JP2021516674A5 - - Google Patents
Info
- Publication number
- JP2021516674A5 JP2021516674A5 JP2020544501A JP2020544501A JP2021516674A5 JP 2021516674 A5 JP2021516674 A5 JP 2021516674A5 JP 2020544501 A JP2020544501 A JP 2020544501A JP 2020544501 A JP2020544501 A JP 2020544501A JP 2021516674 A5 JP2021516674 A5 JP 2021516674A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- group
- substituted
- cancer
- alkyl
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862634656P | 2018-02-23 | 2018-02-23 | |
| US62/634,656 | 2018-02-23 | ||
| PCT/US2019/019129 WO2019165192A1 (en) | 2018-02-23 | 2019-02-22 | 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021516674A JP2021516674A (ja) | 2021-07-08 |
| JP2021516674A5 true JP2021516674A5 (https=) | 2022-02-24 |
| JPWO2019165192A5 JPWO2019165192A5 (https=) | 2022-02-24 |
| JP7369132B2 JP7369132B2 (ja) | 2023-10-25 |
Family
ID=65812386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544501A Active JP7369132B2 (ja) | 2018-02-23 | 2019-02-22 | ５－ヘテロアリール置換イミダゾール－３－カルボキサミドならびにその調製および使用の方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10934297B2 (https=) |
| EP (1) | EP3755696B1 (https=) |
| JP (1) | JP7369132B2 (https=) |
| KR (1) | KR102861944B1 (https=) |
| CN (1) | CN112020501A (https=) |
| AU (1) | AU2019224075A1 (https=) |
| BR (1) | BR112020017087A2 (https=) |
| CA (1) | CA3091913A1 (https=) |
| CL (1) | CL2020002177A1 (https=) |
| EA (1) | EA202092002A1 (https=) |
| ES (1) | ES2945558T3 (https=) |
| IL (1) | IL276814A (https=) |
| MA (1) | MA51908A (https=) |
| MX (1) | MX2020008852A (https=) |
| PE (1) | PE20211447A1 (https=) |
| PH (1) | PH12020551300A1 (https=) |
| SG (1) | SG11202008029UA (https=) |
| WO (1) | WO2019165192A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019224075A1 (en) | 2018-02-23 | 2020-09-10 | Samumed, Llc | 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof |
| PT3790873T (pt) * | 2018-05-07 | 2022-05-11 | Acraf | Compostos de 1h-indazole-3-carboxamida como inibidores da glicogénio sintase cinase 3 beta |
| JP7444458B2 (ja) * | 2018-09-21 | 2024-03-06 | 学校法人福岡大学 | プリオン病治療薬 |
| JP2023506257A (ja) * | 2019-12-16 | 2023-02-15 | コリア リサーチ インスティチュート オブ ケミカル テクノロジー | 新規なインダゾール誘導体及びその用途 |
| WO2021120890A1 (en) | 2019-12-20 | 2021-06-24 | Novartis Ag | Pyrazolyl derivatives useful as anti-cancer agents |
| AU2024301960A1 (en) * | 2023-06-14 | 2026-01-22 | Prothena Biosciences Limited | Bicyclic heteroaromatic compounds for treating neurological disorders |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4164559A (en) | 1977-09-21 | 1979-08-14 | Cornell Research Foundation, Inc. | Collagen drug delivery device |
| US4474752A (en) | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| US6440102B1 (en) | 1998-07-23 | 2002-08-27 | Durect Corporation | Fluid transfer and diagnostic system for treating the inner ear |
| DE19853299C2 (de) | 1998-11-19 | 2003-04-03 | Thomas Lenarz | Katheter zur Applikation von Medikamenten in Flüssigkeitsräumen des menschlichen Innenohrs |
| US6120484A (en) | 1999-02-17 | 2000-09-19 | Silverstein; Herbert | Otological implant for delivery of medicament and method of using same |
| US6967023B1 (en) | 2000-01-10 | 2005-11-22 | Foamix, Ltd. | Pharmaceutical and cosmetic carrier or composition for topical application |
| YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| US6648873B2 (en) | 2001-09-21 | 2003-11-18 | Durect Corp. | Aural catheter system including anchor balloon and balloon inflation device |
