JP2020534273A5 - - Google Patents
Info
- Publication number
- JP2020534273A5 JP2020534273A5 JP2020515025A JP2020515025A JP2020534273A5 JP 2020534273 A5 JP2020534273 A5 JP 2020534273A5 JP 2020515025 A JP2020515025 A JP 2020515025A JP 2020515025 A JP2020515025 A JP 2020515025A JP 2020534273 A5 JP2020534273 A5 JP 2020534273A5
- Authority
- JP
- Japan
- Prior art keywords
- fibrosis
- seq
- amino acid
- acid sequence
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2017-0118917 | 2017-09-15 | ||
| KR20170118917 | 2017-09-15 | ||
| PCT/KR2018/010903 WO2019054819A1 (ko) | 2017-09-15 | 2018-09-17 | 라이실 tRNA 합성효소 N-말단에 특이적으로 결합하는 항체를 유효성분으로 포함하는 면역세포 이동 관련 질환의 예방 또는 치료용 약학적 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020534273A JP2020534273A (ja) | 2020-11-26 |
| JP2020534273A5 true JP2020534273A5 (https=) | 2022-05-30 |
| JP7511241B2 JP7511241B2 (ja) | 2024-07-05 |
Family
ID=65723723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515025A Active JP7511241B2 (ja) | 2017-09-15 | 2018-09-17 | リシル－ｔＲＮＡ合成酵素Ｎ末端に特異的に結合する抗体を有効成分として含む免疫細胞の遊走関連疾患の予防又は治療用薬学的組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11965038B2 (https=) |
| EP (1) | EP3682898A4 (https=) |
| JP (1) | JP7511241B2 (https=) |
| KR (1) | KR102163465B1 (https=) |
| CN (1) | CN111629752B (https=) |
| AU (1) | AU2018332491B2 (https=) |
| BR (1) | BR112020004935A8 (https=) |
| CA (1) | CA3084461C (https=) |
| RU (1) | RU2749591C1 (https=) |
| WO (1) | WO2019054819A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019020166A2 (pt) | 2017-03-27 | 2020-06-30 | Medicinal Bioconvergence Research Center | anticorpo que se liga especificamente a região n-terminal de lisil-trna sintetase exposta na membrana celular |
| CA3084461C (en) | 2017-09-15 | 2025-06-17 | Zymedi Co., Ltd. | PHARMACEUTICAL COMPOSITION COMPRISING AN ANTIBODY THAT BINDS SPECIFICALLY TO THE N-TERMINAL END OF LYSYL TRANSFER RIBONUCLE ACID (NTRNA) SYNTHETASE AS AN ACTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF A DISEASE RELATED TO IMMUNE CELL MIGRATION |
| WO2020060156A1 (ko) * | 2018-09-17 | 2020-03-26 | 재단법인 의약바이오컨버젼스연구단 | 세포 외막에 노출되는 라이실-tRNA 합성효소 N-말단 영역에 특이적으로 결합하는 항체 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9928136D0 (en) * | 1999-11-29 | 2000-01-26 | Rose Marlene L | Organ rejection and associated conditions |
| KR100961392B1 (ko) | 2008-04-15 | 2010-06-07 | 이화여자대학교 산학협력단 | 항체 파지 표면제시 라이브러리 제조방법, 상기 방법에의해 제조된 항체 파지 표면제시 라이브러리, 상기 항체파지 표면제시 라이브러리 유전자를 포함한 파지미드 벡터 |
| RU2465330C1 (ru) * | 2008-08-18 | 2012-10-27 | Сеул Нэшнл Юниверсити Индастри Фаундейшн | СПОСОБ ИНГИБИРОВАНИЯ МЕТАСТАЗИРОВАНИЯ ЗЛОКАЧЕСТВЕННОЙ ОПУХОЛИ ИЛИ МИГРАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ПОСРЕДСТВОМ СНИЖЕНИЯ КЛЕТОЧНОГО УРОВНЯ ЛИЗИЛ-тРНК-СИНТЕТАЗЫ (ВАРИАНТЫ), КОМПОЗИЦИЯ И ПРИМЕНЕНИЕ ВЕКТОРА ЭКСПРЕССИИ ИЛИ АНТИТЕЛА ПРОТИВ KRS ДЛЯ ИНГИБИРОВАНИЯ МЕТАСТАЗИРОВАНИЯ ЗЛОКАЧЕСТВЕННОЙ ОПУХОЛИ ИЛИ МИГРАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК |
| AU2008360729A1 (en) | 2008-08-18 | 2010-02-25 | Seoul National University Industry Foundation | Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl tRNA synthetase |
| KR101009501B1 (ko) * | 2008-10-10 | 2011-01-18 | 서울대학교산학협력단 | 항-라이실 티알엔에이 합성효소 항체 및 항-라미닌 수용체 항체를 유효성분으로 포함하는 암 진단용 조성물 |
| US9127268B2 (en) * | 2009-12-11 | 2015-09-08 | Atyr Pharma, Inc. | Aminoacyl tRNA synthetases for modulating inflammation |
| CA2800281C (en) * | 2010-06-01 | 2021-01-12 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases |
| JP2017502672A (ja) | 2013-12-30 | 2017-01-26 | メディシナル バイオコンバージェンス リサーチ センター | 抗ｋｒｓモノクロナル抗体及びこれの用途 |
| US11111396B2 (en) | 2014-10-17 | 2021-09-07 | C3 Nano, Inc. | Transparent films with control of light hue using nanoscale colorants |
| US10050713B2 (en) | 2015-03-02 | 2018-08-14 | Futurewei Technologies, Inc. | Optical transceiver using duplex media, self-homodyne detection (SHD), coherent detection, and uncooled laser |
| KR20180069146A (ko) | 2016-12-14 | 2018-06-25 | 만도헬라일렉트로닉스(주) | 주차 조향 보조 시스템 및 그 제어방법 |
| BR112019020166A2 (pt) | 2017-03-27 | 2020-06-30 | Medicinal Bioconvergence Research Center | anticorpo que se liga especificamente a região n-terminal de lisil-trna sintetase exposta na membrana celular |
| CA3084461C (en) * | 2017-09-15 | 2025-06-17 | Zymedi Co., Ltd. | PHARMACEUTICAL COMPOSITION COMPRISING AN ANTIBODY THAT BINDS SPECIFICALLY TO THE N-TERMINAL END OF LYSYL TRANSFER RIBONUCLE ACID (NTRNA) SYNTHETASE AS AN ACTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF A DISEASE RELATED TO IMMUNE CELL MIGRATION |
-
2018
- 2018-09-17 CA CA3084461A patent/CA3084461C/en active Active
- 2018-09-17 KR KR1020180111060A patent/KR102163465B1/ko active Active
- 2018-09-17 JP JP2020515025A patent/JP7511241B2/ja active Active
- 2018-09-17 AU AU2018332491A patent/AU2018332491B2/en active Active
- 2018-09-17 US US16/646,240 patent/US11965038B2/en active Active
- 2018-09-17 WO PCT/KR2018/010903 patent/WO2019054819A1/ko not_active Ceased
- 2018-09-17 CN CN201880074372.5A patent/CN111629752B/zh active Active
- 2018-09-17 BR BR112020004935A patent/BR112020004935A8/pt unknown
- 2018-09-17 EP EP18856914.9A patent/EP3682898A4/en active Pending
- 2018-09-17 RU RU2020113539A patent/RU2749591C1/ru active
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