JP2021520392A5 - - Google Patents
Info
- Publication number
- JP2021520392A5 JP2021520392A5 JP2020554834A JP2020554834A JP2021520392A5 JP 2021520392 A5 JP2021520392 A5 JP 2021520392A5 JP 2020554834 A JP2020554834 A JP 2020554834A JP 2020554834 A JP2020554834 A JP 2020554834A JP 2021520392 A5 JP2021520392 A5 JP 2021520392A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- triazolo
- pyrazolo
- pyrimidine
- furan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2018/082140 | 2018-04-08 | ||
| CN2018082140 | 2018-04-08 | ||
| PCT/CN2019/081785 WO2019196803A1 (en) | 2018-04-08 | 2019-04-08 | Pyrazolotriazolopyrimidine derivatives as a2a receptor antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021520392A JP2021520392A (ja) | 2021-08-19 |
| JP2021520392A5 true JP2021520392A5 (https=) | 2022-04-07 |
Family
ID=68163465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554834A Withdrawn JP2021520392A (ja) | 2018-04-08 | 2019-04-08 | Ａ２ａ受容体アンタゴニストとしてのピラゾロトリアゾロピリミジン誘導体 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11472811B2 (https=) |
| EP (1) | EP3774813A4 (https=) |
| JP (1) | JP2021520392A (https=) |
| KR (1) | KR20200140849A (https=) |
| CN (1) | CN112313234B (https=) |
| AU (1) | AU2019251148A1 (https=) |
| BR (1) | BR112020020078A2 (https=) |
| CA (1) | CA3095839A1 (https=) |
| EA (1) | EA202092036A1 (https=) |
| IL (1) | IL277744A (https=) |
| MX (1) | MX2020010618A (https=) |
| SG (1) | SG11202009706VA (https=) |
| TW (1) | TW202010500A (https=) |
| WO (1) | WO2019196803A1 (https=) |
| ZA (1) | ZA202005772B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3774813A4 (en) | 2018-04-08 | 2021-11-17 | BeiGene, Ltd. | PYRAZOLOTRIAZOLOPYRIMIDE DERIVATIVES AS A2A RECEPTOR ANTAGONIST |
| KR20230049580A (ko) * | 2020-03-26 | 2023-04-13 | 헵테얼즈 테라퓨틱스 리미티드 | 트리아졸론 화합물 |
| WO2021191376A1 (en) * | 2020-03-26 | 2021-09-30 | Astrazeneca Ab | Triazolone compounds |
| WO2022087146A1 (en) | 2020-10-22 | 2022-04-28 | Landos Biopharma, Inc. | Lancl ligands |
| CN113773327B (zh) * | 2021-09-13 | 2022-07-15 | 八叶草健康产业研究院(厦门)有限公司 | 一种吡唑并嘧啶并三唑环类化合物的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60110219T2 (de) | 2000-05-26 | 2006-03-09 | Schering Corp. | Adenosin a2a rezeptor antagonisten |
| MXPA04003277A (es) | 2001-10-08 | 2004-07-23 | Hoffmann La Roche | Amida del acido 8-amino-?1,2,4?triazolo?1,5-a?piridina-6-carboxilico. |
| US20030139427A1 (en) | 2002-08-23 | 2003-07-24 | Osi Pharmaceuticals Inc. | Bicyclic pyrimidinyl derivatives and methods of use thereof |
| ATE461932T1 (de) | 2004-04-21 | 2010-04-15 | Schering Corp | Pyrazoloä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidine als antagonisten des adenosin-a2a-rezeptors |
| AU2011306358B2 (en) * | 2010-09-24 | 2014-08-14 | Impetis Biosciences Ltd. | Fused tricyclic compounds as adenosine receptor antagonist |
| WO2012135084A1 (en) | 2011-03-31 | 2012-10-04 | Merck Sharp & Dohme Corp. | METABOLITES OF 2-(FURAN-2-YL)-7-(2-(4-(4-(2-METHOXYETHOXY)PHENYL)PIPERAZIN-1-YL)ETHYL)-7H-PYRAZOLO[4,3-e][1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-5-AMINE AND THEIR UTILITY AS ADENOSINE A2a RECEPTOR ANTAGONISTS |
| WO2017136375A1 (en) | 2016-02-05 | 2017-08-10 | Concert Pharmaceuticals, Inc. | Deuterated tozadenant |
| EP3774813A4 (en) | 2018-04-08 | 2021-11-17 | BeiGene, Ltd. | PYRAZOLOTRIAZOLOPYRIMIDE DERIVATIVES AS A2A RECEPTOR ANTAGONIST |
| CN110742893B (zh) | 2018-07-23 | 2024-04-05 | 百济神州(北京)生物科技有限公司 | A2a受体拮抗剂治疗癌症的方法 |
-
2019
- 2019-04-08 EP EP19785064.7A patent/EP3774813A4/en not_active Withdrawn
- 2019-04-08 US US16/982,681 patent/US11472811B2/en active Active
- 2019-04-08 AU AU2019251148A patent/AU2019251148A1/en not_active Abandoned
- 2019-04-08 CN CN201980024422.3A patent/CN112313234B/zh not_active Expired - Fee Related
- 2019-04-08 BR BR112020020078-6A patent/BR112020020078A2/pt not_active IP Right Cessation
- 2019-04-08 EA EA202092036A patent/EA202092036A1/ru unknown
- 2019-04-08 MX MX2020010618A patent/MX2020010618A/es unknown
- 2019-04-08 WO PCT/CN2019/081785 patent/WO2019196803A1/en not_active Ceased
- 2019-04-08 TW TW108112189A patent/TW202010500A/zh unknown
- 2019-04-08 CA CA3095839A patent/CA3095839A1/en active Pending
- 2019-04-08 JP JP2020554834A patent/JP2021520392A/ja not_active Withdrawn
- 2019-04-08 KR KR1020207031434A patent/KR20200140849A/ko not_active Ceased
- 2019-04-08 SG SG11202009706VA patent/SG11202009706VA/en unknown
-
2020
- 2020-09-17 ZA ZA2020/05772A patent/ZA202005772B/en unknown
- 2020-10-01 IL IL277744A patent/IL277744A/en unknown
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