JP2021192835A5 - - Google Patents
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- JP2021192835A5 JP2021192835A5 JP2021150228A JP2021150228A JP2021192835A5 JP 2021192835 A5 JP2021192835 A5 JP 2021192835A5 JP 2021150228 A JP2021150228 A JP 2021150228A JP 2021150228 A JP2021150228 A JP 2021150228A JP 2021192835 A5 JP2021192835 A5 JP 2021192835A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025064456A JP2025106473A (ja) | 2018-08-23 | 2025-04-09 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862722100P | 2018-08-23 | 2018-08-23 | |
| US62/722,100 | 2018-08-23 | ||
| JP2020573539A JP6974671B2 (ja) | 2018-08-23 | 2019-08-22 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020573539A Division JP6974671B2 (ja) | 2018-08-23 | 2019-08-22 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025064456A Division JP2025106473A (ja) | 2018-08-23 | 2025-04-09 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021192835A JP2021192835A (ja) | 2021-12-23 |
| JP2021192835A5 true JP2021192835A5 (enExample) | 2022-08-30 |
| JP7667045B2 JP7667045B2 (ja) | 2025-04-22 |
| JP7667045B6 JP7667045B6 (ja) | 2025-06-05 |
Family
ID=68104708
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020573539A Active JP6974671B2 (ja) | 2018-08-23 | 2019-08-22 | 血液脳関門の透過性を向上させるための交流電界の使用 |
| JP2021007072A Active JP7233453B2 (ja) | 2018-08-23 | 2021-01-20 | 血液脳関門の透過性を向上させるための交流電界の使用 |
| JP2021150228A Active JP7667045B6 (ja) | 2018-08-23 | 2021-09-15 | 血液脳関門の透過性を向上させるための交流電界の使用 |
| JP2025064456A Pending JP2025106473A (ja) | 2018-08-23 | 2025-04-09 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020573539A Active JP6974671B2 (ja) | 2018-08-23 | 2019-08-22 | 血液脳関門の透過性を向上させるための交流電界の使用 |
| JP2021007072A Active JP7233453B2 (ja) | 2018-08-23 | 2021-01-20 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025064456A Pending JP2025106473A (ja) | 2018-08-23 | 2025-04-09 | 血液脳関門の透過性を向上させるための交流電界の使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US11400269B2 (enExample) |
| EP (6) | EP3892219B1 (enExample) |
| JP (4) | JP6974671B2 (enExample) |
| KR (3) | KR102651496B1 (enExample) |
| CN (6) | CN113908433B (enExample) |
| AU (2) | AU2019324585C1 (enExample) |
| BR (1) | BR112020025422A2 (enExample) |
| CA (2) | CA3100817C (enExample) |
| DK (4) | DK3773291T3 (enExample) |
| ES (4) | ES2911526T3 (enExample) |
| FI (1) | FI3878389T3 (enExample) |
| HU (3) | HUE059062T2 (enExample) |
| IL (2) | IL279466B2 (enExample) |
| MX (5) | MX2020013519A (enExample) |
| PL (3) | PL3804648T3 (enExample) |
| SG (1) | SG11202012592WA (enExample) |
| WO (1) | WO2020039390A1 (enExample) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| US20180001075A1 (en) | 2016-06-30 | 2018-01-04 | Novocure Limited | Arrays for Longitudinal Delivery of TTFields to a Body |
| WO2018134733A1 (en) | 2017-01-19 | 2018-07-26 | Moshe Giladi | System for viewing cell cultures under a microscope whilst applying ttfields |
| CN116159242A (zh) * | 2018-07-03 | 2023-05-26 | 埃德温·阊 | 使用交变电场提高细胞膜通透性 |
| KR102794415B1 (ko) | 2018-07-10 | 2025-04-09 | 노보큐어 게엠베하 | 교류 전기장을 사용한 바이러스 감염 억제 |
| EP3892219B1 (en) * | 2018-08-23 | 2022-06-01 | Novocure GmbH | Using alternating electric fields to increase permeability of the blood brain barrier |
| WO2020049482A1 (en) | 2018-09-07 | 2020-03-12 | Yaniv Alon | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| EP3840823B1 (en) | 2018-10-15 | 2023-07-12 | Novocure GmbH | Generating tumor treating fields (ttfields) with high uniformity throughout the brain |
| WO2020084596A1 (en) | 2018-10-25 | 2020-04-30 | Zeev Bomzon | Delivering alternating electric fields (e.g., ttfields) to a subject's spinal anatomy |
| EP3922301B1 (en) | 2018-11-19 | 2024-02-21 | Novocure GmbH | Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements |
| KR102606263B1 (ko) | 2018-11-29 | 2023-11-23 | 노보큐어 게엠베하 | 종양처리장을 전달하는 향상된 유연성 트랜스듀서 어레이 |