| GB0218625D0 (en) * | 2002-08-10 | 2002-09-18 | Astex Technology Ltd | Pharmaceutical compounds |
| MXPA05003317A (es) | 2002-09-25 | 2005-07-05 | Memory Pharm Corp | Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos. |
| FR2845382A1 (fr) | 2002-10-02 | 2004-04-09 | Sanofi Synthelabo | Derives d'indazolecarboxamides, leur preparation et leur utilisation en therapeutique |
| US7008953B2 (en) | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| FR2867778B1 (fr) * | 2004-03-16 | 2006-06-09 | Sanofi Synthelabo | Utilisation de derives d'indazolecarboxamides pour la preparation d'un medicament destine au traitement et a la prevention du paludisme |
| NZ550534A (en) | 2004-03-25 | 2009-07-31 | Memory Pharm Corp | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
| UA93348C2 (ru) * | 2004-03-25 | 2011-02-10 | Меморі Фармас'Ютікалз Корпорейшн | Индазолы, бензотиазолы, бензоизотиазолы, их получение и применение |
| WO2011050245A1 (en) * | 2009-10-23 | 2011-04-28 | Yangbo Feng | Bicyclic heteroaryls as kinase inhibitors |
| CN103889976A (zh) * | 2011-08-12 | 2014-06-25 | 弗·哈夫曼-拉罗切有限公司 | 吲唑化合物、组合物及使用方法 |
| EP3473099A1 (en) * | 2011-09-14 | 2019-04-24 | Samumed, LLC | Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors |
| CA2860250C (en) * | 2012-02-21 | 2020-11-10 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | 1h-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors |
| PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
| MX2016012208A (es) * | 2014-03-20 | 2017-01-26 | Samumed Llc | Indazol-3-carboxamidas 5-substituidas y preparacion y uso de las mismas. |
| WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
| BR112018009252A2 (pt) | 2015-11-06 | 2018-11-06 | Samumed Llc | tratamento da osteoartrite |
| LT3464285T (lt) | 2016-06-01 | 2022-12-27 | Biosplice Therapeutics, Inc. | N-(5-(3-(7-(3-fluorfenil)-3h-imidazo[4,5-c]piridin-2-il)-1h-indazol-5-il)piridin-3-il)- 3-metilbutanamido gamybos būdas |
| CN110709082A (zh) * | 2016-10-21 | 2020-01-17 | 萨穆梅德有限公司 | 吲唑-3-甲酰胺的使用方法及其作为Wnt/β-连环蛋白信号传导途径抑制剂的用途 |
| AU2019224075A1 (en) | 2018-02-23 | 2020-09-10 | Samumed, Llc | 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof |
-
2019
- 2019-02-22 AU AU2019224075A patent/AU2019224075A1/en not_active Abandoned
- 2019-02-22 BR BR112020017087-9A patent/BR112020017087A2/pt not_active IP Right Cessation
- 2019-02-22 PE PE2020001271A patent/PE20211447A1/es unknown
- 2019-02-22 MA MA051908A patent/MA51908A/fr unknown
- 2019-02-22 EA EA202092002A patent/EA202092002A1/ru unknown
- 2019-02-22 US US16/283,366 patent/US10934297B2/en active Active
- 2019-02-22 CN CN201980027314.1A patent/CN112020501A/zh active Pending
- 2019-02-22 JP JP2020544501A patent/JP7369132B2/ja active Active
- 2019-02-22 ES ES19711736T patent/ES2945558T3/es active Active
- 2019-02-22 CA CA3091913A patent/CA3091913A1/en active Pending
- 2019-02-22 MX MX2020008852A patent/MX2020008852A/es unknown
- 2019-02-22 EP EP19711736.9A patent/EP3755696B1/en active Active
- 2019-02-22 KR KR1020207027174A patent/KR102861944B1/ko active Active
- 2019-02-22 WO PCT/US2019/019129 patent/WO2019165192A1/en not_active Ceased
- 2019-02-22 SG SG11202008029UA patent/SG11202008029UA/en unknown
-
2020
- 2020-08-19 IL IL276814A patent/IL276814A/en unknown
- 2020-08-20 PH PH12020551300A patent/PH12020551300A1/en unknown
- 2020-08-24 CL CL2020002177A patent/CL2020002177A1/es unknown
- 2020-12-30 US US17/138,098 patent/US11713320B2/en active Active
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