|
US2010129A
(en)
|
1934-09-26 |
1935-08-06 |
Ingersoll Rand Co |
Valve assembly
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
ES2341666T3
(es)
|
1991-12-02 |
2010-06-24 |
Medimmune Limited |
Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
|
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US20080152586A1
(en)
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
|
US6355780B1
(en)
|
1995-02-22 |
2002-03-12 |
Yeda Research And Development Co. Ltd. |
Antibodies to the death domain motifs of regulatory proteins
|
|
ES2194209T3
(es)
|
1996-07-22 |
2003-11-16 |
Monsanto Co |
Inhibidores de metaloproteasa de tiol sulfona.
|
|
CA2297070A1
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
US7115396B2
(en)
|
1998-12-10 |
2006-10-03 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
ES2276708T3
(es)
|
1999-11-24 |
2007-07-01 |
Immunogen, Inc. |
Agentes citotoxicos que comprenden taxanos y su uso terapeutico.
|
|
ATE367374T1
(de)
|
2000-07-19 |
2007-08-15 |
Mitsubishi Pharma Corp |
Sulphonsäurederivate von hydroxamsäuren und deren verwendung in medizinischen produkten
|
|
DE60140474D1
(de)
|
2000-09-08 |
2009-12-24 |
Univ Zuerich |
Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
US20030109682A1
(en)
*
|
2001-09-07 |
2003-06-12 |
Daniel Santi |
Maytansines and maytansine conjugates
|
|
WO2003034903A2
(en)
|
2001-10-23 |
2003-05-01 |
Psma Development Company, L.L.C. |
Psma antibodies and protein multimers
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US6756397B2
(en)
|
2002-04-05 |
2004-06-29 |
Immunogen, Inc. |
Prodrugs of CC-1065 analogs
|
|
CN100522955C
(zh)
|
2002-08-02 |
2009-08-05 |
伊缪诺金公司 |
含有新型强效紫杉烷的细胞毒性剂及其治疗用途
|
|
JP2006500364A
(ja)
|
2002-08-16 |
2006-01-05 |
イムノージェン インコーポレーテッド |
高い反応性と溶解度を有する架橋剤および小分子薬物の標的化送達用コンジュゲートの調製におけるそれらの使用
|
|
BR0316101A
(pt)
|
2002-11-07 |
2005-09-27 |
Immunogen Inc |
Anticorpos anticd33 e processo para tratamento de leucemia melóide aguda usando os mesmos
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
PL3524611T3
(pl)
|
2003-05-20 |
2021-06-14 |
Immunogen, Inc. |
Udoskonalone czynniki cytotoksyczne zawierające nowe maitansynoidy
|
|
US7834155B2
(en)
|
2003-07-21 |
2010-11-16 |
Immunogen Inc. |
CA6 antigen-specific cytotoxic conjugate and methods of using the same
|
|
EA014640B1
(ru)
|
2003-07-21 |
2010-12-30 |
Иммьюноджен, Инк. |
Антитело или его эпитоп-связывающий фрагмент, которые связываются с гликотопом са6, и способы их применения
|
|
EP3225633B1
(en)
|
2004-05-21 |
2020-03-25 |
The UAB Research Foundation |
Variable lymphocyte receptors, related polypeptides and nucleic acids, and uses thereof
|
|
KR20120064120A
(ko)
|
2004-06-01 |
2012-06-18 |
제넨테크, 인크. |
항체 약물 접합체 및 방법
|
|
EP1817341A2
(en)
|
2004-11-29 |
2007-08-15 |
Seattle Genetics, Inc. |
Engineered antibodies and immunoconjugates
|
|
BRPI0613593A2
(pt)
|
2005-07-08 |
2011-01-18 |
Univ Zuerich |
método de teste "phage display" filamentoso, vetor de fago ou de fagomìdeo e biblioteca de vetores de fago ou fagomìdeo
|
|
MX2008002607A
(es)
|
2005-08-22 |
2008-03-19 |
Immunogen Inc |
Un conjugado citotoxico ca6 antigeno-especifico y metodos para utilizar el mismo.
