JP2021521142A5 - - Google Patents
Info
- Publication number
- JP2021521142A5 JP2021521142A5 JP2020555239A JP2020555239A JP2021521142A5 JP 2021521142 A5 JP2021521142 A5 JP 2021521142A5 JP 2020555239 A JP2020555239 A JP 2020555239A JP 2020555239 A JP2020555239 A JP 2020555239A JP 2021521142 A5 JP2021521142 A5 JP 2021521142A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxo
- chloro
- cyclohexyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862654628P | 2018-04-09 | 2018-04-09 | |
| US62/654,628 | 2018-04-09 | ||
| PCT/JP2019/015392 WO2019198692A1 (en) | 2018-04-09 | 2019-04-09 | Fused cyclic urea derivatives as crhr2 antagonist |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521142A JP2021521142A (ja) | 2021-08-26 |
| JP2021521142A5 true JP2021521142A5 (enExample) | 2023-05-19 |
| JP7357932B2 JP7357932B2 (ja) | 2023-10-10 |
Family
ID=68164246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555239A Active JP7357932B2 (ja) | 2018-04-09 | 2019-04-09 | Ｃｒｈｒ２拮抗薬としての縮合環状尿素誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11802120B2 (enExample) |
| EP (1) | EP3774739B1 (enExample) |
| JP (1) | JP7357932B2 (enExample) |
| KR (1) | KR102590854B1 (enExample) |
| CN (1) | CN111868037B (enExample) |
| BR (1) | BR112020020708A8 (enExample) |
| CA (1) | CA3094609A1 (enExample) |
| ES (1) | ES2917634T3 (enExample) |
| MX (1) | MX2020010568A (enExample) |
| TW (1) | TWI822754B (enExample) |
| WO (1) | WO2019198692A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2865330T3 (es) | 2015-04-29 | 2021-10-15 | Janssen Pharmaceutica Nv | Azabenzimidazoles y su uso como moduladores del receptor AMPA |
| TW202140480A (zh) * | 2020-01-15 | 2021-11-01 | 日商拉夸里亞創藥股份有限公司 | 作為crhr2拮抗劑之螺雜環衍生物 |
| EP3901152A1 (en) * | 2020-04-23 | 2021-10-27 | F. Hoffmann-La Roche AG | Kv3 enhancers for the treatment of cognitive disorders |
| CR20220565A (es) | 2020-05-06 | 2023-01-13 | Merck Sharp & Dohme Llc | Inhibidores de il4i1 y métodos de uso |
| JP2023545256A (ja) | 2020-09-30 | 2023-10-27 | ラクオリア創薬株式会社 | Ｃｒｈｒ２拮抗薬としての３－ヒドロキシオキシインドール誘導体 |
| JP7607799B2 (ja) * | 2021-04-27 | 2024-12-27 | メッドシャイン ディスカバリー インコーポレイテッド | ６員芳香族ヘテロ尿素環の誘導体及びその使用 |
| TW202540088A (zh) * | 2024-01-17 | 2025-10-16 | 南韓商Ｌｇ化學股份有限公司 | 作為ＣＢＰ／ｐ３００抑制劑之新穎化合物和含有彼作為活性成分以預防或治療癌症、發炎病症或自體免疫疾病之醫藥組成物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3538899A (en) * | 1998-04-30 | 1999-11-23 | Nippon Chemiphar Co. Ltd. | Condensed imidazole derivative and therapeutic agent for liver disease |
| DE60225127T2 (de) | 2001-04-30 | 2009-02-19 | Glaxo Group Ltd., Greenford | Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf) |
| EP1395591B1 (en) | 2001-06-12 | 2008-06-04 | Glaxo Group Limited | Corticotropin releasing factor antagonists |
| JP2007161585A (ja) | 2004-06-25 | 2007-06-28 | Taisho Pharmaceut Co Ltd | 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体 |
| US7652035B2 (en) | 2004-10-19 | 2010-01-26 | Neurocrine Bioscience, Inc. | CRF receptor antagonists and methods relating thereto |
| US10166271B2 (en) | 2006-06-21 | 2019-01-01 | The Regents Of The University Of California | Methods for promoting hair growth |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| AR080056A1 (es) * | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| JP5748777B2 (ja) | 2010-02-02 | 2015-07-15 | ノバルティス アーゲー | Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体 |
| US20150094310A1 (en) * | 2012-04-23 | 2015-04-02 | Holsboermaschmeyer Neurochemie Gmbh | Crhr1 antagonists for use in the treatment of patients having crh overactivity |
-
2019
- 2019-04-09 EP EP19785626.3A patent/EP3774739B1/en active Active
- 2019-04-09 KR KR1020207030243A patent/KR102590854B1/ko active Active
- 2019-04-09 ES ES19785626T patent/ES2917634T3/es active Active
- 2019-04-09 TW TW108112345A patent/TWI822754B/zh active
- 2019-04-09 JP JP2020555239A patent/JP7357932B2/ja active Active
- 2019-04-09 CA CA3094609A patent/CA3094609A1/en active Pending
- 2019-04-09 WO PCT/JP2019/015392 patent/WO2019198692A1/en not_active Ceased
- 2019-04-09 US US17/046,196 patent/US11802120B2/en active Active
- 2019-04-09 BR BR112020020708A patent/BR112020020708A8/pt unknown
- 2019-04-09 CN CN201980019725.6A patent/CN111868037B/zh active Active
- 2019-04-09 MX MX2020010568A patent/MX2020010568A/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021521142A5 (enExample) | ||
| JP2017530960A5 (enExample) | ||
| CN111868037B (zh) | 作为crhr2拮抗剂的稠合环状脲衍生物 | |
| HRP20200962T1 (hr) | Novi spojevi | |
| US8987301B2 (en) | Heteroarylaminoquinolines as TGF-beta receptor kinase inhibitors | |
| JP5911638B2 (ja) | ベンゾチアゾール−６−イル酢酸誘導体およびｈｉｖ感染を処置するためのそれらの使用 | |
| RU2015129538A (ru) | Замещенные имидазопиридины в качестве ингибиторов hdm2 | |
| JP5987005B2 (ja) | オレキシン拮抗薬として有用な新規なピラゾール及びイミダゾール誘導体 | |
| JP2020514267A5 (enExample) | ||
| AU2018334290A1 (en) | Pyridazinones and methods of use thereof | |
| RU2016140338A (ru) | Азаспиро производные в качестве антагонистов trpm8 | |
| CA2571627A1 (en) | Substituted aryl-amine derivatives and methods of use | |
| CA2570987A1 (en) | Novel alkynyl derivatives as modulators of metabotropic glutamate receptors | |
| CA2921880A1 (en) | Alkynyl alcohols and methods of use | |
| JP2013519724A5 (enExample) | ||
| JP2018518462A (ja) | アザベンズイミダゾール及びａｍａｐ受容体調節因子としてのその使用 | |
| RU2014119244A (ru) | Гетероциклические соединения и способы их использования | |
| KR20250021398A (ko) | Kif18a 저해용 화합물 | |
| JP2023145748A (ja) | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 | |
| WO2012085857A1 (en) | 3,8-diaza-bicyclo[4.2.0]oct-3-yl amides | |
| HRP20250272T1 (hr) | Derivati benzimidazola i njihova uporaba | |
| TW202342055A (zh) | Raf激酶抑制劑 | |
| JP2021519294A5 (enExample) | ||
| WO2021145401A1 (en) | Spiroheterocyclic derivatives as crhr2 antagonist | |
| RU2020134947A (ru) | Производные конденсированной циклической мочевины в антагонист crhr2 |