JP2020535804A5 - - Google Patents

Info

Publication number

JP2020535804A5

JP2020535804A5 JP2020516885A JP2020516885A JP2020535804A5 JP 2020535804 A5 JP2020535804 A5 JP 2020535804A5 JP 2020516885 A JP2020516885 A JP 2020516885A JP 2020516885 A JP2020516885 A JP 2020516885A JP 2020535804 A5 JP2020535804 A5 JP 2020535804A5

Authority

JP

Japan

Prior art keywords

nucleic acid

isolated nucleic

optionally

promoter

region

Prior art date

2018-09-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 150000007523 nucleic acids Chemical class 0.000 claims 31
• 108020004707 nucleic acids Proteins 0.000 claims 29
• 102000039446 nucleic acids Human genes 0.000 claims 29
• 108020004999 messenger RNA Proteins 0.000 claims 14
• 102000008221 Superoxide Dismutase-1 Human genes 0.000 claims 10
• 108010021188 Superoxide Dismutase-1 Proteins 0.000 claims 10
• 101710177611 DNA polymerase II large subunit Proteins 0.000 claims 4
• 101710184669 DNA polymerase II small subunit Proteins 0.000 claims 4
• 101000834253 Gallus gallus Actin, cytoplasmic 1 Proteins 0.000 claims 4
• 241000124008 Mammalia Species 0.000 claims 4
• 108091070501 miRNA Proteins 0.000 claims 4
• 239000002679 microRNA Substances 0.000 claims 4
• 108020005345 3' Untranslated Regions Proteins 0.000 claims 3
• 108020003589 5' Untranslated Regions Proteins 0.000 claims 3
• 108090000565 Capsid Proteins Proteins 0.000 claims 3
• 102100023321 Ceruloplasmin Human genes 0.000 claims 3
• 210000004027 cell Anatomy 0.000 claims 3
• 241000701022 Cytomegalovirus Species 0.000 claims 2
• 241000702421 Dependoparvovirus Species 0.000 claims 2
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
• 108091023045 Untranslated Region Proteins 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 239000003623 enhancer Substances 0.000 claims 2
• 239000002773 nucleotide Substances 0.000 claims 2
• 125000003729 nucleotide group Chemical group 0.000 claims 2
• 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 108091026890 Coding region Proteins 0.000 claims 1
• 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 1
• 108091026898 Leader sequence (mRNA) Proteins 0.000 claims 1
• 108091033773 MiR-155 Proteins 0.000 claims 1
• 102000009572 RNA Polymerase II Human genes 0.000 claims 1
• 108010009460 RNA Polymerase II Proteins 0.000 claims 1
• 102000014450 RNA Polymerase III Human genes 0.000 claims 1
• 108010078067 RNA Polymerase III Proteins 0.000 claims 1
• 108091036066 Three prime untranslated region Proteins 0.000 claims 1
• 230000002401 inhibitory effect Effects 0.000 claims 1
• 230000035772 mutation Effects 0.000 claims 1
• 210000002569 neuron Anatomy 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1