JP2021512913A5 - - Google Patents

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Publication number
JP2021512913A5
JP2021512913A5 JP2020542775A JP2020542775A JP2021512913A5 JP 2021512913 A5 JP2021512913 A5 JP 2021512913A5 JP 2020542775 A JP2020542775 A JP 2020542775A JP 2020542775 A JP2020542775 A JP 2020542775A JP 2021512913 A5 JP2021512913 A5 JP 2021512913A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
alkoxybenzo
membered heterocyclic
heterocyclic amine
amine compound
Prior art date
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Application number
JP2020542775A
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English (en)
Japanese (ja)
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JP7475049B2 (ja
JP2021512913A (ja
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Publication date
Priority claimed from CN201810124854.9A external-priority patent/CN110117278B/zh
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Publication of JP2021512913A publication Critical patent/JP2021512913A/ja
Publication of JP2021512913A5 publication Critical patent/JP2021512913A5/ja
Application granted granted Critical
Publication of JP7475049B2 publication Critical patent/JP7475049B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020542775A 2018-02-07 2019-01-21 アルコキシベンゾ五員(六員)複素環式アミン化合物およびその医薬用途 Active JP7475049B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201810124854.9 2018-02-07
CN201810124854.9A CN110117278B (zh) 2018-02-07 2018-02-07 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途
PCT/CN2019/072468 WO2019154047A1 (zh) 2018-02-07 2019-01-21 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途

Publications (3)

Publication Number Publication Date
JP2021512913A JP2021512913A (ja) 2021-05-20
JP2021512913A5 true JP2021512913A5 (enExample) 2023-01-10
JP7475049B2 JP7475049B2 (ja) 2024-04-26

Family

ID=67519628

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542775A Active JP7475049B2 (ja) 2018-02-07 2019-01-21 アルコキシベンゾ五員(六員)複素環式アミン化合物およびその医薬用途

Country Status (5)

Country Link
US (1) US11396504B2 (enExample)
EP (1) EP3750890B1 (enExample)
JP (1) JP7475049B2 (enExample)
CN (1) CN110117278B (enExample)
WO (1) WO2019154047A1 (enExample)

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Publication number Priority date Publication date Assignee Title
RU2764243C2 (ru) 2017-09-22 2022-01-14 ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи Гетероциклические соединения в качестве ингибиторов PAD
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
US11629135B2 (en) 2017-11-06 2023-04-18 Jubilant Prodell Llc Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
RS65576B1 (sr) 2017-11-24 2024-06-28 Jubilant Episcribe Llc Heterociklična jedinjenja kao inhibitori prmt5
CN110117278B (zh) 2018-02-07 2022-07-19 石家庄以岭药业股份有限公司 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途
CN112105610B (zh) 2018-03-13 2024-01-26 朱比连特普罗德尔有限责任公司 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物
CN111481548A (zh) * 2019-01-29 2020-08-04 复旦大学 4-(2,6-二氯苄氧基)-3-(3-氨基吡啶)苯并[d]异噁唑在制药中的用途
CN113616652A (zh) * 2020-05-06 2021-11-09 石家庄以岭药业股份有限公司 Sms2抑制剂在制备治疗高侵袭性乳腺癌药物中的应用
CN116854670B (zh) * 2022-03-28 2026-06-02 中国科学院上海药物研究所 一类二氢喹喔啉类选择性溴结构域识别蛋白抑制剂及其制备方法和用途
CN119320385A (zh) * 2023-07-17 2025-01-17 复旦大学 烷氧基噻吩甲酰芳胺类化合物及其应用

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US3755332A (en) * 1971-07-01 1973-08-28 Ciba Geigy Corp Substituted 4 indazolaminoquinolines
US5668154A (en) * 1995-06-06 1997-09-16 Hoechst Marion Roussel Inc. Pyridiniminyl-1,2-benzisoxazoles and -benzisothiazoles
ES2157442T3 (es) * 1995-06-06 2001-08-16 Aventis Pharma Inc Derivados de benzoisoxazol y de indazol, utilizados como agentes neurolepticos.
GB9914486D0 (en) * 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
KR20060114022A (ko) * 2004-02-27 2006-11-03 에프. 호프만-라 로슈 아게 인다졸 유도체 및 그들을 함유하는 약학 조성물
EP1647549A1 (en) * 2004-10-14 2006-04-19 Laboratoire Theramex Indazoles, benzisoxazoles and benzisothiazoles as estrogenic agents
JP5314244B2 (ja) * 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
CA2599992A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. Acridine and quinoline dervatives as sirtuin modulators
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DE102005026194A1 (de) * 2005-06-06 2006-12-07 Grünenthal GmbH Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
EP1899322B1 (en) * 2005-06-28 2009-09-02 Sanofi-Aventis Isoquinoline derivatives as inhibitors of rho-kinase
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JP2010111624A (ja) * 2008-11-06 2010-05-20 Shionogi & Co Ltd Ttk阻害作用を有するインダゾール誘導体
CN101993382B (zh) * 2009-08-21 2014-10-29 复旦大学 芳香胺类衍生物或其类似物及其应用
CN105348182B (zh) 2014-08-24 2018-04-13 复旦大学 2‑烷氧基苯甲酰芳胺类化合物及其药物用途
JP6661192B2 (ja) 2016-01-19 2020-03-11 国立大学法人北海道大学 Sms2阻害活性を有するセラミド誘導体
CN110117278B (zh) 2018-02-07 2022-07-19 石家庄以岭药业股份有限公司 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途

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