| EP3961565A1 (en) | 2019-01-08 | 2022-03-02 | Novocure GmbH | Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (ttfields) |
| KR102847999B1 (ko) | 2019-02-26 | 2025-08-21 | 노보큐어 게엠베하 | 표적 암세포들의 전기적 특징에 기초한 종양처리장 요법의 주파수 결정 |
| EP3954314B1 (en) | 2019-02-27 | 2025-01-08 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| EP3946322B1 (en) | 2019-03-29 | 2023-09-20 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
| US11291837B2 (en) | 2019-04-17 | 2022-04-05 | Novocure Gmbh | Uploading data from an isolated system without compromising isolation |
| JP7472264B2 (ja) | 2019-07-31 | 2024-04-22 | ノボキュア ゲーエムベーハー | 頭蓋骨インプラントに埋め込まれた電極による腫瘍治療電場（ｔｔフィールド）の印加 |
| EP4009971A1 (en) | 2019-08-05 | 2022-06-15 | Novocure GmbH | Increasing cancer cells' sensitivity to tumor treating fields (ttfields) by inhibiting il11 activity |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
| KR102873347B1 (ko) | 2019-09-10 | 2025-10-17 | 노보큐어 게엠베하 | 암 세포에 교번 전기장을 적용하고 체크포인트 억제제를 투여하여 암 세포의 활력성을 감소시키는 방법 |
| US12121739B2 (en) | 2019-12-31 | 2024-10-22 | Novocure Gmbh | Methods, systems, and apparatuses for managing temperatures induced by alternating fields |
| WO2021137085A2 (en) | 2019-12-31 | 2021-07-08 | Novocure Gmbh | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
| AU2020416669A1 (en) | 2019-12-31 | 2022-06-16 | Novocure Gmbh | Arrays for delivering tumor treating fields (TTFields) with individually accessible electrode elements and temperature sensors |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| BR112022021484A2 (pt) * | 2020-04-24 | 2022-12-13 | Novocure Gmbh | Uso de campos elétricos alternados para aumentar a permeabilidade da barreira hematoencefálica |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| US12114991B2 (en) | 2020-09-25 | 2024-10-15 | Novocure Gmbh | Varying the metallization area on individual electrode elements in a tumor treating fields (TTFields) system to maximize current without overheating |
| CA3202404A1 (en) | 2020-11-25 | 2022-06-02 | Novocure Gmbh | Increasing the efficacy of tumor treating fields (ttfields) by applying the ttfields at peak intensity less than half the time |
| WO2022130183A2 (en) * | 2020-12-17 | 2022-06-23 | Novocure Gmbh | Pyroelectric-based temperature sensing of transducer arrays for applying tumor treating fields (ttfields) |
| CN113008403B (zh) * | 2021-02-08 | 2022-08-12 | 清华大学 | 电场发生装置及测温电极装置 |
| EP4240470A1 (en) | 2021-02-17 | 2023-09-13 | Novocure Gmbh | Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas |
| US12440680B2 (en) | 2021-03-12 | 2025-10-14 | Novocure Gmbh | Methods of treating disease by skewing macrophage phenotype with alternating electric fields |
| EP4596025A1 (en) | 2021-03-31 | 2025-08-06 | Novocure Gmbh | Impedance tomography using electrodes of a tumor treating fields (ttfields) system |
| US20220323753A1 (en) * | 2021-04-08 | 2022-10-13 | Novocure Gmbh | Methods of Treating Neurodegenerative Disorders with Alternating Electric Fields |
| CN113509641A (zh) * | 2021-06-29 | 2021-10-19 | 北京康源嘉成生物科技有限公司 | 一种非药物且非侵入性开放血脑屏障的装置和方法 |
| WO2023275804A1 (en) | 2021-06-30 | 2023-01-05 | Novocure Gmbh | Using alternating electric fields at different frequencies to increase the permeability of the blood brain barrier and also to provide other benefits |
| CN114099963B (zh) * | 2021-12-22 | 2025-10-03 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统 |
| CN118043105A (zh) * | 2021-09-30 | 2024-05-14 | 诺沃库勒有限责任公司 | 在使用交变电场治疗受试者的同时降低电感 |
| US20230201616A1 (en) | 2021-12-29 | 2023-06-29 | Novocure Gmbh | Reducing Electrosensation Whilst Treating a Subject Using Alternating Electric Fields by Using Larger Cathodes and Smaller Anodes |
| CN118591405A (zh) | 2021-12-30 | 2024-09-03 | 诺沃库勒有限责任公司 | 使用肿瘤治疗电场(ttfields)选择治疗参数值 |
| CN114367060A (zh) * | 2022-01-13 | 2022-04-19 | 深圳大学 | 激光交变电场联合治疗仪 |
