JP2020524993A5 - - Google Patents
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- Publication number
- JP2020524993A5 JP2020524993A5 JP2019568601A JP2019568601A JP2020524993A5 JP 2020524993 A5 JP2020524993 A5 JP 2020524993A5 JP 2019568601 A JP2019568601 A JP 2019568601A JP 2019568601 A JP2019568601 A JP 2019568601A JP 2020524993 A5 JP2020524993 A5 JP 2020524993A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic
- cron
- existent
- nucleic acid
- orf1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022187239A JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762518898P | 2017-06-13 | 2017-06-13 | |
| US62/518,898 | 2017-06-13 | ||
| US201762597387P | 2017-12-11 | 2017-12-11 | |
| US62/597,387 | 2017-12-11 | ||
| US201862676730P | 2018-05-25 | 2018-05-25 | |
| US62/676,730 | 2018-05-25 | ||
| PCT/US2018/037379 WO2018232017A1 (en) | 2017-06-13 | 2018-06-13 | Compositions comprising curons and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022187239A Division JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020524993A JP2020524993A (ja) | 2020-08-27 |
| JP2020524993A5 true JP2020524993A5 (enExample) | 2021-07-26 |
Family
ID=62846247
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019568601A Withdrawn JP2020524993A (ja) | 2017-06-13 | 2018-06-13 | クロンを含む組成物及びその使用 |
| JP2022187239A Withdrawn JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A Pending JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022187239A Withdrawn JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A Pending JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20200123203A1 (enExample) |
| EP (1) | EP3638797A1 (enExample) |
| JP (3) | JP2020524993A (enExample) |
| KR (2) | KR20200038236A (enExample) |
| CN (1) | CN111108208A (enExample) |
| AU (2) | AU2018285860A1 (enExample) |
| BR (1) | BR112019026226A2 (enExample) |
| CA (1) | CA3066750A1 (enExample) |
| IL (1) | IL271275B1 (enExample) |
| MX (2) | MX2019015018A (enExample) |
| WO (1) | WO2018232017A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120795059A (zh) | 2018-08-27 | 2025-10-17 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| US11166996B2 (en) | 2018-12-12 | 2021-11-09 | Flagship Pioneering Innovations V, Inc. | Anellovirus compositions and methods of use |
| EP3894568A2 (en) * | 2018-12-12 | 2021-10-20 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering secreted therapeutic modalities |
| MX2021006977A (es) * | 2018-12-12 | 2021-10-13 | Flagship Pioneering Innovations V Inc | Anellosomas y metodos de uso. |
| WO2020123753A2 (en) * | 2018-12-12 | 2020-06-18 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering intracellular therapeutic modalities |
| EP3894569A2 (en) * | 2018-12-12 | 2021-10-20 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering protein replacement therapeutic modalities |
| CN114258398A (zh) | 2019-06-13 | 2022-03-29 | 总医院公司 | 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法 |
| CA3147875A1 (en) | 2019-07-19 | 2021-01-28 | Flagship Pioneering Innovations Vi, Llc | Recombinase compositions and methods of use |
| TW202239762A (zh) * | 2020-06-12 | 2022-10-16 | 美商旗艦先鋒創新公司 | 桿狀病毒表現系統 |
| KR20230036110A (ko) * | 2020-06-12 | 2023-03-14 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 탠덤 아넬로바이러스 구축물 |
