JP2020517703A - アミノ酸組成物及び外傷性脳損傷の治療のためのそれらの使用 - Google Patents

アミノ酸組成物及び外傷性脳損傷の治療のためのそれらの使用 Download PDF

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Publication number
JP2020517703A
JP2020517703A JP2019558411A JP2019558411A JP2020517703A JP 2020517703 A JP2020517703 A JP 2020517703A JP 2019558411 A JP2019558411 A JP 2019558411A JP 2019558411 A JP2019558411 A JP 2019558411A JP 2020517703 A JP2020517703 A JP 2020517703A
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Prior art keywords
amino acid
composition
leucine
isoleucine
valine
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JP2019558411A
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Japanese (ja)
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JP2020517703A5 (https=
Inventor
キャロル，ショーン
アフェヤン，ラフィー
リエンツォ，ジャンルカ デ
リエンツォ，ジャンルカ デ
ルーセル，マシュー
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Axcella Health Inc
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Axcella Health Inc
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Publication of JP2020517703A publication Critical patent/JP2020517703A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019558411A 2017-04-28 2018-04-27 アミノ酸組成物及び外傷性脳損傷の治療のためのそれらの使用 Pending JP2020517703A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762491796P 2017-04-28 2017-04-28
US62/491,796 2017-04-28
PCT/US2018/029908 WO2018201024A1 (en) 2017-04-28 2018-04-27 Amino acid compositions and their use for the treatment of traumatic brain injury

Publications (2)

Publication Number Publication Date
JP2020517703A true JP2020517703A (ja) 2020-06-18
JP2020517703A5 JP2020517703A5 (https=) 2021-06-17

Family

ID=62165694

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019558411A Pending JP2020517703A (ja) 2017-04-28 2018-04-27 アミノ酸組成物及び外傷性脳損傷の治療のためのそれらの使用

Country Status (5)

Country Link
US (1) US11617731B2 (https=)
EP (1) EP3615018A1 (https=)
JP (1) JP2020517703A (https=)
CN (1) CN110678172A (https=)
WO (1) WO2018201024A1 (https=)

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JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
WO2018201024A1 (en) 2017-04-28 2018-11-01 Axcella Health Inc. Amino acid compositions and their use for the treatment of traumatic brain injury
IT201700087359A1 (it) 2017-07-28 2019-01-28 Professional Dietetics Spa Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale
MX2020001765A (es) 2017-08-14 2020-07-29 Axcella Health Inc Composiciones de aminoacidos para el tratamiento de enfermedad hepatica.
JP2021529735A (ja) 2018-06-20 2021-11-04 アクセラ・ヘルス・インコーポレイテッドＡｘｃｅｌｌａ Ｈｅａｌｔｈ Ｉｎｃ． アミノ酸組成物の製造方法
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
CN112839643A (zh) 2018-06-20 2021-05-25 胺细拉健康公司 用于治疗肌肉中脂肪浸润的组合物及方法
IT201800006725A1 (it) 2018-06-27 2019-12-27 Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche
IT201900002109A1 (it) * 2019-02-13 2020-08-13 Professional Dietetics Spa Composizioni comprendenti amminoacidi per l'uso nel trattamento di lesioni del sistema nervoso centrale
IT202000000442A1 (it) 2020-01-13 2021-07-13 Professional Dietetics Spa Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia
US20220218640A1 (en) * 2021-01-14 2022-07-14 Rob Dickerman Amino acid delivery system
WO2023009444A1 (en) 2021-07-26 2023-02-02 Axcella Health Inc. Amino acid compositions and methods for use in the treatment of post-acute sequelae of covid-19
CN119235838A (zh) * 2024-11-04 2025-01-03 苏州市立医院 一种hmb在制备改善创伤性脑损伤药物中的应用

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JP2004123564A (ja) * 2002-09-30 2004-04-22 Inst Of Physical & Chemical Res 中枢機能改善用アミノ酸組成物
JP2009106217A (ja) * 2007-10-31 2009-05-21 Ajinomoto Co Inc 増粘剤とアミノ酸を含有する食品組成物
US20140170211A1 (en) * 2012-12-18 2014-06-19 Matthew Bennett Compositions and methods for treating traumatic brain injury

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JP7370960B2 (ja) 2017-08-14 2023-10-30 アクセラ・ヘルス・インコーポレイテッド 神経細胞損傷の治療のためのアミノ酸組成物
MX2020001765A (es) 2017-08-14 2020-07-29 Axcella Health Inc Composiciones de aminoacidos para el tratamiento de enfermedad hepatica.
JP2021529735A (ja) 2018-06-20 2021-11-04 アクセラ・ヘルス・インコーポレイテッドＡｘｃｅｌｌａ Ｈｅａｌｔｈ Ｉｎｃ． アミノ酸組成物の製造方法
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
WO2019246221A1 (en) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions and methods for the treatment of liver diseases and disorders
CN112839643A (zh) 2018-06-20 2021-05-25 胺细拉健康公司 用于治疗肌肉中脂肪浸润的组合物及方法
MX2020013731A (es) 2018-06-20 2021-02-26 Axcella Health Inc Composiciones para terapia y salud que contienen aminoacidos con sabor amargo.

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JP2004123564A (ja) * 2002-09-30 2004-04-22 Inst Of Physical & Chemical Res 中枢機能改善用アミノ酸組成物
JP2009106217A (ja) * 2007-10-31 2009-05-21 Ajinomoto Co Inc 増粘剤とアミノ酸を含有する食品組成物
US20140170211A1 (en) * 2012-12-18 2014-06-19 Matthew Bennett Compositions and methods for treating traumatic brain injury

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
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Also Published As

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US11617731B2 (en) 2023-04-04
EP3615018A1 (en) 2020-03-04
US20200163919A1 (en) 2020-05-28
WO2018201024A1 (en) 2018-11-01
CN110678172A (zh) 2020-01-10

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