IL269893B2 - Treatment of multiple sclerosis with adipose-derived stem cells - Google Patents
Treatment of multiple sclerosis with adipose-derived stem cellsInfo
- Publication number
- IL269893B2 IL269893B2 IL269893A IL26989319A IL269893B2 IL 269893 B2 IL269893 B2 IL 269893B2 IL 269893 A IL269893 A IL 269893A IL 26989319 A IL26989319 A IL 26989319A IL 269893 B2 IL269893 B2 IL 269893B2
- Authority
- IL
- Israel
- Prior art keywords
- hadscs
- cells
- pharmaceutical composition
- adscs
- administration
- Prior art date
Links
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K9/0012—Galenical forms characterised by the site of application
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| WO2018211486A1 (en) * | 2017-05-15 | 2018-11-22 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells |
| AU2018270396B2 (en) | 2017-05-15 | 2025-03-20 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with adipose-derived stem cells |
| IL272145A (en) | 2020-01-20 | 2021-07-29 | Stem Cell Medicine Ltd | Cosmetic compositions with protein concentrate from conditioned medium of adipose-derived stem cells |
| CN115624571A (zh) * | 2022-12-21 | 2023-01-20 | 北京瑷格干细胞科技有限公司 | 人脂肪间充质干细胞在制备治疗硬皮病药物中的应用 |
| CN115624570A (zh) * | 2022-12-21 | 2023-01-20 | 北京瑷格干细胞科技有限公司 | 人脂肪间充质干细胞在制备治疗结缔组织疾病药物中的应用 |
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| IL36670A (en) | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| IL113812A (en) | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
| US6214791B1 (en) | 1997-01-10 | 2001-04-10 | Yeda Research And Development Co. Ltd. | Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1 |
| PT1248643E (pt) | 2000-01-20 | 2005-10-31 | Yeda Res & Dev | Utilizacao de copolimero 1 e peptidos e polipeptidos congeneres e de celulas t tratadas co estes compostos para terapia neuroprotectora |
| US8871241B2 (en) | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
| NZ569331A (en) | 2003-01-21 | 2010-08-27 | Yeda Res & Dev | COP 1 for treatment of inflammatory bowel diseases |
| US7429378B2 (en) | 2003-05-13 | 2008-09-30 | Depuy Spine, Inc. | Transdiscal administration of high affinity anti-MMP inhibitors |
| AU2005308396B2 (en) | 2004-11-29 | 2011-06-09 | Yeda Research And Development Co. Ltd. | Induction of neurogenesis and stem cell therapy in combination with Copolymer 1 |
| WO2006060779A2 (en) | 2004-12-03 | 2006-06-08 | Case Western Reserve University | Novel methods, compositions and devices for inducing neovascularization |
| JP4654015B2 (ja) | 2004-12-08 | 2011-03-16 | 京セラ株式会社 | カメラ装置 |
| US20070003528A1 (en) | 2005-06-29 | 2007-01-04 | Paul Consigny | Intracoronary device and method of use thereof |
| NZ597304A (en) | 2005-10-13 | 2013-06-28 | Anthrogenesis Corp | Immunomodulation using placental stem cells |
| EP1795588A1 (en) | 2005-12-07 | 2007-06-13 | Cellerix, S.L. | Use of adipose tissue derived mesenchymal stem cells for the treatment of graft versus host disease |
| WO2008024996A2 (en) | 2006-08-24 | 2008-02-28 | Johnstone Brian H | Production of neural protective and regenerative factors from stem cells and treatment of nervous system conditions therewith |
| WO2008057443A2 (en) | 2006-11-03 | 2008-05-15 | Multiple Sclerosis Research Center Of New York | Bone marrow-derived mesenchymal stem cells as a source of neural progenitors |
| WO2011041240A1 (en) | 2009-09-30 | 2011-04-07 | The Brigham And Women's Hospital, Inc. | Tissue transplant compositions and methods for use |
| US8703180B1 (en) | 2007-10-23 | 2014-04-22 | Abbott Cardiovascular Systems Inc. | Multiple growth factor compositions, methods of fabrication, and methods of treatment |
