JP2020510042A5 - - Google Patents
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- JP2020510042A5 JP2020510042A5 JP2019549396A JP2019549396A JP2020510042A5 JP 2020510042 A5 JP2020510042 A5 JP 2020510042A5 JP 2019549396 A JP2019549396 A JP 2019549396A JP 2019549396 A JP2019549396 A JP 2019549396A JP 2020510042 A5 JP2020510042 A5 JP 2020510042A5
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- 206010040914 Skin reaction Diseases 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 9
- 230000035483 skin reaction Effects 0.000 claims description 9
- 231100000430 skin reaction Toxicity 0.000 claims description 9
- 238000011282 treatment Methods 0.000 claims description 7
- 206010003051 Application site pain Diseases 0.000 claims description 6
- 206010040844 Skin exfoliation Diseases 0.000 claims description 6
- 230000002411 adverse Effects 0.000 claims description 6
- 230000008961 swelling Effects 0.000 claims description 4
- 206010049041 Application site infection Diseases 0.000 claims description 3
- 206010003046 Application site irritation Diseases 0.000 claims description 3
- 206010003053 Application site pruritus Diseases 0.000 claims description 3
- 206010053424 Application site swelling Diseases 0.000 claims description 3
- 206010015150 Erythema Diseases 0.000 claims description 3
- 206010019233 Headaches Diseases 0.000 claims description 3
- 206010068319 Oropharyngeal pain Diseases 0.000 claims description 3
- 206010034545 Periorbital oedema Diseases 0.000 claims description 3
- 201000007100 Pharyngitis Diseases 0.000 claims description 3
- 206010037888 Rash pustular Diseases 0.000 claims description 3
- 206010042674 Swelling Diseases 0.000 claims description 3
- 208000025865 Ulcer Diseases 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 230000035618 desquamation Effects 0.000 claims description 3
- 210000005069 ears Anatomy 0.000 claims description 3
- 230000003628 erosive effect Effects 0.000 claims description 3
- 238000004299 exfoliation Methods 0.000 claims description 3
- 210000000744 eyelid Anatomy 0.000 claims description 3
- 210000000245 forearm Anatomy 0.000 claims description 3
- 210000001061 forehead Anatomy 0.000 claims description 3
- 231100000869 headache Toxicity 0.000 claims description 3
- 208000000069 hyperpigmentation Diseases 0.000 claims description 3
- 230000003810 hyperpigmentation Effects 0.000 claims description 3
- 201000009240 nasopharyngitis Diseases 0.000 claims description 3
- 208000029561 pustule Diseases 0.000 claims description 3
- 210000004761 scalp Anatomy 0.000 claims description 3
- 230000035807 sensation Effects 0.000 claims description 3
- 230000036269 ulceration Effects 0.000 claims description 3
- 230000007332 vesicle formation Effects 0.000 claims description 3
- 239000003814 drug Substances 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 10
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 208000003367 Hypopigmentation Diseases 0.000 claims 1
- 208000009621 actinic keratosis Diseases 0.000 claims 1
- 230000003425 hypopigmentation Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 40
- 206010015967 Eye swelling Diseases 0.000 description 2
- 208000012641 Pigmentation disease Diseases 0.000 description 2
- 230000019612 pigmentation Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022180723A JP2023015269A (ja) | 2017-03-10 | 2022-11-11 | 光線角化症を治療および／または予防する方法 |
| JP2024207319A JP2025029010A (ja) | 2017-03-10 | 2024-11-28 | 光線角化症を治療および／または予防する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762469889P | 2017-03-10 | 2017-03-10 | |
| US62/469,889 | 2017-03-10 | ||
| PCT/US2018/021929 WO2018165647A1 (en) | 2017-03-10 | 2018-03-12 | Methods of treating and/or preventing actinic keratosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022180723A Division JP2023015269A (ja) | 2017-03-10 | 2022-11-11 | 光線角化症を治療および／または予防する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510042A JP2020510042A (ja) | 2020-04-02 |
| JP2020510042A5 true JP2020510042A5 (https=) | 2021-04-08 |
| JP7502863B2 JP7502863B2 (ja) | 2024-06-19 |
Family
ID=63446658
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019549396A Active JP7502863B2 (ja) | 2017-03-10 | 2018-03-12 | 光線角化症を治療および／または予防する方法 |
| JP2022180723A Pending JP2023015269A (ja) | 2017-03-10 | 2022-11-11 | 光線角化症を治療および／または予防する方法 |
| JP2024207319A Pending JP2025029010A (ja) | 2017-03-10 | 2024-11-28 | 光線角化症を治療および／または予防する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022180723A Pending JP2023015269A (ja) | 2017-03-10 | 2022-11-11 | 光線角化症を治療および／または予防する方法 |