| MX2024010256A (es) | 2022-03-30 | 2024-08-28 | Novocure Gmbh | Reducción de la electrosensación durante el tratamiento de un sujeto mediante campos eléctricos alternos mediante el emparejamiento de matrices de transductores. |
| MX2024010258A (es) | 2022-03-30 | 2024-08-28 | Novocure Gmbh | Uso de periodos de enfriamiento intercalados para aumentar la intensidad pico de los campos de tratamiento de tumores. |
| WO2023242741A1 (en) | 2022-06-13 | 2023-12-21 | Novocure Gmbh | Systems and methods for increasing intestinal absorption of therapeutic agents |
| JP2025522725A (ja) | 2022-06-27 | 2025-07-17 | ノボキュア ゲーエムベーハー | 閉ループ技術を用いた、被験者を交流電場で治療すると同時の電気感覚の軽減 |
| EP4514445A1 (en) | 2022-06-30 | 2025-03-05 | Novocure GmbH | Electrode assembly for applying tumor treating fields (ttfields) that includes a plurality of thermally linked but electrically isolated graphite sheets |
| KR102637878B1 (ko) * | 2022-09-02 | 2024-02-19 | 주식회사 뉴로스피어 | 대뇌병변 산화철의 전자-펜톤효과를 이용한 전기장 대뇌자극치료기기 |
| JP2025532790A (ja) | 2022-09-30 | 2025-10-03 | ノボキュア ゲーエムベーハー | 電気感覚および／または皮膚刺激を軽減するための組成物、システム、および方法 |
| EP4561680A1 (en) | 2022-09-30 | 2025-06-04 | Novocure Gmbh | Reducing electrosensation while treating a subject using alternating electric fields by deactivating selected electrode elements |
| CN119998010A (zh) | 2022-09-30 | 2025-05-13 | 诺沃库勒有限责任公司 | 通过控制爬升特性在使用交变电场治疗受试者的同时降低电感应 |
| US20240108892A1 (en) | 2022-09-30 | 2024-04-04 | Novocure Gmbh | Changing the Orientation of Tumor Treating Fields (TTFields) by Adjusting the Amplitudes of Two or More Electric Fields that Are All In-Phase with Each Other |
| US20240207604A1 (en) | 2022-12-27 | 2024-06-27 | Novocure Gmbh | Multi Channel Device for Directional Shaping of Electric Fields e.g., Tumor Treating Fields (TTFields) |
| US20240216679A1 (en) | 2022-12-28 | 2024-07-04 | Novocure Gmbh | Positioning Electrode Elements on a Subject's Body to Provide Stronger Alternating Electric Fields (e.g.,TTFields) Without Overheating |
| WO2024141958A1 (en) | 2022-12-29 | 2024-07-04 | Novocure Gmbh | Reducing electrosensation while treating a subject using alternating electric fields by increasing the number of steps in a ramp-up portion of a waveform |
| WO2024141959A1 (en) | 2022-12-29 | 2024-07-04 | Novocure Gmbh | Reducing electrosensation during application of alternating electric fields by ensuring that successive increases in amplitude occur during opposite phases of an ac waveform |
| US12268863B2 (en) | 2023-02-06 | 2025-04-08 | Novocure Gmbh | Shiftable transducer array with anisotropic material layer |
| EP4661950A2 (en) | 2023-02-10 | 2025-12-17 | Novocure GmbH | Sequentially positioning sets of electrode arrays at nonoverlapping positions to ameliorate skin irritation during tumor treating fields (ttfields) therapy |
| WO2024201412A1 (en) | 2023-03-31 | 2024-10-03 | Novocure Gmbh | Microneedles to overcome contact resistance |
| CN120957783A (zh) | 2023-03-31 | 2025-11-14 | 诺沃库勒有限责任公司 | 通过逐渐增大旋转交变电场的幅度来降低在使用该电场治疗受试者时的电感觉 |
| WO2025068924A1 (en) | 2023-09-29 | 2025-04-03 | Novocure Gmbh | Using staggered changes in amplitude and frequency to ameliorate electrosensation during treatment with alternating electric fields |
| US20250108217A1 (en) | 2023-09-29 | 2025-04-03 | Novocure Gmbh | Applying an Electrical Signal Using a Multi-Part Electrode Assembly, and Interrupting the Electrical Signal if the Parts Begin to Separate |
| WO2025068984A1 (en) | 2023-09-29 | 2025-04-03 | Novocure Gmbh | Transducer arrays for tumor treating fields (ttfields) therapy that use a dedicated flex circuit to implement temperature sensing |
| CN119950998A (zh) * | 2023-12-26 | 2025-05-09 | 杭州海莱新创医疗科技有限公司 | 一种电极片类型识别方法及介质 |
| WO2025141502A1 (en) | 2023-12-29 | 2025-07-03 | Novocure Gmbh | Electrode assembly for delivering alternating electric fields with peripherally-positioned temperature sensors |
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