| US8481253B2 (en) * | 2008-03-19 | 2013-07-09 | Cryo-Save Ag | Cryopreservation of adipose tissue for the isolation of mesenchymal stem cells |
| US20090291061A1 (en) | 2008-05-21 | 2009-11-26 | Riordan Neil H | Stem cell therapy for blood vessel degeneration |
| EP2620493B1 (en) | 2008-05-28 | 2019-03-27 | Ramot at Tel Aviv University Ltd. | Mesenchymal stem cells for the treatment of CNS diseases |
| US20110129450A1 (en) | 2008-08-01 | 2011-06-02 | Orly Lazarov | Method of promoting neurogenesis by modulating secretase activities |
| WO2010028051A2 (en) | 2008-09-03 | 2010-03-11 | Florida State University Research Foundation, Inc. | Substituted heterocyclic mercaptosulfonamide metalloprotease inhibitors |
| CN102186968A (zh) | 2008-10-17 | 2011-09-14 | 巴克斯特国际公司 | 从脂肪组织获得细胞群的方法 |
| JP5515319B2 (ja) | 2009-02-23 | 2014-06-11 | 富士レビオ株式会社 | 脂肪細胞への分化誘導培地及び方法 |
| CA2767300C (en) | 2009-07-09 | 2020-01-07 | Cellerix Sa | Methods and compositions for use in cellular therapies |
| US8377885B2 (en) | 2010-01-04 | 2013-02-19 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| JP5916622B2 (ja) | 2010-01-04 | 2016-05-11 | マピ ファーマ リミテッド | グラチラマーまたはその薬理学的に許容される塩を含むデポーシステム |
| EP3351625A1 (en) | 2010-02-18 | 2018-07-25 | Osiris Therapeutics, Inc. | Methods of manufacture of immunocompatible amniotic membrane products |
| ES2601892T3 (es) | 2011-04-21 | 2017-02-16 | Mapi Pharma Limited | Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes |
| US20130034524A1 (en) | 2011-08-03 | 2013-02-07 | Siamak Agha-Mohammadi | Non-Enzymatic Method for Harvesting Adipose-Derived Stromal Cells and Adipose-Derived Stem Cells from Fat and Lipo-Aspirate |
| DK2744892T3 (en) | 2011-09-23 | 2019-04-23 | Cell Ideas Pty Ltd | THERAPEUTICS USING FAT CELLS AND CELL SECRETIONS |
| CL2011002642A1 (es) | 2011-10-24 | 2012-04-09 | Univ Del Desarrollo | Uso de una composicion formada por un glucocorticoide y una tiazolinediona que sirve para inducir la diferenciacion adipogenica en celulas madres. |
| EP2623110A1 (en) | 2012-01-31 | 2013-08-07 | CSL Behring GmbH | Factor XII inhibitors for the treatment of neurological inflammatory disorders |
| EP2825638A4 (en) | 2012-03-12 | 2015-11-25 | Univ Singapore | GENERATION OF BROWN FAT FABRIC FROM MESENCYCLES |
| CN104130975B (zh) * | 2013-05-03 | 2018-07-17 | 上海市东方医院 | 人源脂肪干细胞来源的神经元样细胞及其制备方法和应用 |
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| WO2015120388A1 (en) * | 2014-02-10 | 2015-08-13 | Cytori Therapeutics, Inc. | Regenerative cell therapy for central nervous system (cns) disorders and ptsd |
| CN109072189A (zh) | 2016-02-12 | 2018-12-21 | 细胞治疗药物公司 | 脂肪组织衍生的间充质基质细胞条件培养基及其制备和使用方法 |
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| AU2018270396B2 (en) | 2017-05-15 | 2025-03-20 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with adipose-derived stem cells |
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| STEPIEN, A. ET AL., CLINICAL APPLICATION OF AUTOLOGOUS ADIPOSE STEM CELLS IN PATIENTS WITH MULTIPLE SCLEROSIS: PRELIMINARY RESULTS., 28 September 2016 (2016-09-28) * |
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Also Published As
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| IL269893A (https=) | 2019-11-28 |
| CA3062123A1 (en) | 2018-11-22 |
| CN110573170A (zh) | 2019-12-13 |
| AU2018270396B2 (en) | 2025-03-20 |
| EP3624816A4 (en) | 2021-02-24 |
| JP2020519645A (ja) | 2020-07-02 |
| US20200188439A1 (en) | 2020-06-18 |
| AU2018270396A1 (en) | 2020-01-02 |
| WO2018211498A1 (en) | 2018-11-22 |
| US11510946B2 (en) | 2022-11-29 |
| IL269893B1 (en) | 2023-06-01 |
| EP3624816A1 (en) | 2020-03-25 |
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