CN116825604A - 样品处理系统和由其执行的方法 - Google Patents

样品处理系统和由其执行的方法 Download PDF

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Publication number
CN116825604A
CN116825604A CN202310699080.3A CN202310699080A CN116825604A CN 116825604 A CN116825604 A CN 116825604A CN 202310699080 A CN202310699080 A CN 202310699080A CN 116825604 A CN116825604 A CN 116825604A
Authority
CN
China
Prior art keywords
sample
aliquot
analyzer
mass spectrometer
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310699080.3A
Other languages
English (en)
Chinese (zh)
Inventor
阿伦·胡德松
水谷高雪
苏巴西什·普尔卡亚斯塔
托马斯·W·罗斯科
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DH Technologies Development Pte Ltd
Beckman Coulter Inc
Original Assignee
DH Technologies Development Pte Ltd
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DH Technologies Development Pte Ltd, Beckman Coulter Inc filed Critical DH Technologies Development Pte Ltd
Publication of CN116825604A publication Critical patent/CN116825604A/zh
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • G01N27/624Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0031Step by step routines describing the use of the apparatus
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • H01J49/0036Step by step routines describing the handling of the data generated during a measurement
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/025Detectors specially adapted to particle spectrometers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN202310699080.3A 2017-05-22 2018-05-22 样品处理系统和由其执行的方法 Pending CN116825604A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762509601P 2017-05-22 2017-05-22
US62/509,601 2017-05-22
US201762607773P 2017-12-19 2017-12-19
US62/607,773 2017-12-19
PCT/US2018/033927 WO2018217778A1 (en) 2017-05-22 2018-05-22 Integrated sample processing system with multiple detection capability
CN201880049114.1A CN110959185B (zh) 2017-05-22 2018-05-22 具有多种检测能力的集成样品处理系统

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201880049114.1A Division CN110959185B (zh) 2017-05-22 2018-05-22 具有多种检测能力的集成样品处理系统

Publications (1)

Publication Number Publication Date
CN116825604A true CN116825604A (zh) 2023-09-29

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201880049114.1A Active CN110959185B (zh) 2017-05-22 2018-05-22 具有多种检测能力的集成样品处理系统
CN202310699080.3A Pending CN116825604A (zh) 2017-05-22 2018-05-22 样品处理系统和由其执行的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201880049114.1A Active CN110959185B (zh) 2017-05-22 2018-05-22 具有多种检测能力的集成样品处理系统

Country Status (5)

Country Link
US (3) US11402386B2 (enExample)
EP (2) EP3631839B1 (enExample)
JP (3) JP2020521958A (enExample)
CN (2) CN110959185B (enExample)
WO (1) WO2018217778A1 (enExample)

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EP3899548A1 (en) * 2018-12-21 2021-10-27 DH Technologies Development Pte. Ltd. Method for measuring testosterone using lc-msms
WO2020225971A1 (ja) 2019-05-08 2020-11-12 株式会社日立ハイテク 自動分析装置の前処理方法
CN114667590B (zh) * 2019-09-25 2025-03-25 印地安纳大学理事会 用于脉冲模式电荷检测质谱法的设备和方法
CN114502942B (zh) 2019-09-30 2025-10-10 Dh科技发展私人贸易有限公司 用于在质谱法系统和方法中使用的具有内部取样的取样探针
WO2021072186A1 (en) 2019-10-10 2021-04-15 The Trustees Of Indiana University System and method for identifying, selecting and purifying particles
CN113777332B (zh) * 2020-06-09 2024-06-18 深圳迈瑞生物医疗电子股份有限公司 免疫分析仪和自身免疫分析方法
JP2024501976A (ja) * 2020-12-30 2024-01-17 ベックマン コールター, インコーポレイテッド 単一の較正剤を用いた臨床検査室自動化システム
US20240255473A1 (en) * 2021-06-03 2024-08-01 Dh Technologies Development Pte. Ltd. System and methods for sample processing with mass spectrometry incorporating magnetic beads
CN114047345B (zh) * 2021-11-09 2022-09-09 中元汇吉生物技术股份有限公司 一种样本优先调度方法、调度系统及检测系统
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CN116413253B (zh) * 2023-03-15 2025-10-10 宁波海尔施智造有限公司 一种人乳头瘤病毒检测试剂及其应用

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CN110959185B (zh) 2017-05-22 2023-06-30 拜克门寇尔特公司 具有多种检测能力的集成样品处理系统

Also Published As

Publication number Publication date
WO2018217778A1 (en) 2018-11-29
CN110959185A (zh) 2020-04-03
US20230011115A1 (en) 2023-01-12
JP2020521958A (ja) 2020-07-27
EP3631839A1 (en) 2020-04-08
US20250027950A1 (en) 2025-01-23
EP3631839B1 (en) 2024-04-03
US20210003586A1 (en) 2021-01-07
JP2023060337A (ja) 2023-04-27
EP4411387A3 (en) 2024-11-13
CN110959185B (zh) 2023-06-30
JP2024133264A (ja) 2024-10-01
EP4411387A2 (en) 2024-08-07
JP7594618B2 (ja) 2024-12-04
US11402386B2 (en) 2022-08-02
US11988670B2 (en) 2024-05-21

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