JP2021042225A5 - - Google Patents
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- JP2021042225A5 JP2021042225A5 JP2020192994A JP2020192994A JP2021042225A5 JP 2021042225 A5 JP2021042225 A5 JP 2021042225A5 JP 2020192994 A JP2020192994 A JP 2020192994A JP 2020192994 A JP2020192994 A JP 2020192994A JP 2021042225 A5 JP2021042225 A5 JP 2021042225A5
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 234
- 230000027455 binding Effects 0.000 claims 23
- 239000000427 antigen Substances 0.000 claims 21
- 102000036639 antigens Human genes 0.000 claims 21
- 108091007433 antigens Proteins 0.000 claims 21
- 238000004519 manufacturing process Methods 0.000 claims 19
- 150000001413 amino acids Chemical class 0.000 claims 12
- 108010073807 IgG Receptors Proteins 0.000 claims 8
- 102000009490 IgG Receptors Human genes 0.000 claims 8
- -1 neuroselpin Proteins 0.000 claims 7
- 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 claims 6
- 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 claims 6
- 125000000539 amino acid group Chemical group 0.000 claims 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 3
- 239000011575 calcium Substances 0.000 claims 3
- 229910001424 calcium ion Inorganic materials 0.000 claims 3
- 150000002500 ions Chemical class 0.000 claims 3
- 101000917826 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor II-a Proteins 0.000 claims 2
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 claims 2
- 102000019197 Superoxide Dismutase Human genes 0.000 claims 2
- 108010012715 Superoxide dismutase Proteins 0.000 claims 2
- 102100040347 TAR DNA-binding protein 43 Human genes 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102100022524 Alpha-1-antichymotrypsin Human genes 0.000 claims 1
- 102100032187 Androgen receptor Human genes 0.000 claims 1
- 102000004411 Antithrombin III Human genes 0.000 claims 1
- 108090000935 Antithrombin III Proteins 0.000 claims 1
- 102100035029 Ataxin-1 Human genes 0.000 claims 1
- 108010032963 Ataxin-1 Proteins 0.000 claims 1
- 102000007368 Ataxin-7 Human genes 0.000 claims 1
- 108010032953 Ataxin-7 Proteins 0.000 claims 1
- 102000007370 Ataxin2 Human genes 0.000 claims 1
- 108010032951 Ataxin2 Proteins 0.000 claims 1
- 108700040183 Complement C1 Inhibitor Proteins 0.000 claims 1
- 102000055157 Complement C1 Inhibitor Human genes 0.000 claims 1
- 102000012192 Cystatin C Human genes 0.000 claims 1
- 108010061642 Cystatin C Proteins 0.000 claims 1
- 101000923091 Danio rerio Aristaless-related homeobox protein Proteins 0.000 claims 1
- 201000008163 Dentatorubral pallidoluysian atrophy Diseases 0.000 claims 1
- 102100036912 Desmin Human genes 0.000 claims 1
- 108010044052 Desmin Proteins 0.000 claims 1
- 102100032248 Dysferlin Human genes 0.000 claims 1
- 108090000620 Dysferlin Proteins 0.000 claims 1
- 108010021472 Fc gamma receptor IIB Proteins 0.000 claims 1
- 102100039289 Glial fibrillary acidic protein Human genes 0.000 claims 1
- 101710193519 Glial fibrillary acidic protein Proteins 0.000 claims 1
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 102100031470 Homeobox protein ARX Human genes 0.000 claims 1
- 101000923090 Homo sapiens Homeobox protein ARX Proteins 0.000 claims 1
- 101000692768 Homo sapiens Paired mesoderm homeobox protein 2B Proteins 0.000 claims 1
- 101000891092 Homo sapiens TAR DNA-binding protein 43 Proteins 0.000 claims 1
- 102000036770 Islet Amyloid Polypeptide Human genes 0.000 claims 1
- 108010041872 Islet Amyloid Polypeptide Proteins 0.000 claims 1
- 102100040445 Keratin, type I cytoskeletal 14 Human genes 0.000 claims 1
- 102100025756 Keratin, type II cytoskeletal 5 Human genes 0.000 claims 1
- 108010066321 Keratin-14 Proteins 0.000 claims 1
- 108010070553 Keratin-5 Proteins 0.000 claims 1
- 102100029205 Low affinity immunoglobulin gamma Fc region receptor II-b Human genes 0.000 claims 1
- 102100026354 Paired mesoderm homeobox protein 2B Human genes 0.000 claims 1
- 101710150485 Polyadenylate-binding protein Proteins 0.000 claims 1
- 108091000054 Prion Proteins 0.000 claims 1
- 102000029797 Prion Human genes 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 101710150875 TAR DNA-binding protein 43 Proteins 0.000 claims 1
- 102000006467 TATA-Box Binding Protein Human genes 0.000 claims 1
- 108010044281 TATA-Box Binding Protein Proteins 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 108010091628 alpha 1-Antichymotrypsin Proteins 0.000 claims 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 claims 1
