JP2020521958A5 - - Google Patents
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- Publication number
- JP2020521958A5 JP2020521958A5 JP2019564473A JP2019564473A JP2020521958A5 JP 2020521958 A5 JP2020521958 A5 JP 2020521958A5 JP 2019564473 A JP2019564473 A JP 2019564473A JP 2019564473 A JP2019564473 A JP 2019564473A JP 2020521958 A5 JP2020521958 A5 JP 2020521958A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- aliquot
- analyzer
- processed
- mass spectrometer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 238000000034 method Methods 0.000 claims description 98
- 238000004458 analytical method Methods 0.000 claims description 74
- 239000012491 analyte Substances 0.000 claims description 53
- 239000003153 chemical reaction reagent Substances 0.000 claims description 37
- 238000006243 chemical reaction Methods 0.000 claims description 27
- 238000001514 detection method Methods 0.000 claims description 13
- 238000004949 mass spectrometry Methods 0.000 claims description 10
- 238000010828 elution Methods 0.000 claims description 9
- 230000003287 optical effect Effects 0.000 claims description 9
- 238000005070 sampling Methods 0.000 claims description 8
- 238000003018 immunoassay Methods 0.000 claims description 6
- 238000000926 separation method Methods 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 3
- 239000007924 injection Substances 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000000523 sample Substances 0.000 claims 122
- 150000002500 ions Chemical class 0.000 claims 12
- 238000002360 preparation method Methods 0.000 claims 10
- 239000002904 solvent Substances 0.000 claims 4
- 239000007850 fluorescent dye Substances 0.000 claims 3
- 238000005086 pumping Methods 0.000 claims 3
- 239000007853 buffer solution Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000012141 concentrate Substances 0.000 claims 2
- 239000012488 sample solution Substances 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 239000012925 reference material Substances 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
- 238000007885 magnetic separation Methods 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 4
- 239000000090 biomarker Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000006920 protein precipitation Effects 0.000 description 2
- 239000013060 biological fluid Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000000984 immunochemical effect Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023037413A JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762509601P | 2017-05-22 | 2017-05-22 | |
| US62/509,601 | 2017-05-22 | ||
| US201762607773P | 2017-12-19 | 2017-12-19 | |
| US62/607,773 | 2017-12-19 | ||
| PCT/US2018/033927 WO2018217778A1 (en) | 2017-05-22 | 2018-05-22 | Integrated sample processing system with multiple detection capability |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023037413A Division JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521958A JP2020521958A (ja) | 2020-07-27 |
| JP2020521958A5 true JP2020521958A5 (enExample) | 2021-07-26 |
Family
ID=62621016
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019564473A Withdrawn JP2020521958A (ja) | 2017-05-22 | 2018-05-22 | 複数の検出能力を有する統合試料処理システム |
| JP2023037413A Active JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A Pending JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023037413A Active JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A Pending JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11402386B2 (enExample) |
| EP (2) | EP4411387A3 (enExample) |
| JP (3) | JP2020521958A (enExample) |
| CN (2) | CN116825604A (enExample) |
| WO (1) | WO2018217778A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4411387A3 (en) | 2017-05-22 | 2024-11-13 | Beckman Coulter, Inc. | Integrated sample processing system with multiple detection capability |
| US11125738B2 (en) | 2018-11-06 | 2021-09-21 | Thermo Finnigan Llc | Blood sample analysis systems and methods |
| WO2020129032A1 (en) * | 2018-12-21 | 2020-06-25 | Dh Technologies Development Pte. Ltd. | Method for measuring testosterone using lc-msms |
| WO2020225971A1 (ja) | 2019-05-08 | 2020-11-12 | 株式会社日立ハイテク | 自動分析装置の前処理方法 |
| JP7671510B2 (ja) | 2019-09-25 | 2025-05-02 | ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー | パルス・モード電荷検出質量分析のための装置および方法 |
| EP4038361B1 (en) | 2019-09-30 | 2024-06-19 | DH Technologies Development Pte. Ltd. | Sampling probe with internal sampling for use in mass spectrometry systems and methods |
| WO2021072186A1 (en) | 2019-10-10 | 2021-04-15 | The Trustees Of Indiana University | System and method for identifying, selecting and purifying particles |
| CN113777332B (zh) * | 2020-06-09 | 2024-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 免疫分析仪和自身免疫分析方法 |
| CN116670513A (zh) * | 2020-12-30 | 2023-08-29 | 贝克曼库尔特有限公司 | 利用单个校准品的临床实验室自动化系统 |
| CN117581104A (zh) * | 2021-06-03 | 2024-02-20 | Dh科技发展私人贸易有限公司 | 用于利用结合磁珠的质谱法进行样品处理的系统和方法 |
