JP2020534840A5 - - Google Patents

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Publication number
JP2020534840A5
JP2020534840A5 JP2020517828A JP2020517828A JP2020534840A5 JP 2020534840 A5 JP2020534840 A5 JP 2020534840A5 JP 2020517828 A JP2020517828 A JP 2020517828A JP 2020517828 A JP2020517828 A JP 2020517828A JP 2020534840 A5 JP2020534840 A5 JP 2020534840A5
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JP
Japan
Prior art keywords
glp
derivative
conjugate
group
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020517828A
Other languages
English (en)
Japanese (ja)
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JP7751381B2 (ja
JP2020534840A (ja
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Application filed filed Critical
Priority claimed from PCT/KR2018/011586 external-priority patent/WO2019066586A1/ko
Publication of JP2020534840A publication Critical patent/JP2020534840A/ja
Priority to JP2023111438A priority Critical patent/JP2023138505A/ja
Publication of JP2020534840A5 publication Critical patent/JP2020534840A5/ja
Application granted granted Critical
Publication of JP7751381B2 publication Critical patent/JP7751381B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020517828A 2017-09-28 2018-09-28 Ｇｌｐ－２誘導体の持続型結合体 Active JP7751381B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023111438A JP2023138505A (ja) 2017-09-28 2023-07-06 Ｇｌｐ－２誘導体の持続型結合体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20170126577 2017-09-28
KR10-2017-0126577 2017-09-28
PCT/KR2018/011586 WO2019066586A1 (ko) 2017-09-28 2018-09-28 글루카곤 유사 펩타이드-2(glp-2) 유도체의 지속형 결합체

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023111438A Division JP2023138505A (ja) 2017-09-28 2023-07-06 Ｇｌｐ－２誘導体の持続型結合体

Publications (3)

Publication Number Publication Date
JP2020534840A JP2020534840A (ja) 2020-12-03
JP2020534840A5 true JP2020534840A5 (enExample) 2023-07-24
JP7751381B2 JP7751381B2 (ja) 2025-10-08

Family

ID=65902619

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020517828A Active JP7751381B2 (ja) 2017-09-28 2018-09-28 Ｇｌｐ－２誘導体の持続型結合体
JP2023111438A Pending JP2023138505A (ja) 2017-09-28 2023-07-06 Ｇｌｐ－２誘導体の持続型結合体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023111438A Pending JP2023138505A (ja) 2017-09-28 2023-07-06 Ｇｌｐ－２誘導体の持続型結合体

Country Status (18)

Country Link
US (3) US11530249B2 (enExample)
EP (1) EP3689898B1 (enExample)
JP (2) JP7751381B2 (enExample)
KR (2) KR102681143B1 (enExample)
CN (1) CN111433221B (enExample)
AR (1) AR113258A1 (enExample)
AU (1) AU2018339210B2 (enExample)
BR (1) BR112020006189A2 (enExample)
CA (1) CA3084326A1 (enExample)
EA (1) EA202090571A1 (enExample)
IL (1) IL273528B2 (enExample)
MX (1) MX2020004453A (enExample)
PH (1) PH12020550105A1 (enExample)
SA (1) SA520411644B1 (enExample)
SG (1) SG11202002563WA (enExample)
TW (2) TWI795443B (enExample)
WO (1) WO2019066586A1 (enExample)
ZA (1) ZA202001888B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202111311WA (en) 2019-06-14 2021-12-30 Zealand Pharma As Pharmaceutical parenteral composition of dual glp1/2 agonist
JP7846622B2 (ja) * 2019-12-24 2026-04-15 ハンミ ファーマシューティカル カンパニー リミテッド Ｇｌｐ－２又はその結合体を含む、代謝性骨疾患の予防又は治療用薬学的組成物
EP4126004A1 (en) 2020-03-30 2023-02-08 Zealand Pharma A/S Agonist combination
WO2021201654A1 (ko) 2020-04-03 2021-10-07 한미약품 주식회사 Glp-2 유도체 또는 이의 지속형 결합체를 포함하는 방사선요법, 화학요법, 또는 이들의 조합으로 유발된 점막염의 예방 또는 치료용 약학적 조성물
MX2022014671A (es) * 2020-05-22 2023-02-13 Hanmi Pharm Ind Co Ltd Formulacion liquida de conjugado de glp-2 de accion prolongada.
BR112022025141A2 (pt) 2020-06-09 2023-04-25 Vectivbio Ag Fabricação, formulação e dosagem de apraglutida
KR20220092446A (ko) * 2020-12-24 2022-07-01 한미약품 주식회사 단장증후군의 예방 또는 치료를 위한 인슐린 분비 펩타이드 및 glp-2의 병용 요법
JP2025513345A (ja) * 2022-04-18 2025-04-24 ハンミ ファーマシューティカル カンパニー リミテッド 腸疾患の予防又は治療のためのＧＬＰ－２と、インスリン分泌ペプチド、ＴＮＦα抑制剤、又はその両方の併用療法
CN120435309A (zh) 2022-12-23 2025-08-05 韩美药品株式会社 含有glp-2衍生物或其长效缀合物的用于预防或治疗移植物抗宿主病的药物组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096871A (en) 1995-04-14 2000-08-01 Genentech, Inc. Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
DK1360202T3 (da) * 2001-02-16 2008-09-22 Conjuchem Biotechnologies Inc Langvarigt glucagon-lignende peptid 2 (GLP-2) til behandling af gastrointestinale sygdomme og lidelser
US20090238838A1 (en) * 2003-11-13 2009-09-24 Hanmi Pharm. Ind. Co. Ltd. Insulinotropic peptide conjugate using an immunoglobulin fc
HRP20060362A2 (en) * 2004-04-23 2007-03-31 Conjuchem Biotechnologies Inc. Method for the purification of albumin conjugates
UA95235C2 (en) * 2005-05-04 2011-07-25 Зииланд Фарма А/С Glucagon-like-peptide-2 (glp-2) analogues
JP2008169195A (ja) * 2007-01-05 2008-07-24 Hanmi Pharmaceutical Co Ltd キャリア物質を用いたインスリン分泌ペプチド薬物結合体
US20110171164A1 (en) * 2008-09-19 2011-07-14 Nektar Therapeutics Polymer conjugates of glp-2-like peptides
KR101746686B1 (ko) * 2010-10-26 2017-06-15 한미사이언스 주식회사 면역글로불린 단편을 이용한 글루카곤 유사 펩타이드―２（ｇｌｐ―２）약물 결합체
JP6206972B2 (ja) * 2011-09-12 2017-10-04 アムニクス オペレーティング インコーポレイテッド グルカゴン様ペプチド−２組成物およびその作製法および使用法
KR101895047B1 (ko) * 2011-12-30 2018-09-06 한미사이언스 주식회사 면역글로불린 단편을 이용한 위치 특이적 글루카곤 유사 펩타이드-2 약물 결합체

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