JP2020521958A - 複数の検出能力を有する統合試料処理システム - Google Patents
複数の検出能力を有する統合試料処理システム Download PDFInfo
- Publication number
- JP2020521958A JP2020521958A JP2019564473A JP2019564473A JP2020521958A JP 2020521958 A JP2020521958 A JP 2020521958A JP 2019564473 A JP2019564473 A JP 2019564473A JP 2019564473 A JP2019564473 A JP 2019564473A JP 2020521958 A JP2020521958 A JP 2020521958A
- Authority
- JP
- Japan
- Prior art keywords
- sample
- aliquot
- analyzer
- mass spectrometer
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
- G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0031—Step by step routines describing the use of the apparatus
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/025—Detectors specially adapted to particle spectrometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0409—Sample holders or containers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023037413A JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762509601P | 2017-05-22 | 2017-05-22 | |
| US62/509,601 | 2017-05-22 | ||
| US201762607773P | 2017-12-19 | 2017-12-19 | |
| US62/607,773 | 2017-12-19 | ||
| PCT/US2018/033927 WO2018217778A1 (en) | 2017-05-22 | 2018-05-22 | Integrated sample processing system with multiple detection capability |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023037413A Division JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521958A true JP2020521958A (ja) | 2020-07-27 |
| JP2020521958A5 JP2020521958A5 (enExample) | 2021-07-26 |
Family
ID=62621016
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019564473A Withdrawn JP2020521958A (ja) | 2017-05-22 | 2018-05-22 | 複数の検出能力を有する統合試料処理システム |
| JP2023037413A Active JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A Pending JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023037413A Active JP7594618B2 (ja) | 2017-05-22 | 2023-03-10 | 複数の検出能力を有する統合試料処理システム |
| JP2024113092A Pending JP2024133264A (ja) | 2017-05-22 | 2024-07-16 | 複数の検出能力を有する統合試料処理システム |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11402386B2 (enExample) |
| EP (2) | EP4411387A3 (enExample) |
| JP (3) | JP2020521958A (enExample) |
| CN (2) | CN116825604A (enExample) |
| WO (1) | WO2018217778A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024501976A (ja) * | 2020-12-30 | 2024-01-17 | ベックマン コールター, インコーポレイテッド | 単一の較正剤を用いた臨床検査室自動化システム |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4411387A3 (en) | 2017-05-22 | 2024-11-13 | Beckman Coulter, Inc. | Integrated sample processing system with multiple detection capability |
| US11125738B2 (en) | 2018-11-06 | 2021-09-21 | Thermo Finnigan Llc | Blood sample analysis systems and methods |
| WO2020129032A1 (en) * | 2018-12-21 | 2020-06-25 | Dh Technologies Development Pte. Ltd. | Method for measuring testosterone using lc-msms |
| WO2020225971A1 (ja) | 2019-05-08 | 2020-11-12 | 株式会社日立ハイテク | 自動分析装置の前処理方法 |
| JP7671510B2 (ja) | 2019-09-25 | 2025-05-02 | ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー | パルス・モード電荷検出質量分析のための装置および方法 |
| EP4038361B1 (en) | 2019-09-30 | 2024-06-19 | DH Technologies Development Pte. Ltd. | Sampling probe with internal sampling for use in mass spectrometry systems and methods |
| WO2021072186A1 (en) | 2019-10-10 | 2021-04-15 | The Trustees Of Indiana University | System and method for identifying, selecting and purifying particles |
| CN113777332B (zh) * | 2020-06-09 | 2024-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 免疫分析仪和自身免疫分析方法 |
| CN117581104A (zh) * | 2021-06-03 | 2024-02-20 | Dh科技发展私人贸易有限公司 | 用于利用结合磁珠的质谱法进行样品处理的系统和方法 |
| CN114047345B (zh) * | 2021-11-09 | 2022-09-09 | 中元汇吉生物技术股份有限公司 | 一种样本优先调度方法、调度系统及检测系统 |
| CN118235036A (zh) | 2021-11-12 | 2024-06-21 | 贝克曼库尔特有限公司 | 用于表面增强拉曼光谱的系统和方法 |
| CN116413253B (zh) * | 2023-03-15 | 2025-10-10 | 宁波海尔施智造有限公司 | 一种人乳头瘤病毒检测试剂及其应用 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58628B2 (ja) * | 1976-08-17 | 1983-01-07 | 株式会社島津製作所 | 自動分折装置 |
| US20060159587A1 (en) * | 2005-01-19 | 2006-07-20 | Beckman Coulter, Inc. | Automated clinical analyzer with dual level storage and access |
| JP2007000687A (ja) * | 2005-06-21 | 2007-01-11 | Shimadzu Corp | 生体試料中のペプチド分析方法及び装置 |
