JP2020518553A5 - - Google Patents
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- Publication number
- JP2020518553A5 JP2020518553A5 JP2019544928A JP2019544928A JP2020518553A5 JP 2020518553 A5 JP2020518553 A5 JP 2020518553A5 JP 2019544928 A JP2019544928 A JP 2019544928A JP 2019544928 A JP2019544928 A JP 2019544928A JP 2020518553 A5 JP2020518553 A5 JP 2020518553A5
- Authority
- JP
- Japan
- Prior art keywords
- layer
- therapeutic system
- transdermal therapeutic
- active substance
- nicotine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010410 layer Substances 0.000 claims 53
- 230000001225 therapeutic effect Effects 0.000 claims 29
- 239000011159 matrix material Substances 0.000 claims 21
- 239000013543 active substance Substances 0.000 claims 18
- 238000000034 method Methods 0.000 claims 14
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 13
- 229960002715 nicotine Drugs 0.000 claims 13
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 9
- 239000012790 adhesive layer Substances 0.000 claims 8
- 229920001577 copolymer Polymers 0.000 claims 8
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical group NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 7
- 230000007246 mechanism Effects 0.000 claims 7
- 125000000524 functional group Chemical group 0.000 claims 6
- 239000011241 protective layer Substances 0.000 claims 6
- 230000009969 flowable effect Effects 0.000 claims 5
- 238000004873 anchoring Methods 0.000 claims 4
- 239000000853 adhesive Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000007639 printing Methods 0.000 claims 3
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 238000005520 cutting process Methods 0.000 claims 2
- 239000012458 free base Substances 0.000 claims 2
- 238000010030 laminating Methods 0.000 claims 2
- 230000007935 neutral effect Effects 0.000 claims 2
- 229920000728 polyester Polymers 0.000 claims 2
- -1 polyethylene terephthalate Polymers 0.000 claims 2
- 230000001681 protective effect Effects 0.000 claims 2
- 230000000087 stabilizing effect Effects 0.000 claims 2
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 claims 1
- 239000004831 Hot glue Substances 0.000 claims 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical class COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 229920002367 Polyisobutene Polymers 0.000 claims 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 claims 1
- 229920003118 cationic copolymer Polymers 0.000 claims 1
- 238000002845 discoloration Methods 0.000 claims 1
- 238000009826 distribution Methods 0.000 claims 1
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 150000003951 lactams Chemical group 0.000 claims 1
- 239000002648 laminated material Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 125000005397 methacrylic acid ester group Chemical group 0.000 claims 1
- 229920003052 natural elastomer Polymers 0.000 claims 1
- 229920001194 natural rubber Polymers 0.000 claims 1
- 238000007649 pad printing Methods 0.000 claims 1
- 229920001084 poly(chloroprene) Polymers 0.000 claims 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 1
- 229920001707 polybutylene terephthalate Polymers 0.000 claims 1
- 229920000139 polyethylene terephthalate Polymers 0.000 claims 1
- 239000005020 polyethylene terephthalate Substances 0.000 claims 1
- 229920000193 polymethacrylate Polymers 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 229920002689 polyvinyl acetate Polymers 0.000 claims 1
- 229920001289 polyvinyl ether Polymers 0.000 claims 1
- 229920003048 styrene butadiene rubber Polymers 0.000 claims 1
- 229920003051 synthetic elastomer Polymers 0.000 claims 1
- 239000005061 synthetic rubber Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102017104026.9 | 2017-02-27 | ||
| DE102017104026.9A DE102017104026A1 (de) | 2017-02-27 | 2017-02-27 | Nicotin enthaltendes transparentes transdermales therapeutisches System |
| PCT/DE2018/100168 WO2018153413A1 (de) | 2017-02-27 | 2018-02-26 | Nicotin enthaltendes transparentes transdermales therapeutisches system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020518553A JP2020518553A (ja) | 2020-06-25 |
| JP2020518553A5 true JP2020518553A5 (enExample) | 2020-08-27 |
| JP7149951B2 JP7149951B2 (ja) | 2022-10-07 |
Family
ID=61837471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019544928A Active JP7149951B2 (ja) | 2017-02-27 | 2018-02-26 | ニコチン含有透明経皮吸収治療システム |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11964060B2 (enExample) |
| EP (1) | EP3585440B1 (enExample) |
| JP (1) | JP7149951B2 (enExample) |
