JP2020521958A - 複数の検出能力を有する統合試料処理システム - Google Patents

複数の検出能力を有する統合試料処理システム Download PDF

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Publication number
JP2020521958A
JP2020521958A JP2019564473A JP2019564473A JP2020521958A JP 2020521958 A JP2020521958 A JP 2020521958A JP 2019564473 A JP2019564473 A JP 2019564473A JP 2019564473 A JP2019564473 A JP 2019564473A JP 2020521958 A JP2020521958 A JP 2020521958A
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Prior art keywords
sample
aliquot
analyzer
mass spectrometer
analyte
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Japanese (ja)
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JP2020521958A5 (enExample
Inventor
アーロン ハドソン,
アーロン ハドソン,
貴行 水谷
貴行 水谷
サブハシシュ プルカヤスタ,
サブハシシュ プルカヤスタ,
トーマス ダブリュー. ロスコー,
トーマス ダブリュー. ロスコー,
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Beckman Coulter Inc
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Beckman Coulter Inc
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Publication of JP2020521958A publication Critical patent/JP2020521958A/ja
Publication of JP2020521958A5 publication Critical patent/JP2020521958A5/ja
Priority to JP2023037413A priority Critical patent/JP7594618B2/ja
Priority to JP2024113092A priority patent/JP2024133264A/ja
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • G01N27/624Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0031Step by step routines describing the use of the apparatus
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0036Step by step routines describing the handling of the data generated during a measurement
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/025Detectors specially adapted to particle spectrometers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2019564473A 2017-05-22 2018-05-22 複数の検出能力を有する統合試料処理システム Withdrawn JP2020521958A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023037413A JP7594618B2 (ja) 2017-05-22 2023-03-10 複数の検出能力を有する統合試料処理システム
JP2024113092A JP2024133264A (ja) 2017-05-22 2024-07-16 複数の検出能力を有する統合試料処理システム

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762509601P 2017-05-22 2017-05-22
US62/509,601 2017-05-22
US201762607773P 2017-12-19 2017-12-19
US62/607,773 2017-12-19
PCT/US2018/033927 WO2018217778A1 (en) 2017-05-22 2018-05-22 Integrated sample processing system with multiple detection capability

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023037413A Division JP7594618B2 (ja) 2017-05-22 2023-03-10 複数の検出能力を有する統合試料処理システム

Publications (2)

Publication Number Publication Date
JP2020521958A true JP2020521958A (ja) 2020-07-27
JP2020521958A5 JP2020521958A5 (enExample) 2021-07-26

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JP2019564473A Withdrawn JP2020521958A (ja) 2017-05-22 2018-05-22 複数の検出能力を有する統合試料処理システム
JP2023037413A Active JP7594618B2 (ja) 2017-05-22 2023-03-10 複数の検出能力を有する統合試料処理システム
JP2024113092A Pending JP2024133264A (ja) 2017-05-22 2024-07-16 複数の検出能力を有する統合試料処理システム

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JP2023037413A Active JP7594618B2 (ja) 2017-05-22 2023-03-10 複数の検出能力を有する統合試料処理システム
JP2024113092A Pending JP2024133264A (ja) 2017-05-22 2024-07-16 複数の検出能力を有する統合試料処理システム

Country Status (5)

Country Link
US (3) US11402386B2 (enExample)
EP (2) EP4411387A3 (enExample)
JP (3) JP2020521958A (enExample)
CN (2) CN116825604A (enExample)
WO (1) WO2018217778A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024501976A (ja) * 2020-12-30 2024-01-17 ベックマン コールター, インコーポレイテッド 単一の較正剤を用いた臨床検査室自動化システム

