JP2021521794A5 - - Google Patents
Info
- Publication number
- JP2021521794A5 JP2021521794A5 JP2020557910A JP2020557910A JP2021521794A5 JP 2021521794 A5 JP2021521794 A5 JP 2021521794A5 JP 2020557910 A JP2020557910 A JP 2020557910A JP 2020557910 A JP2020557910 A JP 2020557910A JP 2021521794 A5 JP2021521794 A5 JP 2021521794A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- antisense oligomer
- acceptable salt
- exon
- dystrophin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023202664A JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862663162P | 2018-04-26 | 2018-04-26 | |
| US62/663,162 | 2018-04-26 | ||
| PCT/US2019/028613 WO2019209764A2 (en) | 2018-04-26 | 2019-04-23 | Exon skipping oligomers and oligomer conjugates for muscular dystrophy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202664A Division JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021521794A JP2021521794A (ja) | 2021-08-30 |
| JP2021521794A5 true JP2021521794A5 (enExample) | 2022-04-25 |
Family
ID=68295765
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020557910A Pending JP2021521794A (ja) | 2018-04-26 | 2019-04-23 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
| JP2023202664A Pending JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023202664A Pending JP2024009344A (ja) | 2018-04-26 | 2023-11-30 | 筋ジストロフィーに対するエクソンスキッピングオリゴマーおよびオリゴマーコンジュゲート |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20210102205A1 (enExample) |
| EP (1) | EP3784248A4 (enExample) |
| JP (2) | JP2021521794A (enExample) |
| WO (1) | WO2019209764A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| WO2020028832A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| EP3830259A4 (en) | 2018-08-02 | 2022-05-04 | Dyne Therapeutics, Inc. | MUSCLE TARGETED COMPLEXES AND THEIR USES IN THE TREATMENT OF FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| CA3211038A1 (en) * | 2021-02-12 | 2022-08-18 | Oxford University Innovation Limited | Cell-penetrating peptide conjugates and methods of their use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2627917T3 (es) * | 2004-06-28 | 2017-08-01 | The University Of Western Australia | Oligonucleótidos no codificantes para la inducción de la omisión exónica y métodos de uso de los mismos |
| EP3133160B1 (en) * | 2008-10-24 | 2018-12-12 | Sarepta Therapeutics, Inc. | Exon skipping compositions for dmd |
| TWI541024B (zh) * | 2010-09-01 | 2016-07-11 | 日本新藥股份有限公司 | 反義核酸 |
| AU2011367230B2 (en) * | 2011-05-05 | 2017-08-10 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| WO2013030569A2 (en) * | 2011-08-30 | 2013-03-07 | Michael John Gait | Peptides |
| CN106414739A (zh) * | 2012-12-20 | 2017-02-15 | 萨雷普塔医疗公司 | 用于治疗肌营养不良症的改良的外显子跳跃组合物 |
| EP3760720A1 (en) * | 2013-03-14 | 2021-01-06 | Sarepta Therapeutics, Inc. | Exon skipping compositions for treating muscular dystrophy |
| HK1220154A1 (zh) * | 2013-03-15 | 2017-04-28 | Sarepta Therapeutics, Inc. | 改进的用於治疗肌营养不良的组合物 |
| MX2017011004A (es) * | 2015-02-27 | 2018-02-09 | Sarepta Therapeutics Inc | Inclusion del exon2 inducida por antisentido en alfa-glucosidasa.acida. |
| JP2018530560A (ja) * | 2015-10-09 | 2018-10-18 | サレプタ セラピューティクス， インコーポレイテッド | デュシェンヌ型筋ジストロフィーおよび関連障害の処置のための組成物および方法 |
| MX384727B (es) * | 2016-05-24 | 2025-03-14 | Sarepta Therapeutics Inc | Procesos para preparar oligómeros |
| KR20190024977A (ko) * | 2016-06-30 | 2019-03-08 | 사렙타 쎄러퓨틱스 인코퍼레이티드 | 근육 이상증에 대한 엑손 스킵핑 올리고머 |
-
2019
- 2019-04-23 WO PCT/US2019/028613 patent/WO2019209764A2/en not_active Ceased
- 2019-04-23 JP JP2020557910A patent/JP2021521794A/ja active Pending
- 2019-04-23 EP EP19793325.2A patent/EP3784248A4/en active Pending
- 2019-04-23 US US17/048,163 patent/US20210102205A1/en not_active Abandoned
-
2023
- 2023-11-30 JP JP2023202664A patent/JP2024009344A/ja active Pending
-
2024
- 2024-04-12 US US18/634,360 patent/US20250092393A1/en active Pending
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