JP2021503029A - 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法 - Google Patents

抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法 Download PDF

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JP2021503029A
JP2021503029A JP2020526569A JP2020526569A JP2021503029A JP 2021503029 A JP2021503029 A JP 2021503029A JP 2020526569 A JP2020526569 A JP 2020526569A JP 2020526569 A JP2020526569 A JP 2020526569A JP 2021503029 A JP2021503029 A JP 2021503029A
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amine
superbranched
acrylate
group
hyperbranched
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JP2021503029A5 (enExample
Inventor
エイチ． シェーンフィッシュ，マーク
エイチ． シェーンフィッシュ，マーク
ヤング，レイ
ジン，ハイバオ
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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Publication of JP2021503029A5 publication Critical patent/JP2021503029A5/ja
Priority to JP2025023232A priority Critical patent/JP2025084800A/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/005—Hyperbranched macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/005—Hyperbranched macromolecules
    • C08G83/006—After treatment of hyperbranched macromolecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polyamides (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Dental Prosthetics (AREA)
JP2020526569A 2017-11-15 2018-11-14 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法 Pending JP2021503029A (ja)

Priority Applications (1)

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JP2025023232A JP2025084800A (ja) 2017-11-15 2025-02-17 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762586404P 2017-11-15 2017-11-15
US62/586,404 2017-11-15
US201862737603P 2018-09-27 2018-09-27
US62/737,603 2018-09-27
PCT/US2018/061061 WO2019099525A1 (en) 2017-11-15 2018-11-14 Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto

Related Child Applications (1)

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JP2025023232A Division JP2025084800A (ja) 2017-11-15 2025-02-17 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法

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JP2021503029A true JP2021503029A (ja) 2021-02-04
JP2021503029A5 JP2021503029A5 (enExample) 2022-01-04

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JP2020526569A Pending JP2021503029A (ja) 2017-11-15 2018-11-14 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法
JP2025023232A Abandoned JP2025084800A (ja) 2017-11-15 2025-02-17 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法

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US (1) US12460050B2 (enExample)
EP (1) EP3710514B1 (enExample)
JP (2) JP2021503029A (enExample)
CN (1) CN111491982B (enExample)
AU (1) AU2018369760B2 (enExample)
CA (1) CA3082130A1 (enExample)
WO (1) WO2019099525A1 (enExample)

Families Citing this family (13)

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US11186681B2 (en) 2016-10-07 2021-11-30 The University Of North Carolina At Chapel Hill S-Nitrosothiol-mediated hyperbranched polyesters
US11072668B2 (en) 2017-01-03 2021-07-27 The University Of North Carolina At Chapel Hill Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto
CN110461338A (zh) 2017-03-28 2019-11-15 北卡罗来纳大学查佩尔希尔分校 作为可生物降解抗菌支架的释放一氧化氮的聚氨基糖苷类和其制备方法
EP3710514B1 (en) 2017-11-15 2023-06-07 The University of North Carolina at Chapel Hill Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto
EP3762039A4 (en) 2018-03-06 2021-12-22 The University of North Carolina at Chapel Hill NITROGEN OXIDE RELEASING CYCLODEXTRIN AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDINGS AND RELATED PROCEDURES
EP3902841B1 (en) 2018-12-28 2025-01-29 The University of North Carolina at Chapel Hill Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto
JP7338113B2 (ja) * 2020-04-13 2023-09-05 大成建設株式会社 気体貯蔵放出化合物
EP4167954A4 (en) * 2020-06-18 2024-07-24 Nanometics LLC (D.B.A. Phd Biosciences) CHEMICALLY CROSS-LINKED ELASTOMERS FORMED BY MICHAEL ADDITION AND COMPOSITIONS COMPRISING SUCH ELASTOMERS
CN112023727B (zh) * 2020-08-14 2022-07-12 万华化学集团股份有限公司 一种抗污染抑菌反渗透膜、制备方法及其应用
CN114989265A (zh) * 2022-05-30 2022-09-02 浙江大学 一种具有高效广谱抗细菌、真菌功能的营养型支化结构聚多肽
CN115232318B (zh) * 2022-08-24 2023-12-26 宁波锋成先进能源材料研究院有限公司 一种非离子高分子表面活性剂及其制备方法和应用
CN118772400A (zh) * 2024-06-14 2024-10-15 华东理工大学 一种二醇二氮烯鎓超支化聚合物前驱体的制备方法
CN118955950B (zh) * 2024-07-30 2025-03-14 常熟威怡科技有限公司 一种纤维素抗菌水凝胶的制备方法和应用

Citations (2)

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CN106046382A (zh) * 2016-05-25 2016-10-26 暨南大学 一种装载一氧化氮的阳离子聚合物及其制备方法和应用
JP2020515688A (ja) * 2017-03-28 2020-05-28 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｃａｒｏｌｉｎａ Ａｔ Ｃｈａｐｅｌ Ｈｉｌｌ 生分解可能な抗菌性スキャフォールドとしての一酸化窒素放出性ポリアミノグリコシドおよびそれに関する方法背景

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