| TW202221126A (zh) * | 2020-06-17 | 2022-06-01 | 美商旗艦先鋒創新公司 | 用於鑑別及特徵化指環病毒之方法及其用途 |
| CN116670154A (zh) | 2020-07-24 | 2023-08-29 | 总医院公司 | 增强的病毒样颗粒及使用其递送至细胞的方法 |
| US12018254B2 (en) * | 2020-07-27 | 2024-06-25 | Wisconsin Alumni Research Foundation | Methods of making unbiased phage libraries |
| KR20230124682A (ko) * | 2020-12-23 | 2023-08-25 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | Rna를 봉입하는 아넬로바이러스 캡시드의 시험관 내어셈블리 |
| KR20230146560A (ko) * | 2021-02-08 | 2023-10-19 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 하이브리드 aav-아넬로벡터 |
| EP4419677A4 (en) * | 2021-10-18 | 2025-09-24 | Flagship Pioneering Innovations Vii Llc | DNA COMPOSITIONS AND RELATED METHODS |
| WO2024129988A1 (en) | 2022-12-14 | 2024-06-20 | Flagship Pioneering Innovations Vii, Llc | Compositions and methods for delivery of therapeutic agents to bone |
| WO2025194138A1 (en) | 2024-03-14 | 2025-09-18 | Tessera Therapeutics, Inc. | St1cas9 compositions and methods for modulating a genome |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR751473A (fr) * | 1932-06-01 | 1933-09-04 | Poste d'incendie | |
| JP2001500015A (ja) | 1996-09-06 | 2001-01-09 | トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | T7ポリメラーゼを利用する組換えアデノ随伴ウイルスの誘導可能な製造方法 |
| US6693086B1 (en) | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
| US6395472B1 (en) * | 1999-02-05 | 2002-05-28 | Abbott Laboratories | Methods of utilizing the TT virus |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| SG190613A1 (en) | 2003-07-16 | 2013-06-28 | Protiva Biotherapeutics Inc | Lipid encapsulated interfering rna |
| CN1882693B (zh) | 2003-09-15 | 2012-08-15 | 普洛体维生物治疗公司 | 聚乙二醇修饰的脂质化合物及其应用 |
| US8084599B2 (en) | 2004-03-15 | 2011-12-27 | City Of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA |
| WO2005120152A2 (en) | 2004-06-07 | 2005-12-22 | Protiva Biotherapeutics, Inc. | Cationic lipids and methods of use |
| ATE536418T1 (de) | 2004-06-07 | 2011-12-15 | Protiva Biotherapeutics Inc | Lipidverkapselte interferenz-rna |
| AU2005326322B2 (en) | 2004-07-01 | 2009-02-05 | Yale University | Targeted and high density drug loaded polymeric materials |
| WO2007048046A2 (en) | 2005-10-20 | 2007-04-26 | Protiva Biotherapeutics, Inc. | Sirna silencing of filovirus gene expression |
| WO2007051303A1 (en) | 2005-11-02 | 2007-05-10 | Protiva Biotherapeutics, Inc. | MODIFIED siRNA MOLECULES AND USES THEREOF |
| US7915399B2 (en) | 2006-06-09 | 2011-03-29 | Protiva Biotherapeutics, Inc. | Modified siRNA molecules and uses thereof |
| NZ588583A (en) | 2008-04-15 | 2012-08-31 | Protiva Biotherapeutics Inc | Novel lipid formulations for nucleic acid delivery |
| EP2379083B1 (en) | 2008-12-18 | 2017-08-16 | Dicerna Pharmaceuticals, Inc. | Extended dicer substrate agents and methods for the specific inhibition of gene expression |
| WO2010093788A2 (en) | 2009-02-11 | 2010-08-19 | Dicerna Pharmaceuticals, Inc. | Multiplex dicer substrate rna interference molecules having joining sequences |
| WO2010099510A2 (en) | 2009-02-27 | 2010-09-02 | The Administrators Of The Tulane Educational Fund | Amino acid-based compounds, their methods of use, and methods of screening |
| US8236943B2 (en) | 2009-07-01 | 2012-08-07 | Protiva Biotherapeutics, Inc. | Compositions and methods for silencing apolipoprotein B |