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4411387A3 (en) 2017-05-22 2024-11-13 Beckman Coulter, Inc. Integrated sample processing system with multiple detection capability
US11125738B2 (en) 2018-11-06 2021-09-21 Thermo Finnigan Llc Blood sample analysis systems and methods
WO2020129032A1 (en) * 2018-12-21 2020-06-25 Dh Technologies Development Pte. Ltd. Method for measuring testosterone using lc-msms
WO2020225971A1 (ja) 2019-05-08 2020-11-12 株式会社日立ハイテク 自動分析装置の前処理方法
JP7671510B2 (ja) 2019-09-25 2025-05-02 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー パルス・モード電荷検出質量分析のための装置および方法
EP4038361B1 (en) 2019-09-30 2024-06-19 DH Technologies Development Pte. Ltd. Sampling probe with internal sampling for use in mass spectrometry systems and methods
WO2021072186A1 (en) 2019-10-10 2021-04-15 The Trustees Of Indiana University System and method for identifying, selecting and purifying particles
CN113777332B (zh) * 2020-06-09 2024-06-18 深圳迈瑞生物医疗电子股份有限公司 免疫分析仪和自身免疫分析方法
CN117581104A (zh) * 2021-06-03 2024-02-20 Dh科技发展私人贸易有限公司 用于利用结合磁珠的质谱法进行样品处理的系统和方法
CN114047345B (zh) * 2021-11-09 2022-09-09 中元汇吉生物技术股份有限公司 一种样本优先调度方法、调度系统及检测系统
CN118235036A (zh) 2021-11-12 2024-06-21 贝克曼库尔特有限公司 用于表面增强拉曼光谱的系统和方法
CN116413253B (zh) * 2023-03-15 2025-10-10 宁波海尔施智造有限公司 一种人乳头瘤病毒检测试剂及其应用

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58628B2 (ja) * 1976-08-17 1983-01-07 株式会社島津製作所 自動分折装置
US20060159587A1 (en) * 2005-01-19 2006-07-20 Beckman Coulter, Inc. Automated clinical analyzer with dual level storage and access
JP2007000687A (ja) * 2005-06-21 2007-01-11 Shimadzu Corp 生体試料中のペプチド分析方法及び装置
JP2010175355A (ja) * 2009-01-29 2010-08-12 Hitachi High-Technologies Corp 自動分析装置
WO2010092958A1 (ja) * 2009-02-10 2010-08-19 株式会社日立ハイテクノロジーズ 質量分析技術を用いた免疫分析方法および免疫分析システム
JP2013541718A (ja) * 2010-10-29 2013-11-14 サーモ・フィッシャー・サイエンティフィック・オイ サンプルの準備および分析のための自動化されたシステム
WO2016006398A1 (ja) * 2014-07-07 2016-01-14 株式会社 日立ハイテクノロジーズ 分析装置および分析方法
JP2016156675A (ja) * 2015-02-24 2016-09-01 株式会社日立ハイテクノロジーズ 自動分析装置及び分析方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030027216A1 (en) 2001-07-02 2003-02-06 Kiernan Urban A. Analysis of proteins from biological fluids using mass spectrometric immunoassay
US6746648B1 (en) 2000-06-15 2004-06-08 Beckman Coulter, Inc. Method and system for transporting and storing multiple reagent packs and reagent packs used therein
US6843481B1 (en) 2000-10-10 2005-01-18 Beckman Coulter, Inc. Fluid-moving device with a clearance seal
US6520755B1 (en) 2000-10-10 2003-02-18 Beckman Coulter, Inc. Fluid-moving device with integrated valve
US7128874B2 (en) 2001-01-26 2006-10-31 Beckman Coulter, Inc. Method and system for picking and placing vessels
US6790412B2 (en) 2001-02-06 2004-09-14 Beckman Coulter, Inc. Bulk vessel feeder
US7217391B2 (en) 2001-03-16 2007-05-15 Beckman Coulter, Inc. Rotary incubation station for immunoassay systems
US6790413B2 (en) 2001-05-03 2004-09-14 Beckman Coulter, Inc. Sample presentation unit
US7632686B2 (en) 2002-10-03 2009-12-15 Anderson Forschung Group High sensitivity quantitation of peptides by mass spectrometry
WO2008005455A2 (en) 2006-07-03 2008-01-10 The Johns Hopkins University Peptide antibody depletion and its application to mass spectrometry sample preparation
CN104722342B (zh) * 2009-03-24 2017-01-11 芝加哥大学 滑动式芯片装置和方法
WO2011012657A1 (en) * 2009-07-29 2011-02-03 F. Hoffmann-La Roche Ag Automatic analyzer
EP2466308B1 (en) 2010-12-14 2018-02-07 Universitätsmedizin Greifswald Körperschaft des Öffentlichen Rechts Institut für Immunologie und Transfusionsmedizin Abteilung Immunologie Immunoassay device and use of the device (immunoassay)
WO2012170549A1 (en) 2011-06-06 2012-12-13 Waters Technologies Corporation Compositions, methods, and kits for quantifying target analytes in a sample
US9328386B2 (en) * 2011-08-16 2016-05-03 Evotec (München) Gmbh Markers for susceptibility to an inhibitor of an Src-family kinase
US9074236B2 (en) * 2012-05-01 2015-07-07 Oxoid Limited Apparatus and methods for microbial identification by mass spectrometry
US9653272B2 (en) 2012-06-26 2017-05-16 Biodesix, Inc. Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies
WO2014152939A1 (en) 2013-03-14 2014-09-25 President And Fellows Of Harvard College Methods and systems for identifying a physiological state of a target cell
WO2015105883A1 (en) 2014-01-07 2015-07-16 Arizona Board Of Regents On Behalf Of Arizona State University Apolipoprotein c biomarkers and methods for cholesterol efflux and cardiovascular health
JP6839666B2 (ja) * 2015-06-25 2021-03-10 ネイティブ マイクロビアルズ, インコーポレイテッド 複雑な異種群集由来微生物株の解析、機能的な関係及びそれらの相互作用の予測及び同定、ならびにそれに基づく微生物アンサンブルの選択及び合成のための方法、装置、及びシステム
EP4411387A3 (en) * 2017-05-22 2024-11-13 Beckman Coulter, Inc. Integrated sample processing system with multiple detection capability

