JP2020519668A5 - - Google Patents
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- JP2020519668A5 JP2020519668A5 JP2019563174A JP2019563174A JP2020519668A5 JP 2020519668 A5 JP2020519668 A5 JP 2020519668A5 JP 2019563174 A JP2019563174 A JP 2019563174A JP 2019563174 A JP2019563174 A JP 2019563174A JP 2020519668 A5 JP2020519668 A5 JP 2020519668A5
- Authority
- JP
- Japan
- Prior art keywords
- mir
- msc
- pharmaceutical composition
- aging
- exogenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762506661P | 2017-05-16 | 2017-05-16 | |
| US62/506,661 | 2017-05-16 | ||
| PCT/IL2018/050538 WO2018211510A1 (en) | 2017-05-16 | 2018-05-16 | Methods of inhibiting aging and treating aging-related disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020519668A JP2020519668A (ja) | 2020-07-02 |
| JP2020519668A5 true JP2020519668A5 (https=) | 2021-07-26 |
Family
ID=64273428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563174A Pending JP2020519668A (ja) | 2017-05-16 | 2018-05-16 | 老化の阻害および老化関連障害の治療の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20200188440A1 (https=) |
| EP (1) | EP3624817A4 (https=) |
| JP (1) | JP2020519668A (https=) |
| AU (1) | AU2018270408A1 (https=) |
| CA (1) | CA3064064A1 (https=) |
| WO (1) | WO2018211510A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3801028A4 (en) | 2018-05-30 | 2022-04-13 | Direct Biologics LLC | A growth factor and extracellular vesicle frozen or powdered additive comprising a mesenchymal stem cell (msc) preparation and methods of use |
| CN108753779B (zh) * | 2018-06-07 | 2021-12-14 | 天津农学院 | 牛lncRNA-133a及在牛骨骼肌卫星细胞增殖分化调控中的应用和验证方法 |
| US20220177921A1 (en) * | 2018-08-27 | 2022-06-09 | BioViva USA, Inc. | Gene therapy using genetically modified viral vectors |
| WO2020106997A1 (en) * | 2018-11-21 | 2020-05-28 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods and materials for reducing age-related striated muscle and cognitive decline |
| US12569517B2 (en) * | 2019-02-07 | 2026-03-10 | Direct Biologics, Llc | Method for treating osteoarthritis with mesenchymal stem cell exosomes |
| TWI722400B (zh) * | 2019-03-18 | 2021-03-21 | 佛教慈濟醫療財團法人 | 間質幹細胞之胞外泌體及其用途 |
| CN111218451B (zh) * | 2020-02-05 | 2021-08-10 | 华中农业大学 | 一种提高猪肌肉量的方法 |
| KR20230004709A (ko) | 2020-04-22 | 2023-01-06 | 다이렉트 바이오로직스 엘엘씨 | 감염성 질환과 연관된 염증성 병태를 치료하기 위한 방법 및 조성물 |
| KR102317052B1 (ko) * | 2020-05-04 | 2021-10-25 | 주식회사 티에스셀바이오 | 태반 유래의 세포외 소포의 항염증 항바이러스 효과 조성물 |
| CN111593114B (zh) * | 2020-05-29 | 2022-12-20 | 广东医科大学附属医院 | miR-122及其抑制剂在预防/治疗放射性脑损伤中的应用 |
| JP6967308B1 (ja) * | 2020-06-30 | 2021-11-17 | 国立大学法人高知大学 | 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 |
| CN112280742A (zh) * | 2020-11-05 | 2021-01-29 | 北京欣颂生物科技有限公司 | 干细胞制备的抗衰老的药物组合物或者保健品 |
| CN112089733B (zh) * | 2020-11-05 | 2021-03-12 | 广东赛尔生物科技有限公司 | 一种改造的脐带干细胞在制备抗衰老的药物组合物或者保健品中的用途 |
| WO2022102784A1 (ja) * | 2020-11-16 | 2022-05-19 | ヒューマンライフコード株式会社 | 筋肉量の低下抑制に用いる細胞調製物 |