| JP2010175355A (ja) * | 2009-01-29 | 2010-08-12 | Hitachi High-Technologies Corp | 自動分析装置 |
| WO2010092958A1 (ja) * | 2009-02-10 | 2010-08-19 | 株式会社日立ハイテクノロジーズ | 質量分析技術を用いた免疫分析方法および免疫分析システム |
| JP2013541718A (ja) * | 2010-10-29 | 2013-11-14 | サーモ・フィッシャー・サイエンティフィック・オイ | サンプルの準備および分析のための自動化されたシステム |
| WO2016006398A1 (ja) * | 2014-07-07 | 2016-01-14 | 株式会社 日立ハイテクノロジーズ | 分析装置および分析方法 |
| JP2016156675A (ja) * | 2015-02-24 | 2016-09-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び分析方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030027216A1 (en) | 2001-07-02 | 2003-02-06 | Kiernan Urban A. | Analysis of proteins from biological fluids using mass spectrometric immunoassay |
| US6746648B1 (en) | 2000-06-15 | 2004-06-08 | Beckman Coulter, Inc. | Method and system for transporting and storing multiple reagent packs and reagent packs used therein |
| US6843481B1 (en) | 2000-10-10 | 2005-01-18 | Beckman Coulter, Inc. | Fluid-moving device with a clearance seal |
| US6520755B1 (en) | 2000-10-10 | 2003-02-18 | Beckman Coulter, Inc. | Fluid-moving device with integrated valve |
| US7128874B2 (en) | 2001-01-26 | 2006-10-31 | Beckman Coulter, Inc. | Method and system for picking and placing vessels |
| US6790412B2 (en) | 2001-02-06 | 2004-09-14 | Beckman Coulter, Inc. | Bulk vessel feeder |
| US7217391B2 (en) | 2001-03-16 | 2007-05-15 | Beckman Coulter, Inc. | Rotary incubation station for immunoassay systems |
| US6790413B2 (en) | 2001-05-03 | 2004-09-14 | Beckman Coulter, Inc. | Sample presentation unit |
| US7632686B2 (en) | 2002-10-03 | 2009-12-15 | Anderson Forschung Group | High sensitivity quantitation of peptides by mass spectrometry |
| WO2008005455A2 (en) | 2006-07-03 | 2008-01-10 | The Johns Hopkins University | Peptide antibody depletion and its application to mass spectrometry sample preparation |
| CN104722342B (zh) * | 2009-03-24 | 2017-01-11 | 芝加哥大学 | 滑动式芯片装置和方法 |
| WO2011012657A1 (en) * | 2009-07-29 | 2011-02-03 | F. Hoffmann-La Roche Ag | Automatic analyzer |
| EP2466308B1 (en) | 2010-12-14 | 2018-02-07 | Universitätsmedizin Greifswald Körperschaft des Öffentlichen Rechts Institut für Immunologie und Transfusionsmedizin Abteilung Immunologie | Immunoassay device and use of the device (immunoassay) |
| WO2012170549A1 (en) | 2011-06-06 | 2012-12-13 | Waters Technologies Corporation | Compositions, methods, and kits for quantifying target analytes in a sample |
| US9328386B2 (en) * | 2011-08-16 | 2016-05-03 | Evotec (München) Gmbh | Markers for susceptibility to an inhibitor of an Src-family kinase |
| US9074236B2 (en) * | 2012-05-01 | 2015-07-07 | Oxoid Limited | Apparatus and methods for microbial identification by mass spectrometry |
| US9653272B2 (en) | 2012-06-26 | 2017-05-16 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| WO2014152939A1 (en) | 2013-03-14 | 2014-09-25 | President And Fellows Of Harvard College | Methods and systems for identifying a physiological state of a target cell |
| WO2015105883A1 (en) | 2014-01-07 | 2015-07-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Apolipoprotein c biomarkers and methods for cholesterol efflux and cardiovascular health |
| JP6839666B2 (ja) * | 2015-06-25 | 2021-03-10 | ネイティブ マイクロビアルズ, インコーポレイテッド | 複雑な異種群集由来微生物株の解析、機能的な関係及びそれらの相互作用の予測及び同定、ならびにそれに基づく微生物アンサンブルの選択及び合成のための方法、装置、及びシステム |
| EP4411387A3 (en) * | 2017-05-22 | 2024-11-13 | Beckman Coulter, Inc. | Integrated sample processing system with multiple detection capability |
-
2018
- 2018-05-22 EP EP24166653.6A patent/EP4411387A3/en active Pending
- 2018-05-22 US US16/616,052 patent/US11402386B2/en active Active
- 2018-05-22 WO PCT/US2018/033927 patent/WO2018217778A1/en not_active Ceased
- 2018-05-22 CN CN202310699080.3A patent/CN116825604A/zh active Pending
- 2018-05-22 JP JP2019564473A patent/JP2020521958A/ja not_active Withdrawn
- 2018-05-22 CN CN201880049114.1A patent/CN110959185B/zh active Active
- 2018-05-22 EP EP18731643.5A patent/EP3631839B1/en active Active
-
2022
- 2022-07-25 US US17/814,530 patent/US11988670B2/en active Active
-
2023
- 2023-03-10 JP JP2023037413A patent/JP7594618B2/ja active Active
