JP2021513999A5 - - Google Patents
Info
- Publication number
- JP2021513999A5 JP2021513999A5 JP2020544445A JP2020544445A JP2021513999A5 JP 2021513999 A5 JP2021513999 A5 JP 2021513999A5 JP 2020544445 A JP2020544445 A JP 2020544445A JP 2020544445 A JP2020544445 A JP 2020544445A JP 2021513999 A5 JP2021513999 A5 JP 2021513999A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- dose
- composition according
- itrs
- adjacent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023207938A JP2024028931A (ja) | 2018-02-22 | 2023-12-08 | 閉端ｄｎａ（ｃｅｄｎａ）ベクターを使用した導入遺伝子の制御された発現 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862633882P | 2018-02-22 | 2018-02-22 | |
| US201862633795P | 2018-02-22 | 2018-02-22 | |
| US201862633757P | 2018-02-22 | 2018-02-22 | |
| US62/633,882 | 2018-02-22 | ||
| US62/633,795 | 2018-02-22 | ||
| US62/633,757 | 2018-02-22 | ||
| US201862746762P | 2018-10-17 | 2018-10-17 | |
| US62/746,762 | 2018-10-17 | ||
| PCT/US2019/018927 WO2019165050A1 (en) | 2018-02-22 | 2019-02-21 | Controlled expression of transgenes using close-ended dna (cedna) vectors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023207938A Division JP2024028931A (ja) | 2018-02-22 | 2023-12-08 | 閉端ｄｎａ（ｃｅｄｎａ）ベクターを使用した導入遺伝子の制御された発現 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021513999A JP2021513999A (ja) | 2021-06-03 |
| JP2021513999A5 true JP2021513999A5 (https=) | 2022-03-01 |
Family
ID=67687406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544445A Pending JP2021513999A (ja) | 2018-02-22 | 2019-02-21 | 閉端ｄｎａ（ｃｅｄｎａ）ベクターを使用した導入遺伝子の制御された発現 |
| JP2023207938A Pending JP2024028931A (ja) | 2018-02-22 | 2023-12-08 | 閉端ｄｎａ（ｃｅｄｎａ）ベクターを使用した導入遺伝子の制御された発現 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023207938A Pending JP2024028931A (ja) | 2018-02-22 | 2023-12-08 | 閉端ｄｎａ（ｃｅｄｎａ）ベクターを使用した導入遺伝子の制御された発現 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220175970A1 (https=) |
| EP (1) | EP3755803A4 (https=) |
| JP (2) | JP2021513999A (https=) |
| KR (1) | KR20200124250A (https=) |
| CN (1) | CN111886343A (https=) |
| AU (1) | AU2019225937A1 (https=) |
| BR (1) | BR112020017060A2 (https=) |
| CA (1) | CA3092059A1 (https=) |
| IL (1) | IL276658A (https=) |
| MA (1) | MA51915A (https=) |
| MX (1) | MX2020008676A (https=) |
| PH (1) | PH12020551235A1 (https=) |
| SG (1) | SG11202007621TA (https=) |
| WO (1) | WO2019165050A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ762100A (en) | 2017-08-09 | 2025-12-19 | Bioverativ Therapeutics Inc | Nucleic acid molecules and uses thereof |
| EP3833766A1 (en) | 2018-08-09 | 2021-06-16 | Bioverativ Therapeutics Inc. | Nucleic acid molecules and uses thereof for non-viral gene therapy |
| KR20210090619A (ko) * | 2018-11-09 | 2021-07-20 | 제너레이션 바이오 컴퍼니 | 대칭인 변형된 역말단반복을 포함하는 변형된 폐쇄형 DNA(ceDNA) |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| JP2023520763A (ja) * | 2020-03-24 | 2023-05-19 | ジェネレーション バイオ カンパニー | ゴーシェ治療薬を発現するための非ウイルス性ｄｎａベクター及びその使用 |
| US20230138409A1 (en) * | 2020-03-24 | 2023-05-04 | Generation Bio Co. | Non-viral dna vectors and uses thereof for expressing factor ix therapeutics |
| EP4142758A4 (en) * | 2020-04-28 | 2025-02-26 | President and Fellows of Harvard College | High efficiency gene delivery system |
