JP2021525245A5 - - Google Patents

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Publication number
JP2021525245A5
JP2021525245A5 JP2020565341A JP2020565341A JP2021525245A5 JP 2021525245 A5 JP2021525245 A5 JP 2021525245A5 JP 2020565341 A JP2020565341 A JP 2020565341A JP 2020565341 A JP2020565341 A JP 2020565341A JP 2021525245 A5 JP2021525245 A5 JP 2021525245A5
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JP
Japan
Prior art keywords
vector
polynucleotide
promoter
use according
aav2
Prior art date
Application number
JP2020565341A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019226832A5 (https=
JP2021525245A (ja
JP7587423B2 (ja
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Priority claimed from PCT/US2019/033616 external-priority patent/WO2019226832A1/en
Publication of JP2021525245A publication Critical patent/JP2021525245A/ja
Publication of JPWO2019226832A5 publication Critical patent/JPWO2019226832A5/ja
Publication of JP2021525245A5 publication Critical patent/JP2021525245A5/ja
Application granted granted Critical
Publication of JP7587423B2 publication Critical patent/JP7587423B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020565341A 2018-05-22 2019-05-22 アルツハイマー病のための遺伝子治療 Active JP7587423B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862675003P 2018-05-22 2018-05-22
US62/675,003 2018-05-22
PCT/US2019/033616 WO2019226832A1 (en) 2018-05-22 2019-05-22 Gene therapy for alzheimer's disease

Publications (4)

Publication Number Publication Date
JP2021525245A JP2021525245A (ja) 2021-09-24
JPWO2019226832A5 JPWO2019226832A5 (https=) 2022-05-26
JP2021525245A5 true JP2021525245A5 (https=) 2022-05-26
JP7587423B2 JP7587423B2 (ja) 2024-11-20

Family

ID=68617210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020565341A Active JP7587423B2 (ja) 2018-05-22 2019-05-22 アルツハイマー病のための遺伝子治療

Country Status (8)

Country Link
US (1) US12497608B2 (https=)
EP (1) EP3796980A4 (https=)
JP (1) JP7587423B2 (https=)
CN (1) CN112739419A (https=)
AU (1) AU2019272848A1 (https=)
CA (1) CA3100946A1 (https=)
IL (1) IL278813A (https=)
WO (1) WO2019226832A1 (https=)

Families Citing this family (7)

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WO2020242892A1 (en) 2019-05-24 2020-12-03 The Brigham And Women's Hospital, Inc. Gene therapy for alzheimer's disease
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WO2022261413A1 (en) * 2021-06-10 2022-12-15 The Brigham And Women’S Hospital, Inc. Cell-based assay for identification of activators of gamma-secretase
EP4399311A4 (en) * 2021-09-10 2025-11-26 Alnylam Pharmaceuticals Inc APP ARNI COMPOSITIONS AND THEIR METHODS OF USE FOR TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ENLARGED ENDOSOMES
CN116024270B (zh) * 2021-12-27 2025-07-22 中国科学院昆明动物研究所 一种app/psen1双转基因阿尔茨海默病树鼩模型的建立方法
CN115125244A (zh) * 2022-05-14 2022-09-30 吉林大学 构建阿尔兹海默症的兔模型方法

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