EP3773604B1/en active Active
- 2019-03-26 ES ES19726521T patent/ES2949441T3/es active Active
-
2021
- 2021-02-09 US US17/171,548 patent/US11793826B2/en active Active
-
2023
- 2023-03-08 JP JP2023035224A patent/JP7745584B2/ja active Active
- 2023-09-11 US US18/244,693 patent/US12233083B2/en active Active
-
2025
- 2025-01-17 US US19/029,481 patent/US20250161343A1/en not_active Abandoned
- 2025-05-02 JP JP2025076718A patent/JP2025118771A/ja active Pending
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