|
|
WO2007062466A1
(en)
|
2005-11-29 |
2007-06-07 |
The University Of Sydney |
Demibodies: dimerisation-activated therapeutic agents
|
|
US7897568B2
(en)
|
2006-03-03 |
2011-03-01 |
Vinay K. Singh |
Compositions for treatment of cancer
|
|
ES2567402T3
(es)
|
2006-05-30 |
2016-04-22 |
Genentech, Inc. |
Anticuerpos anti CD22, sus inmunoconjugados y usos de los mismos
|
|
CA2655379A1
(en)
|
2006-06-22 |
2007-12-27 |
Walter And Eliza Hall Institute Of Medical Research |
Structure of the insulin receptor ectodomain
|
|
CA2700391A1
(en)
|
2007-09-24 |
2009-04-02 |
University Of Zuerich |
Designed armadillo repeat proteins
|
|
KR20200058590A
(ko)
|
2008-04-30 |
2020-05-27 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
EP2276506A4
(en)
|
2008-04-30 |
2014-05-07 |
Immunogen Inc |
EFFICIENT CONJUGATES AND HYDROPHILIC BINDER
|
|
BRPI0919881B1
(pt)
|
2008-10-31 |
2021-09-08 |
Centocor Ortho Biotech Inc |
Proteína de arcabouço e seu método de geração, biblioteca e seu método de construção, molécula de ácido nucleico, vetor de ácido nucleico, célula hospedeira, composição, dispositivo médico e artigo de fabricação
|
|
GB0913775D0
(en)
|
2009-08-06 |
2009-09-16 |
Medical Res Council |
Multispecific peptides
|
|
BRPI1008532B1
(pt)
|
2009-02-12 |
2021-12-14 |
Janssen Biotech, Inc |
Arcabouço de proteína isolada, método para construção de uma biblioteca de arcabouço de proteína isolada, molécula de ácido nucleico isolada, vetor de ácido nucleico isolado, célula hospedeira de bactéria ou fungo, composição, dispositivo médico e artigo de manufatura para uso farmacêutico ou de diagnóstico em seres humanos
|
|
SG181814A1
(en)
|
2009-12-23 |
2012-07-30 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them 2
|
|
CN103037900B
(zh)
|
2010-02-24 |
2016-04-06 |
伊缪诺金公司 |
叶酸受体1抗体与免疫缀合物以及其用途
|
|
SG183542A1
(en)
|
2010-03-12 |
2012-10-30 |
Immunogen Inc |
Cd37-binding molecules and immunoconjugates thereof
|
|
EP3569256B1
(en)
|
2010-04-30 |
2022-06-15 |
Janssen Biotech, Inc. |
Stabilized fibronectin domain compositions, methods and uses
|
|
CN103298489A
(zh)
|
2010-10-29 |
2013-09-11 |
伊缪诺金公司 |
新型egfr结合分子及其免疫偶联物
|
|
CN105399831A
(zh)
|
2010-10-29 |
2016-03-16 |
伊缪诺金公司 |
非拮抗性egfr结合分子及其免疫偶联物
|
|
RS58367B1
(sr)
*
|
2011-03-29 |
2019-03-29 |
Immunogen Inc |
Priprema konjugata antitela i majtanzinoida jednostepenim postupkom
|
|
IL281714B2
(en)
|
2011-04-01 |
2023-11-01 |
Immunogen Inc |
Methods for increasing the effectiveness of FOLR1 cancer therapy
|
|
CN103648532A
(zh)
*
|
2011-06-21 |
2014-03-19 |
伊缪诺金公司 |
具有肽连接子的新型美登木素生物碱衍生物及其偶联物
|
|
NL2009825C2
(en)
|
2012-11-16 |
2014-05-21 |
Ipee Bvba |
Sanitary appliance and method of determining use thereof.
|
|
CN104688740A
(zh)
*
|
2012-12-21 |
2015-06-10 |
百奥泰生物科技(广州)有限公司 |
类美登素衍生物及其制备方法和用途
|
|
KR102447350B1
(ko)
*
|
2013-02-08 |
2022-09-23 |
노파르티스 아게 |
면역접합체의 제조를 위한 항체의 변형에 사용되는 특정 부위
|
|
WO2014134486A2
(en)
*
|
2013-02-28 |
2014-09-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2014176284A1
(en)
*
|
2013-04-22 |
2014-10-30 |
Avelas Biosciences, Inc. |
Selective drug delivery compositions and methods of use
|
|
WO2014194030A2
(en)
*
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2015038426A1
(en)
*
|
2013-09-13 |
2015-03-19 |
Asana Biosciences, Llc |
Self-immolative linkers containing mandelic acid derivatives, drug-ligand conjugates for targeted therapies and uses thereof
|
|
JP6701077B2
(ja)
|
2013-12-19 |
2020-05-27 |
シアトル ジェネティックス， インコーポレイテッド |
標的化薬物結合体と使用するためのメチレンカルバメートリンカー
|
|
WO2015187428A1
(en)
*
|
2014-06-06 |
2015-12-10 |
Redwood Bioscience, Inc. |
Anti-her2 antibody-maytansine conjugates and methods of use thereof
|
|
TW201609152A
(zh)
*
|
2014-09-03 |
2016-03-16 |
免疫原公司 |
包含細胞結合劑及細胞毒性劑之偶聯物
|
|
EA201791203A1
(ru)
|
2014-12-08 |
2018-04-30 |
Сорренто Терапьютикс, Инк. |
ЛЕКАРСТВЕННЫЙ КОНЪЮГАТ АНТИТЕЛА ПРОТИВ с-МЕТ
|
|
ES2887273T3
(es)
|
2015-06-29 |
2021-12-22 |
Immunogen Inc |
Anticuerpos anti-CD123 y conjugados y derivados de los mismos
|
|
KR20250171447A
(ko)
|
2017-02-28 |
2025-12-08 |
이뮤노젠 아이엔씨 |
자기희생적 펩티드 링커 및 이들의 접합체를 갖는 메이탄시노이드 유도체
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|