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58628B2 (ja) * 1976-08-17 1983-01-07 株式会社島津製作所 自動分折装置
US20060159587A1 (en) * 2005-01-19 2006-07-20 Beckman Coulter, Inc. Automated clinical analyzer with dual level storage and access
JP2007000687A (ja) * 2005-06-21 2007-01-11 Shimadzu Corp 生体試料中のペプチド分析方法及び装置
JP2010175355A (ja) * 2009-01-29 2010-08-12 Hitachi High-Technologies Corp 自動分析装置
WO2010092958A1 (ja) * 2009-02-10 2010-08-19 株式会社日立ハイテクノロジーズ 質量分析技術を用いた免疫分析方法および免疫分析システム
JP2013541718A (ja) * 2010-10-29 2013-11-14 サーモ・フィッシャー・サイエンティフィック・オイ サンプルの準備および分析のための自動化されたシステム
WO2016006398A1 (ja) * 2014-07-07 2016-01-14 株式会社 日立ハイテクノロジーズ 分析装置および分析方法
JP2016156675A (ja) * 2015-02-24 2016-09-01 株式会社日立ハイテクノロジーズ 自動分析装置及び分析方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRIDON, GAELLE 外4名: ""Improvement of Phosphoproteome Analyses Using FAIMS and Decision Tree Fragmentation. Application t", JOURNAL OF PROTEOME RESEARCH, vol. 11, JPN6022012078, 7 November 2011 (2011-11-07), pages 927 - 940, ISSN: 0004918502 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024501976A (ja) * 2020-12-30 2024-01-17 ベックマン コールター, インコーポレイテッド 単一の較正剤を用いた臨床検査室自動化システム

Also Published As

Publication number Publication date
JP7594618B2 (ja) 2024-12-04
EP4411387A3 (en) 2024-11-13
US20250027950A1 (en) 2025-01-23
CN116825604A (zh) 2023-09-29
CN110959185A (zh) 2020-04-03
JP2023060337A (ja) 2023-04-27
US11988670B2 (en) 2024-05-21
US20210003586A1 (en) 2021-01-07
US20230011115A1 (en) 2023-01-12
EP3631839A1 (en) 2020-04-08
CN110959185B (zh) 2023-06-30
US11402386B2 (en) 2022-08-02
WO2018217778A1 (en) 2018-11-29
JP2024133264A (ja) 2024-10-01
EP4411387A2 (en) 2024-08-07
EP3631839B1 (en) 2024-04-03

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