| IL299422A (en) * | 2020-06-26 | 2023-02-01 | Univ Leland Stanford Junior | Targeting the human ccr5 locus as a safe harbor for the expression of therapeutic proteins |
| JP2023535632A (ja) | 2020-07-27 | 2023-08-18 | アンジャリウム バイオサイエンシズ エージー | Ｄｎａ分子の組成物、その作製方法、及びその使用方法 |
| WO2022046665A1 (en) * | 2020-08-23 | 2022-03-03 | Bioverativ Therapeutics Inc. | MODIFIED BACULOVIRUS SYSTEM FOR IMPROVED PRODUCTION OF CLOSED-ENDED DNA (ceDNA) |
| EP4214309A4 (en) * | 2020-09-16 | 2025-07-16 | Generation Bio Co | CLOSED-END DNA VECTORS AND RELATED USES FOR EXPRESSING PHENYLALANINE HYDROXYLASE (PAH) |
| CA3211687A1 (en) * | 2021-03-19 | 2022-09-22 | Ozan ALKAN | Non-viral dna vectors and uses thereof for expressing pfic therapeutics |
| WO2025114932A1 (en) * | 2023-11-30 | 2025-06-05 | Sanofi | Purification of closed-ended dna molecules |
| CN121662213B (zh) * | 2026-02-06 | 2026-04-21 | 湖南博极生命科技有限公司 | 基于注意力权重追溯的中药活性成分可解释性分析方法及系统 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003237805A1 (en) * | 2002-04-09 | 2003-10-27 | Cornell Research Foundation, Inc. | Use of aav integration efficiency element for mediating site-specific integration of a transcription unit |
| HUE041875T2 (hu) * | 2005-05-31 | 2019-06-28 | Univ Colorado Regents | Eljárás génbejuttatásra |
| ES2426091T3 (es) * | 2007-09-19 | 2013-10-21 | Uniqure Ip B.V. | Uso de maquinaria de replicación de AAV para producción de proteína mejorada |
| EP2500434A1 (en) * | 2011-03-12 | 2012-09-19 | Association Institut de Myologie | Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery |
| EP3151866B1 (en) * | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| JP7242180B2 (ja) * | 2014-09-07 | 2023-03-20 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物 |
| EP3889260A1 (en) * | 2014-12-12 | 2021-10-06 | The Broad Institute, Inc. | Protected guide rnas (pgrnas) |
| MX2018010633A (es) * | 2016-03-03 | 2019-06-13 | Univ Massachusetts | Acido desoxirribonucleico (adn) lineal duplex de extremos cerrados para transferencia genica no viral. |
-
2019
- 2019-02-21 MA MA051915A patent/MA51915A/fr unknown
- 2019-02-21 SG SG11202007621TA patent/SG11202007621TA/en unknown
- 2019-02-21 JP JP2020544445A patent/JP2021513999A/ja active Pending
- 2019-02-21 BR BR112020017060-7A patent/BR112020017060A2/pt not_active Application Discontinuation
- 2019-02-21 US US16/971,016 patent/US20220175970A1/en active Pending
- 2019-02-21 EP EP19757005.4A patent/EP3755803A4/en active Pending
- 2019-02-21 KR KR1020207026566A patent/KR20200124250A/ko not_active Ceased
- 2019-02-21 MX MX2020008676A patent/MX2020008676A/es unknown
- 2019-02-21 AU AU2019225937A patent/AU2019225937A1/en not_active Abandoned
- 2019-02-21 CN CN201980019861.5A patent/CN111886343A/zh active Pending
- 2019-02-21 CA CA3092059A patent/CA3092059A1/en active Pending
- 2019-02-21 PH PH1/2020/551235A patent/PH12020551235A1/en unknown
- 2019-02-21 WO PCT/US2019/018927 patent/WO2019165050A1/en not_active Ceased
-
2020
- 2020-08-11 IL IL276658A patent/IL276658A/en unknown
-
2023
- 2023-12-08 JP JP2023207938A patent/JP2024028931A/ja active Pending
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