JP2020519645A - 脂肪組織由来幹細胞による多発性硬化症の治療 - Google Patents

脂肪組織由来幹細胞による多発性硬化症の治療 Download PDF

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JP2020519645A
JP2020519645A JP2019562579A JP2019562579A JP2020519645A JP 2020519645 A JP2020519645 A JP 2020519645A JP 2019562579 A JP2019562579 A JP 2019562579A JP 2019562579 A JP2019562579 A JP 2019562579A JP 2020519645 A JP2020519645 A JP 2020519645A
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cells
adipose tissue
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マロム，エフド
グリンスパン，フリーダ
ユーディン，ディマ
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ステム セル メディスン リミテッド
ステム セル メディスン リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature

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  • Orthopedic Medicine & Surgery (AREA)
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  • Biochemistry (AREA)
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  • Hospice & Palliative Care (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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JP2019562579A 2017-05-15 2018-05-14 脂肪組織由来幹細胞による多発性硬化症の治療 Pending JP2020519645A (ja)

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US201762506006P 2017-05-15 2017-05-15
US62/506,006 2017-05-15
PCT/IL2018/050523 WO2018211498A1 (en) 2017-05-15 2018-05-14 Treatment of multiple sclerosis with adipose-derived stem cells

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US (1) US11510946B2 (https=)
EP (1) EP3624816A4 (https=)
JP (1) JP2020519645A (https=)
CN (1) CN110573170A (https=)
AU (1) AU2018270396B2 (https=)
CA (1) CA3062123A1 (https=)
IL (1) IL269893B2 (https=)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020519658A (ja) * 2017-05-15 2020-07-02 ステム セル メディスン リミテッド 長時間作用性グラチラマー及び脂肪由来幹細胞での多発性硬化症の治療
US11510946B2 (en) 2017-05-15 2022-11-29 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells

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Publication number Priority date Publication date Assignee Title
IL272145A (en) 2020-01-20 2021-07-29 Stem Cell Medicine Ltd Cosmetic compositions with protein concentrate from conditioned medium of adipose-derived stem cells
CN115624571A (zh) * 2022-12-21 2023-01-20 北京瑷格干细胞科技有限公司 人脂肪间充质干细胞在制备治疗硬皮病药物中的应用
CN115624570A (zh) * 2022-12-21 2023-01-20 北京瑷格干细胞科技有限公司 人脂肪间充质干细胞在制备治疗结缔组织疾病药物中的应用

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020519658A (ja) * 2017-05-15 2020-07-02 ステム セル メディスン リミテッド 長時間作用性グラチラマー及び脂肪由来幹細胞での多発性硬化症の治療
JP7000458B2 (ja) 2017-05-15 2022-02-10 ステム セル メディスン リミテッド 長時間作用性グラチラマー及び脂肪由来幹細胞での多発性硬化症の治療
US11413311B2 (en) 2017-05-15 2022-08-16 Mapi Pharma Ltd. Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells
US11510946B2 (en) 2017-05-15 2022-11-29 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells

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IL269893A (https=) 2019-11-28
CA3062123A1 (en) 2018-11-22
IL269893B2 (en) 2023-10-01
CN110573170A (zh) 2019-12-13
AU2018270396B2 (en) 2025-03-20
EP3624816A4 (en) 2021-02-24
US20200188439A1 (en) 2020-06-18
AU2018270396A1 (en) 2020-01-02
WO2018211498A1 (en) 2018-11-22
US11510946B2 (en) 2022-11-29
IL269893B1 (en) 2023-06-01
EP3624816A1 (en) 2020-03-25

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