| CN114047345B (zh) * | 2021-11-09 | 2022-09-09 | 中元汇吉生物技术股份有限公司 | 一种样本优先调度方法、调度系统及检测系统 |
| CN118235036A (zh) | 2021-11-12 | 2024-06-21 | 贝克曼库尔特有限公司 | 用于表面增强拉曼光谱的系统和方法 |
| CN116413253B (zh) * | 2023-03-15 | 2025-10-10 | 宁波海尔施智造有限公司 | 一种人乳头瘤病毒检测试剂及其应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58628B2 (ja) * | 1976-08-17 | 1983-01-07 | 株式会社島津製作所 | 自動分折装置 |
| US20030027216A1 (en) | 2001-07-02 | 2003-02-06 | Kiernan Urban A. | Analysis of proteins from biological fluids using mass spectrometric immunoassay |
| US6746648B1 (en) | 2000-06-15 | 2004-06-08 | Beckman Coulter, Inc. | Method and system for transporting and storing multiple reagent packs and reagent packs used therein |
| US6843481B1 (en) | 2000-10-10 | 2005-01-18 | Beckman Coulter, Inc. | Fluid-moving device with a clearance seal |
| US6520755B1 (en) | 2000-10-10 | 2003-02-18 | Beckman Coulter, Inc. | Fluid-moving device with integrated valve |
| US7128874B2 (en) | 2001-01-26 | 2006-10-31 | Beckman Coulter, Inc. | Method and system for picking and placing vessels |
| US6790412B2 (en) | 2001-02-06 | 2004-09-14 | Beckman Coulter, Inc. | Bulk vessel feeder |
| US7217391B2 (en) | 2001-03-16 | 2007-05-15 | Beckman Coulter, Inc. | Rotary incubation station for immunoassay systems |
| US6790413B2 (en) | 2001-05-03 | 2004-09-14 | Beckman Coulter, Inc. | Sample presentation unit |
| US7632686B2 (en) | 2002-10-03 | 2009-12-15 | Anderson Forschung Group | High sensitivity quantitation of peptides by mass spectrometry |
| US20060159587A1 (en) * | 2005-01-19 | 2006-07-20 | Beckman Coulter, Inc. | Automated clinical analyzer with dual level storage and access |
| JP2007000687A (ja) | 2005-06-21 | 2007-01-11 | Shimadzu Corp | 生体試料中のペプチド分析方法及び装置 |
| WO2008005455A2 (en) | 2006-07-03 | 2008-01-10 | The Johns Hopkins University | Peptide antibody depletion and its application to mass spectrometry sample preparation |
| JP2010175355A (ja) | 2009-01-29 | 2010-08-12 | Hitachi High-Technologies Corp | 自動分析装置 |
| WO2010092958A1 (ja) | 2009-02-10 | 2010-08-19 | 株式会社日立ハイテクノロジーズ | 質量分析技術を用いた免疫分析方法および免疫分析システム |
| CN104722342B (zh) * | 2009-03-24 | 2017-01-11 | 芝加哥大学 | 滑动式芯片装置和方法 |
| WO2011012657A1 (en) * | 2009-07-29 | 2011-02-03 | F. Hoffmann-La Roche Ag | Automatic analyzer |
| HUE055674T2 (hu) * | 2010-10-29 | 2021-12-28 | Thermo Fisher Scientific Oy | Rendszerelrendezés automatizált mintaelõkészítõ és -elemzõ rendszerhez |
| EP2466308B1 (en) | 2010-12-14 | 2018-02-07 | Universitätsmedizin Greifswald Körperschaft des Öffentlichen Rechts Institut für Immunologie und Transfusionsmedizin Abteilung Immunologie | Immunoassay device and use of the device (immunoassay) |
| WO2012170549A1 (en) | 2011-06-06 | 2012-12-13 | Waters Technologies Corporation | Compositions, methods, and kits for quantifying target analytes in a sample |
| US9328386B2 (en) * | 2011-08-16 | 2016-05-03 | Evotec (München) Gmbh | Markers for susceptibility to an inhibitor of an Src-family kinase |
| US9074236B2 (en) * | 2012-05-01 | 2015-07-07 | Oxoid Limited | Apparatus and methods for microbial identification by mass spectrometry |
| US9653272B2 (en) | 2012-06-26 | 2017-05-16 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| WO2014152939A1 (en) | 2013-03-14 | 2014-09-25 | President And Fellows Of Harvard College | Methods and systems for identifying a physiological state of a target cell |
| WO2015105883A1 (en) | 2014-01-07 | 2015-07-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Apolipoprotein c biomarkers and methods for cholesterol efflux and cardiovascular health |
| WO2016006398A1 (ja) | 2014-07-07 | 2016-01-14 | 株式会社 日立ハイテクノロジーズ | 分析装置および分析方法 |
| JP2016156675A (ja) | 2015-02-24 | 2016-09-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び分析方法 |
| JP6839666B2 (ja) * | 2015-06-25 | 2021-03-10 | ネイティブ マイクロビアルズ， インコーポレイテッド | 複雑な異種群集由来微生物株の解析、機能的な関係及びそれらの相互作用の予測及び同定、ならびにそれに基づく微生物アンサンブルの選択及び合成のための方法、装置、及びシステム |
| EP4411387A3 (en) * | 2017-05-22 | 2024-11-13 | Beckman Coulter, Inc. | Integrated sample processing system with multiple detection capability |
-
2018
- 2018-05-22 EP EP24166653.6A patent/EP4411387A3/en active Pending
- 2018-05-22 US US16/616,052 patent/US11402386B2/en active Active
- 2018-05-22 WO PCT/US2018/033927 patent/WO2018217778A1/en not_active Ceased
- 2018-05-22 CN CN202310699080.3A patent/CN116825604A/zh active Pending
- 2018-05-22 JP JP2019564473A patent/JP2020521958A/ja not_active Withdrawn
- 2018-05-22 CN CN201880049114.1A patent/CN110959185B/zh active Active
- 2018-05-22 EP EP18731643.5A patent/EP3631839B1/en active Active
-
2022
- 2022-07-25 US US17/814,530 patent/US11988670B2/en active Active
-
2023
- 2023-03-10 JP JP2023037413A patent/JP7594618B2/ja active Active
-
2024
- 2024-04-09 US US18/630,611 patent/US20250027950A1/en active Pending
- 2024-07-16 JP JP2024113092A patent/JP2024133264A/ja active Pending
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