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 claims 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 claims 1
- 102000003802 alpha-Synuclein Human genes 0.000 claims 1
- 108090000185 alpha-Synuclein Proteins 0.000 claims 1
- 108010080146 androgen receptors Proteins 0.000 claims 1
- 229960005348 antithrombin iii Drugs 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 210000005045 desmin Anatomy 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 210000005046 glial fibrillary acidic protein Anatomy 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 claims 1
- 101150026046 iga gene Proteins 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 102000013498 tau Proteins Human genes 0.000 claims 1
- 108010026424 tau Proteins Proteins 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022120135A JP2022141941A (ja) | 2012-05-30 | 2022-07-28 | 会合化した抗原を消失させる抗原結合分子 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012123782 | 2012-05-30 | ||
| JP2012123782 | 2012-05-30 | ||
| JP2018087413A JP7016769B2 (ja) | 2012-05-30 | 2018-04-27 | 会合化した抗原を消失させる抗原結合分子 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018087413A Division JP7016769B2 (ja) | 2012-05-30 | 2018-04-27 | 会合化した抗原を消失させる抗原結合分子 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022120135A Division JP2022141941A (ja) | 2012-05-30 | 2022-07-28 | 会合化した抗原を消失させる抗原結合分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021042225A JP2021042225A (ja) | 2021-03-18 |
| JP2021042225A5 true JP2021042225A5 (enExample) | 2021-09-30 |
| JP7481236B2 JP7481236B2 (ja) | 2024-05-10 |
Family
ID=49673388
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014518714A Withdrawn JPWO2013180201A1 (ja) | 2012-05-30 | 2013-05-30 | 会合化した抗原を消失させる抗原結合分子 |
| JP2018087413A Active JP7016769B2 (ja) | 2012-05-30 | 2018-04-27 | 会合化した抗原を消失させる抗原結合分子 |
| JP2020192994A Active JP7481236B2 (ja) | 2012-05-30 | 2020-11-20 | 会合化した抗原を消失させる抗原結合分子 |
| JP2022120135A Pending JP2022141941A (ja) | 2012-05-30 | 2022-07-28 | 会合化した抗原を消失させる抗原結合分子 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014518714A Withdrawn JPWO2013180201A1 (ja) | 2012-05-30 | 2013-05-30 | 会合化した抗原を消失させる抗原結合分子 |
| JP2018087413A Active JP7016769B2 (ja) | 2012-05-30 | 2018-04-27 | 会合化した抗原を消失させる抗原結合分子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022120135A Pending JP2022141941A (ja) | 2012-05-30 | 2022-07-28 | 会合化した抗原を消失させる抗原結合分子 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20150353630A1 (enExample) |
| EP (2) | EP3892638A1 (enExample) |
| JP (4) | JPWO2013180201A1 (enExample) |
| DK (1) | DK2857419T3 (enExample) |
| ES (1) | ES2856272T3 (enExample) |
| WO (1) | WO2013180201A1 (enExample) |
Families Citing this family (97)
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| DK2006381T3 (en) | 2006-03-31 | 2016-02-22 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS |
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| US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| CA2806252C (en) | 2010-07-29 | 2019-05-14 | Xencor, Inc. | Antibodies with modified isoelectric points |
| MX365235B (es) | 2010-11-30 | 2019-05-28 | Chugai Pharmaceutical Co Ltd | Molécula de unión a antígeno capaz de unir repetidamente a la pluralidad de moléculas de antígeno. |
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| EP2762493B1 (en) | 2011-09-30 | 2021-06-09 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
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-
2013
- 2013-05-30 DK DK13796975.4T patent/DK2857419T3/da active
- 2013-05-30 EP EP21151149.8A patent/EP3892638A1/en active Pending
- 2013-05-30 JP JP2014518714A patent/JPWO2013180201A1/ja not_active Withdrawn
- 2013-05-30 ES ES13796975T patent/ES2856272T3/es active Active
- 2013-05-30 EP EP13796975.4A patent/EP2857419B1/en active Active
- 2013-05-30 WO PCT/JP2013/064979 patent/WO2013180201A1/ja not_active Ceased
- 2013-05-30 US US14/404,051 patent/US20150353630A1/en not_active Abandoned
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2018
- 2018-04-27 JP JP2018087413A patent/JP7016769B2/ja active Active
-
2020
- 2020-11-20 JP JP2020192994A patent/JP7481236B2/ja active Active
-
2021
- 2021-01-08 US US17/144,342 patent/US20210122812A1/en active Pending
-
2022
- 2022-07-28 JP JP2022120135A patent/JP2022141941A/ja active Pending
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