|
US4196265A
(en)
|
1977-06-15 |
1980-04-01 |
The Wistar Institute |
Method of producing antibodies
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IE66494B1
(en)
|
1989-09-26 |
1996-01-10 |
Immunex Corp |
Granulocyte-colony stimulating factor receptors
|
|
ES2259800T3
(es)
|
1990-06-11 |
2006-10-16 |
Gilead Sciences, Inc. |
Procedimientos de uso de ligandos de acido nucleico.
|
|
US5270163A
(en)
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
AU3691093A
(en)
|
1992-04-14 |
1993-10-21 |
Hybritech Incorporated |
Methods of inhibiting the growth of multidrug resistant tumors
|
|
DK1621554T4
(da)
|
1992-08-21 |
2012-12-17 |
Univ Bruxelles |
Immunoglobuliner blottet for lette kæder
|
|
US5844094A
(en)
|
1992-09-25 |
1998-12-01 |
Commonwealth Scientific And Industrial Research Organization |
Target binding polypeptide
|
|
AUPM375194A0
(en)
|
1994-02-08 |
1994-03-03 |
Ludwig Institute For Cancer Research |
Cytokine receptor interactive molecules
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
ES2294799T3
(es)
|
1996-06-27 |
2008-04-01 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. |
Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
|
|
DE19742706B4
(de)
|
1997-09-26 |
2013-07-25 |
Pieris Proteolab Ag |
Lipocalinmuteine
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
AUPP221098A0
(en)
|
1998-03-06 |
1998-04-02 |
Diatech Pty Ltd |
V-like domain binding molecules
|
|
CN101818145A
(zh)
|
1998-03-20 |
2010-09-01 |
联邦科学和工业研究组织 |
控制基因表达
|
|
CN1202246C
(zh)
|
1998-04-08 |
2005-05-18 |
联邦科学和工业研究组织 |
获得修饰表型的方法和措施
|
|
NZ507557A
(en)
|
1998-05-06 |
2003-10-31 |
Genentech Inc |
Protein purification by ion exchange chromatography
|
|
AU776910B2
(en)
|
1998-12-08 |
2004-09-23 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Modifying protein immunogenicity
|
|
US7115396B2
(en)
|
1998-12-10 |
2006-10-03 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
JP2000319298A
(ja)
|
1999-03-04 |
2000-11-21 |
Seibutsu Bunshi Kogaku Kenkyusho:Kk |
蛋白質複合体の結晶、構造座標、及び構造座標の使用
|
|
US6326193B1
(en)
|
1999-11-05 |
2001-12-04 |
Cambria Biosciences, Llc |
Insect control agent
|
|
US7108852B2
(en)
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
EP1332209B1
(en)
|
2000-09-08 |
2009-11-11 |
Universität Zürich |
Collections of repeat proteins comprising repeat modules
|
|
US7083784B2
(en)
|
2000-12-12 |
2006-08-01 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
|
US8178098B2
(en)
|
2001-04-03 |
2012-05-15 |
National Jewish Health |
Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies
|
|
US20030082630A1
(en)
|
2001-04-26 |
2003-05-01 |
Maxygen, Inc. |
Combinatorial libraries of monomer domains
|
|
AUPR544401A0
(en)
|
2001-06-04 |
2001-06-28 |
Bischof, Robert Juergen |
Animal model for allergy
|
|
US7501494B2
(en)
|
2003-01-15 |
2009-03-10 |
United Biomedical, Inc. |
Designed deimmunized monoclonal antibodies for protection against HIV exposure and treatment of HIV infection
|
|
JP2006526414A
(ja)
|
2003-06-02 |
2006-11-24 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
脱免疫化抗ｃｄ３抗体
|
|
CA2531238C
(en)
|
2003-07-04 |
2015-02-24 |
Affibody Ab |
Polypeptides having binding affinity for her2
|
|
WO2005019255A1
(en)
|
2003-08-25 |
2005-03-03 |
Pieris Proteolab Ag |
Muteins of tear lipocalin
|
|
US7220407B2
(en)
*
|
2003-10-27 |
2007-05-22 |
Amgen Inc. |
G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
|
|
EP1711196A4
(en)
|
2003-12-05 |
2011-09-14 |
Bristol Myers Squibb Co |
INHIBITORS OF TYPE-2 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS
|
|
JP2008511286A
(ja)
|
2004-06-02 |
2008-04-17 |
ダイアテック・ピーティワイ・リミテッド |
サメ類のＩｇＮＡＲドメインに基づく結合成分
|
|
EP1810979B1
(en)
|
2004-09-22 |
2012-06-20 |
Kyowa Hakko Kirin Co., Ltd. |
STABILIZED HUMAN IgG4 ANTIBODIES
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
EP1924606A4
(en)
*
|
2005-08-25 |
2010-01-13 |
Repair Technologies Inc |
DEVICES, COMPOSITIONS AND METHODS FOR PROTECTING AND REPAIRING CELLS AND TISSUE
|
|
US8455435B2
(en)
*
|
2006-04-19 |
2013-06-04 |
Ludwig-Maximilians-Universitat Munchen |
Remedies for ischemia
|
|
AU2007271163B2
(en)
|
2006-07-06 |
2012-08-23 |
Merck Serono Sa |
CSF3R polypeptides and uses thereof
|
|
PL2056858T3
(pl)
*
|
2006-08-11 |
2015-01-30 |
Csl Ltd |
Leczenie stanów chorobowych płuc
|
|
US20080199426A1
(en)
*
|
2007-01-11 |
2008-08-21 |
Sukhatme Vikas P |
Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders
|
|
US7618938B2
(en)
*
|
2007-02-07 |
2009-11-17 |
Academia Sinica |
Treating cerebrovascular diseases with erythropoietin and granulocyte-colony stimulating factor jointly
|
|
CL2008002782A1
(es)
*
|
2007-09-21 |
2009-07-31 |
Genentech Inc |
Anticuerpo anti-bv8 neutralizante; composicion que lo comprende; y su uso para tratar tumores en humanos previamente tratados con un antagonista del factor de crecimiento endotelial vascular.