| US8283333B2 (en) | 2009-07-01 | 2012-10-09 | Protiva Biotherapeutics, Inc. | Lipid formulations for nucleic acid delivery |
| US9676828B2 (en) * | 2010-06-23 | 2017-06-13 | Deutsches Krebsforschungszentrum | Rearranged TT virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity |
| US9409987B2 (en) * | 2011-04-15 | 2016-08-09 | Compugen Ltd | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer |
| LT3401400T (lt) | 2012-05-25 | 2019-06-10 | The Regents Of The University Of California | Būdai ir kompozicijos, skirtos rnr molekulės nukreipiamai tikslinės dnr modifikacijai ir rnr molekulės nukreipiamam transkripcijos moduliavimui |
| PL4397760T3 (pl) | 2012-10-23 | 2026-03-30 | Toolgen Incorporated | Kompozycja do rozszczepiania docelowego dna zawierająca prowadzące rna specyficzne dla docelowego dna i kwas nukleinowy kodujący białko cas lub białko cas oraz jej zastosowanie |
| ES2576126T3 (es) | 2012-12-12 | 2016-07-05 | The Broad Institute, Inc. | Modificación por tecnología genética y optimización de sistemas, métodos y composiciones enzimáticas mejorados para la manipulación de secuencias |
| EP2931898B1 (en) | 2012-12-12 | 2016-03-09 | The Broad Institute, Inc. | Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| CN114634950A (zh) | 2012-12-12 | 2022-06-17 | 布罗德研究所有限公司 | 用于序列操纵的crispr-cas组分系统、方法以及组合物 |
| US20140310830A1 (en) | 2012-12-12 | 2014-10-16 | Feng Zhang | CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes |
| JP2016504026A (ja) | 2012-12-12 | 2016-02-12 | ザ・ブロード・インスティテュート・インコーポレイテッド | 配列操作のための系、方法および最適化ガイド組成物のエンジニアリング |
| BR112016013213A2 (pt) * | 2013-12-12 | 2017-12-05 | Massachusetts Inst Technology | administração, uso e aplicações terapêuticas dos sistemas crispr-cas e composições para visar distúrbios e doenças usando componentes de administração de partículas |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
-
2018
- 2018-06-12 IL IL271275A patent/IL271275B1/en unknown
- 2018-06-13 MX MX2019015018A patent/MX2019015018A/es unknown
- 2018-06-13 JP JP2019568601A patent/JP2020524993A/ja not_active Withdrawn
- 2018-06-13 CN CN201880051296.6A patent/CN111108208A/zh active Pending
- 2018-06-13 EP EP18738411.0A patent/EP3638797A1/en active Pending
- 2018-06-13 CA CA3066750A patent/CA3066750A1/en active Pending
- 2018-06-13 AU AU2018285860A patent/AU2018285860A1/en not_active Abandoned
- 2018-06-13 WO PCT/US2018/037379 patent/WO2018232017A1/en not_active Ceased
- 2018-06-13 BR BR112019026226-1A patent/BR112019026226A2/pt unknown
- 2018-06-13 KR KR1020207000972A patent/KR20200038236A/ko not_active Ceased
- 2018-06-13 US US16/622,146 patent/US20200123203A1/en not_active Abandoned
- 2018-06-13 KR KR1020257004957A patent/KR20250028508A/ko active Pending
-
2019
- 2019-03-27 US US16/366,571 patent/US20190211361A1/en not_active Abandoned
- 2019-12-11 MX MX2023011657A patent/MX2023011657A/es unknown
-
2020
- 2020-01-16 US US16/744,363 patent/US20200385757A1/en not_active Abandoned
-
2022
- 2022-07-15 US US17/812,896 patent/US20230279423A1/en not_active Abandoned
- 2022-11-24 JP JP2022187239A patent/JP2023010961A/ja not_active Withdrawn
-
2024
- 2024-04-23 JP JP2024069618A patent/JP2024087003A/ja active Pending
-
2025
- 2025-01-24 AU AU2025200497A patent/AU2025200497A1/en active Pending
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