| WO2022170056A1 (en) * | 2021-02-05 | 2022-08-11 | BioViva USA, Inc. | Systems and methods for gene therapy via administration of genetically modified viral vectors |
| KR102523933B1 (ko) * | 2021-05-03 | 2023-04-20 | 고려대학교 산학협력단 | 융모막 추출물로부터 분리된 엑소좀을 유효성분으로 포함하는 골형성 촉진용 약학적 조성물 |
| CN113981074A (zh) * | 2021-12-10 | 2022-01-28 | 石河子大学 | 一种与2型糖尿病相关的microRNA及其应用 |
| JP2023167026A (ja) * | 2022-05-11 | 2023-11-24 | 克昭 團 | 膵機能活性化剤、抗老化剤、2型糖尿病の治療薬または予防薬、医薬品、化粧品および食品または飲料 |
| CN115044543A (zh) * | 2022-08-17 | 2022-09-13 | 山东卓东生物科技有限公司 | 一种提高衰老人体来源肌肉干细胞活性的方法 |
| CN116926072B (zh) * | 2023-05-04 | 2024-03-08 | 广州飞来爱生命科技有限公司 | 一种抑制神经干细胞诱导分化方法及其应用 |
| US12502407B2 (en) | 2024-04-25 | 2025-12-23 | Direct Biologics, Llc | Treatment of fistula with bone marrow mesenchymal stem cell derived extracellular vesicles |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8192988B2 (en) * | 2004-10-22 | 2012-06-05 | University Of Central Florida Research Foundation, Inc. | Methods for increasing potency of adult mesenchymal stem cells |
| KR20120096793A (ko) * | 2011-02-23 | 2012-08-31 | (주)차바이오앤디오스텍 | 태반 유래 줄기세포를 포함한 면역반응억제용 조성물 |
| WO2013124817A2 (en) * | 2012-02-22 | 2013-08-29 | Brainstem Biotec Ltd. | MicroRNAS FOR THE GENERATION OF ASTROCYTES |
| KR101555981B1 (ko) * | 2013-05-01 | 2015-09-30 | 차의과학대학교 산학협력단 | 태반 유래 중간엽 줄기 세포, 또는 태반 유래 줄기세포로부터 유도된 신경 전구세포, 이를 포함하는 약학적 조성물, 질환 치료용 키트, 및 이를 이용하는 질환 치료방법 |
| EP3004328A4 (en) * | 2013-05-30 | 2016-12-07 | Cells For Cells | MESENCHYMAL STEM CELLS OF CHORIONIC ORIGIN, CONDITIONED MEDIUM AS AN ANGIOGENESIS INDUCER AND USE THEREOF FOR TREATMENT OF CARDIAC DEGENERATION |
| EP3140417B1 (en) * | 2014-05-09 | 2021-04-21 | Reelabs Private Limited | Foetal polymix of mesenchymal stem cells under hypoxic conditions for the treatment of clinical disorders |
| WO2016057755A1 (en) * | 2014-10-09 | 2016-04-14 | Anthrogenesis Corporation | Placenta-derived adherent cell exosomes and uses thereof |
| CN104560869B (zh) * | 2014-12-18 | 2018-02-23 | 江苏省北科生物科技有限公司 | 一种制备绒毛膜间充质干细胞的方法 |
| US20160324898A1 (en) * | 2015-05-04 | 2016-11-10 | Stemedica International, Sa | Compositions and methods for the treatment of alzheimer's disease |
| JP2019514416A (ja) * | 2016-05-16 | 2019-06-06 | エグゾステム バイオテック リミテッド | 間葉系幹細胞と筋損傷及び筋肉関連疾患の治療のための間葉系幹細胞の使用 |
| KR20190109389A (ko) * | 2016-11-03 | 2019-09-25 | 엑소스템 바이오텍 리미티드 | 간엽 줄기 세포 집단, 이들의 산물 및 이들의 용도 |
-
2018
- 2018-05-16 CA CA3064064A patent/CA3064064A1/en not_active Abandoned
- 2018-05-16 WO PCT/IL2018/050538 patent/WO2018211510A1/en not_active Ceased
- 2018-05-16 AU AU2018270408A patent/AU2018270408A1/en not_active Abandoned
- 2018-05-16 JP JP2019563174A patent/JP2020519668A/ja active Pending
- 2018-05-16 US US16/614,541 patent/US20200188440A1/en not_active Abandoned
- 2018-05-16 EP EP18802202.4A patent/EP3624817A4/en not_active Withdrawn
-
2024
- 2024-02-15 US US18/442,617 patent/US20240173354A1/en active Pending
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