|
|
DK2786762T3
(da)
|
2008-12-19 |
2019-05-06 |
Macrogenics Inc |
Kovalente diabodies og anvendelser deraf
|
|
JP2012515556A
(ja)
|
2009-01-23 |
2012-07-12 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
低下したエフェクタ機能を有する安定化Ｆｃポリペプチドおよび使用方法
|
|
WO2011032204A1
(en)
|
2009-09-15 |
2011-03-24 |
Csl Limited |
Treatment of neurological conditions
|
|
US8968731B2
(en)
|
2009-10-09 |
2015-03-03 |
Csl Limited |
Treatment of uveitis
|
|
EP2493921B1
(en)
|
2009-10-30 |
2018-09-26 |
Albumedix Ltd |
Albumin variants
|
|
KR20130020765A
(ko)
|
2010-02-16 |
2013-02-28 |
메디뮨 엘엘씨 |
Ｈｓａ-관련 조성물 및 사용방법
|
|
EP2367000A1
(en)
|
2010-03-04 |
2011-09-21 |
Charité Universitätsmedizin Berlin |
High throughput analysis of T-cell receptor repertoires
|
|
RU2612884C2
(ru)
|
2010-04-02 |
2017-03-13 |
Курна, Инк. |
Лечение заболеваний, связанных с колониестимулирующим фактором 3 (csf3), путем ингибирования природного антисмыслового транскрипта k csf3
|
|
WO2012058479A2
(en)
|
2010-10-27 |
2012-05-03 |
Celldex Therapeutics, Inc. |
Method of improving transplant function using soluble complement receptor type i (scr1)
|
|
CN103379915A
(zh)
|
2011-02-15 |
2013-10-30 |
米迪缪尼有限公司 |
Hsa相关组合物及使用方法
|
|
EP2718326B1
(en)
*
|
2011-06-13 |
2020-08-19 |
CSL Limited |
Antibodies against g-csfr and uses thereof
|
|
EP2780364A2
(en)
|
2011-11-18 |
2014-09-24 |
Eleven Biotherapeutics, Inc. |
Proteins with improved half-life and other properties
|
|
US9050305B2
(en)
*
|
2012-03-29 |
2015-06-09 |
Chs Pharma, Inc. |
Treatment for ischemic stroke
|
|
MX2015005363A
(es)
|
2012-11-08 |
2015-11-06 |
Novozymes Biopharma Dk As |
Variantes de albumina.
|
|
WO2014179657A1
(en)
|
2013-05-03 |
2014-11-06 |
Eleven Biotherapeutics, Inc. |
Albumin variants binding to fcrn
|
|
KR101977449B1
(ko)
|
2013-11-01 |
2019-05-10 |
유니버시티에트 이 오슬로 |
알부민 변이체 및 이의 용도
|
|
UA117608C2
(uk)
|
2014-02-21 |
2018-08-27 |
Дженентек, Інк. |
Спосіб лікування еозинофільного захворювання у пацієнта шляхом застосування біспецифічного анти-il-13/il-17 антитіла
|
|
CN107106681B
(zh)
*
|
2014-11-17 |
2021-11-09 |
Csl有限公司 |
治疗或预防中风的方法
|
|
CA3020988A1
(en)
*
|
2016-04-21 |
2017-10-26 |
Csl Limited |
Method of treating or preventing liver conditions
|
|
US20210179721A1
(en)
|
2017-11-29 |
2021-06-17 |
Csl Limited |
Method of treating or preventing ischemia-reperfusion injury
|
|
KR20190073917A
(ko)
|
2017-12-19 |
2019-06-27 |
포항공과대학교 산학협력단 |
인터류킨-17 억제제 및 종양괴사인자-알파 억제제를 유효성분으로 포함하는 호중구성 폐 염증질환의 예방 또는 치료용 약학적 조성물
|
|
US12281160B2
(en)
|
2018-03-23 |
2025-04-22 |
Csl Limited |
Method of treating asthma
|
|
DK4364724T3
(da)
|
2018-05-10 |
2025-12-22 |
Regeneron Pharma |
Formuleringer med høj koncentration af VEGF-receptorfusionsprotein
|
|
EP3876990A4
(en)
|
2018-11-07 |
2023-09-06 |
Merck Sharp & Dohme LLC |
CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES
|
|
BR112021010920A2
(pt)
|
2018-12-04 |
2021-08-31 |
CSL Innovation Pty Ltd |
Método de tratamento de condições neutrofílicas
|
|
KR20220019806A
(ko)
|
2019-06-12 |
2022-02-17 |
씨에스엘 이노베이션 피티와이 엘티디 |
가용성 보체 수용체 1형 변이체 접합체 및 이의 용도
|