-
2024
- 2024-04-09 US US18/630,611 patent/US20250027950A1/en active Pending
- 2024-07-16 JP JP2024113092A patent/JP2024133264A/ja active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58628B2 (ja) * | 1976-08-17 | 1983-01-07 | 株式会社島津製作所 | 自動分折装置 |
| US20060159587A1 (en) * | 2005-01-19 | 2006-07-20 | Beckman Coulter, Inc. | Automated clinical analyzer with dual level storage and access |
| JP2007000687A (ja) * | 2005-06-21 | 2007-01-11 | Shimadzu Corp | 生体試料中のペプチド分析方法及び装置 |
| JP2010175355A (ja) * | 2009-01-29 | 2010-08-12 | Hitachi High-Technologies Corp | 自動分析装置 |
| WO2010092958A1 (ja) * | 2009-02-10 | 2010-08-19 | 株式会社日立ハイテクノロジーズ | 質量分析技術を用いた免疫分析方法および免疫分析システム |
| JP2013541718A (ja) * | 2010-10-29 | 2013-11-14 | サーモ・フィッシャー・サイエンティフィック・オイ | サンプルの準備および分析のための自動化されたシステム |
| WO2016006398A1 (ja) * | 2014-07-07 | 2016-01-14 | 株式会社 日立ハイテクノロジーズ | 分析装置および分析方法 |
| JP2016156675A (ja) * | 2015-02-24 | 2016-09-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び分析方法 |
Non-Patent Citations (1)
| Title |
|---|
| BRIDON, GAELLE 外4名: ""Improvement of Phosphoproteome Analyses Using FAIMS and Decision Tree Fragmentation. Application t", JOURNAL OF PROTEOME RESEARCH, vol. 11, JPN6022012078, 7 November 2011 (2011-11-07), pages 927 - 940, ISSN: 0004918502 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024501976A (ja) * | 2020-12-30 | 2024-01-17 | ベックマン コールター, インコーポレイテッド | 単一の較正剤を用いた臨床検査室自動化システム |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7594618B2 (ja) | 2024-12-04 |
| EP4411387A3 (en) | 2024-11-13 |
| US20250027950A1 (en) | 2025-01-23 |
| CN116825604A (zh) | 2023-09-29 |
| CN110959185A (zh) | 2020-04-03 |
| JP2023060337A (ja) | 2023-04-27 |
| US11988670B2 (en) | 2024-05-21 |
| US20210003586A1 (en) | 2021-01-07 |
| US20230011115A1 (en) | 2023-01-12 |
| EP3631839A1 (en) | 2020-04-08 |
| CN110959185B (zh) | 2023-06-30 |
| US11402386B2 (en) | 2022-08-02 |
| WO2018217778A1 (en) | 2018-11-29 |
| JP2024133264A (ja) | 2024-10-01 |
| EP4411387A2 (en) | 2024-08-07 |
| EP3631839B1 (en) | 2024-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7594618B2 (ja) | 複数の検出能力を有する統合試料処理システム | |
| US12379370B2 (en) | Integrated sample processing system with variable workflows | |
| JP6538021B2 (ja) | サンプルの調製および分析のための自動化されたシステム | |
| JP2022070867A (ja) | 質量分析によるインスリンの定量 | |
| US20090090856A1 (en) | Methods and systems for quantification of peptides and other analytes | |
| US20170160273A1 (en) | Analysis device and analysis method | |
| US8865418B2 (en) | Immunoanalytical method and system using mass spectrometry technology | |
| US20250155448A1 (en) | Identification and quantitation of insulin-like growth factor-i variants by mass spectrometry | |
| US20240061001A1 (en) | Clinical laboratory automation system with single calibrator | |
| US20240420939A1 (en) | Ultra high throughput screening combined with definitive testing in a single sample preparation step | |
| US20230333130A1 (en) | System and Method for Disposing of a Reaction Vessel of a Mass Spectrometry System | |
| WO2024057238A1 (en) | Single tube sample preparation and calibration for both screening and quantification of analytes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210521 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210521 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20220323 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220331 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220629 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220830 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20221111 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230310 |
|
| C60 | Trial request (containing other claim documents, opposition documents) |
Free format text: JAPANESE INTERMEDIATE CODE: C60 Effective date: 20230310 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20230323 |
|
| C21 | Notice of transfer of a case for reconsideration by examiners before appeal proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C21 Effective date: 20230324 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20230328 |