| KR (1) | KR20190120263A (enExample) |
| CN (1) | CN110325216A (enExample) |
| AU (1) | AU2018226365A1 (enExample) |
| CA (1) | CA3051150C (enExample) |
| DE (1) | DE102017104026A1 (enExample) |
| ES (1) | ES2897449T3 (enExample) |
| MX (1) | MX2019009781A (enExample) |
| RU (1) | RU2019127802A (enExample) |
| WO (1) | WO2018153413A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102019117310A1 (de) * | 2019-06-27 | 2020-12-31 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Herstellung von Wirkstoffverabreichungssystemen mittels Tampondruckverfahren |
| KR102477606B1 (ko) | 2022-07-02 | 2022-12-14 | 주식회사 아이써치마케팅 | Sns 빅데이터 분석 시스템 |
| KR102477604B1 (ko) | 2022-07-02 | 2022-12-14 | 주식회사 아이써치마케팅 | 온라인 마케팅 빅데이터 분석 시스템 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59196817A (ja) * | 1983-04-21 | 1984-11-08 | Sekisui Chem Co Ltd | 貼付剤 |
| DE3727232A1 (de) | 1987-08-14 | 1989-02-23 | Lohmann Therapie Syst Lts | Verfahren zur herstellung einer darreichungs- und/oder dosierungsform fuer arzneimittelwirkstoffe |
| US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US4908213A (en) | 1989-02-21 | 1990-03-13 | Schering Corporation | Transdermal delivery of nicotine |
| US5508038A (en) | 1990-04-16 | 1996-04-16 | Alza Corporation | Polyisobutylene adhesives for transdermal devices |
| DE4400769C2 (de) | 1994-01-13 | 1996-07-18 | Lohmann Therapie Syst Lts | Verfahren und Vorrichtung zur Herstellung einer flächigen Darreichungsform mit einer Arzneimittelwirkstoffe enthaltenden Zubereitung |
| FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
| WO1999015210A2 (en) | 1997-09-26 | 1999-04-01 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
| PT1140039E (pt) * | 1998-12-18 | 2010-02-03 | Alza Corp | Dispositivos transparentes de administração transdérmica de nicotina |
| DE19912477A1 (de) * | 1999-03-19 | 2000-09-28 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| AU779523B2 (en) | 1999-11-29 | 2005-01-27 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic systems with improved stability and a method for the production thereof |
| US6479076B2 (en) | 2001-01-12 | 2002-11-12 | Izhak Blank | Nicotine delivery compositions |
| DE10304988A1 (de) * | 2003-02-07 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten |
| RU2263503C1 (ru) | 2004-04-23 | 2005-11-10 | Каш Тенгиз | Способ получения препарата и препарат для трансдермального введения никотина |
| DE102004062614B4 (de) * | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
| DE102005010255A1 (de) * | 2005-03-07 | 2006-09-14 | Lts Lohmann Therapie-Systeme Ag | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| JP5000910B2 (ja) | 2006-03-29 | 2012-08-15 | リンテック株式会社 | 貼付剤及びその製造方法 |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| RU2320674C1 (ru) | 2006-07-12 | 2008-03-27 | Каш Тенгис | Способ получения сополимера n-винилпирролидона с лаурилметакрилатом для трансдермального введения никотина, сополимер, полученный этим способом, гель для трансдермального введения никотина |
| RU2356553C2 (ru) | 2007-04-06 | 2009-05-27 | Каш Тенгис | Способ получения препарата и препарат для трансдермального введения никотина |
| WO2009141321A2 (en) | 2008-05-21 | 2009-11-26 | Novartis Ag | Tablettable chewing gums |
| GB201100790D0 (en) | 2011-01-18 | 2011-03-02 | Kraft Foods Global Brands Llc | Hydrophilic gum base |
| JP5725940B2 (ja) * | 2011-04-01 | 2015-05-27 | 日東電工株式会社 | ニコチン含有貼付製剤 |
| EP3007685A1 (de) * | 2013-06-14 | 2016-04-20 | tesa Labtec GmbH | Dreischichtiges transdermales therapiesystem (tts) |
| DE102014000200A1 (de) | 2014-01-03 | 2015-07-09 | Michael Horstmann | Transdermales Therapeutisches System |
-
2017
- 2017-02-27 DE DE102017104026.9A patent/DE102017104026A1/de not_active Withdrawn
-
2018
- 2018-02-26 EP EP18714674.1A patent/EP3585440B1/de active Active
- 2018-02-26 RU RU2019127802A patent/RU2019127802A/ru unknown
- 2018-02-26 AU AU2018226365A patent/AU2018226365A1/en not_active Abandoned
- 2018-02-26 US US16/488,506 patent/US11964060B2/en active Active
- 2018-02-26 CA CA3051150A patent/CA3051150C/en active Active
- 2018-02-26 MX MX2019009781A patent/MX2019009781A/es unknown
- 2018-02-26 WO PCT/DE2018/100168 patent/WO2018153413A1/de not_active Ceased
- 2018-02-26 JP JP2019544928A patent/JP7149951B2/ja active Active
- 2018-02-26 CN CN201880012781.2A patent/CN110325216A/zh active Pending
- 2018-02-26 ES ES18714674T patent/ES2897449T3/es active Active
- 2018-02-26 KR KR1020197027049A patent/KR20190120263A/ko not_active Withdrawn
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