| JP2024207319A Pending JP2025029010A (ja) | 2017-03-10 | 2024-11-28 | 光線角化症を治療および／または予防する方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10617693B2 (https=) |
| EP (2) | EP3592355B1 (https=) |
| JP (3) | JP7502863B2 (https=) |
| KR (2) | KR20240090837A (https=) |
| CN (1) | CN110891575A (https=) |
| AU (2) | AU2018231144B2 (https=) |
| BR (1) | BR112019018687A2 (https=) |
| CA (1) | CA3055938A1 (https=) |
| DK (1) | DK3592355T3 (https=) |
| ES (1) | ES3060528T3 (https=) |
| FI (1) | FI3592355T3 (https=) |
| HR (1) | HRP20260155T1 (https=) |
| IL (1) | IL269182B2 (https=) |
| LT (1) | LT3592355T (https=) |
| MX (2) | MX387658B (https=) |
| NZ (1) | NZ757105A (https=) |
| PL (1) | PL3592355T3 (https=) |
| PT (1) | PT3592355T (https=) |
| RS (1) | RS67713B1 (https=) |
| TW (1) | TWI841523B (https=) |
| WO (1) | WO2018165647A1 (https=) |
| ZA (1) | ZA202100106B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7968574B2 (en) * | 2004-12-28 | 2011-06-28 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| WO2018165647A1 (en) * | 2017-03-10 | 2018-09-13 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
| IL326637A (en) | 2017-09-07 | 2026-04-01 | Atnx Spv Llc | Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide |
| US11752156B2 (en) * | 2018-03-07 | 2023-09-12 | Athenex HK Innovative Limited | Compositions and methods for treating hyperproliferative skin disorders |
| WO2019188918A1 (ja) * | 2018-03-28 | 2019-10-03 | テルモ株式会社 | 医療デバイスおよび処置用法 |
| US20220305021A1 (en) * | 2019-06-05 | 2022-09-29 | Athenex, Inc. | Methods of treating and/or preventing psoriasis |
| CA3205857A1 (en) * | 2021-01-21 | 2022-07-28 | Michael MOLYNEAUX | Compositions and methods for treatment of skin cancers |
| CN120152984A (zh) * | 2023-10-13 | 2025-06-13 | 恩康药业科技（广州）有限公司 | 治疗和/或预防日光性角化病的化合物及方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0519424B8 (pt) | 2004-12-28 | 2021-05-25 | Athenex Inc | compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana |
| US7968574B2 (en) | 2004-12-28 | 2011-06-28 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| EP2041071B1 (en) | 2006-06-29 | 2014-06-18 | Kinex Pharmaceuticals, LLC | Biaryl compositions and methods for modulating a kinase cascade |
| US7538252B2 (en) | 2006-09-05 | 2009-05-26 | Bipar Sciences, Inc. | Drug design for tubulin inhibitors, compositions, and methods of treatment thereof |
| US7939529B2 (en) | 2007-05-17 | 2011-05-10 | Kinex Pharmaceuticals, Llc | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof |
| TWI457336B (zh) | 2006-12-28 | 2014-10-21 | Kinex Pharmaceuticals Llc | 調節激酶級聯之組成物及方法 |
| US7935697B2 (en) | 2006-12-28 | 2011-05-03 | Kinex Pharmaceuticals, Llc | Compositions for modulating a kinase cascade and methods of use thereof |
| EP2155681B1 (en) | 2007-05-17 | 2018-05-02 | Athenex, Inc. | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof |
| EP2143421A1 (en) | 2008-07-07 | 2010-01-13 | Almirall Hermal GmbH | Topical composition for the treatment of actinic keratosis |
| WO2010080345A1 (en) * | 2008-12-19 | 2010-07-15 | Graceway Pharmaceuticals, Llc | Lower dosage strength imiquimod formulations and short dosing regimens for treating actinic keratosis |
| US8741857B1 (en) * | 2012-01-30 | 2014-06-03 | Lawrence Moy | Treatments for actinic keratoses |
| NZ606177A (en) * | 2012-01-30 | 2014-03-28 | Dolorgiet Gmbh & Co Kg | Compositions for the treatment of actinic keratosis |
| JP6280546B2 (ja) | 2012-06-26 | 2018-02-14 | デル マー ファーマシューティカルズ | ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 |
| WO2018165647A1 (en) * | 2017-03-10 | 2018-09-13 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
-
2018
- 2018-03-12 WO PCT/US2018/021929 patent/WO2018165647A1/en not_active Ceased
- 2018-03-12 PL PL18764980.1T patent/PL3592355T3/pl unknown
- 2018-03-12 LT LTEPPCT/US2018/021929T patent/LT3592355T/lt unknown
- 2018-03-12 EP EP18764980.1A patent/EP3592355B1/en active Active
- 2018-03-12 JP JP2019549396A patent/JP7502863B2/ja active Active
- 2018-03-12 MX MX2019010707A patent/MX387658B/es unknown
- 2018-03-12 FI FIEP18764980.1T patent/FI3592355T3/fi active
- 2018-03-12 CN CN201880029861.9A patent/CN110891575A/zh active Pending
- 2018-03-12 HR HRP20260155TT patent/HRP20260155T1/hr unknown
- 2018-03-12 NZ NZ757105A patent/NZ757105A/en unknown
- 2018-03-12 PT PT187649801T patent/PT3592355T/pt unknown
- 2018-03-12 IL IL269182A patent/IL269182B2/en unknown
- 2018-03-12 EP EP25210508.5A patent/EP4659740A3/en active Pending
- 2018-03-12 KR KR1020247017149A patent/KR20240090837A/ko active Pending
- 2018-03-12 DK DK18764980.1T patent/DK3592355T3/da active
- 2018-03-12 RS RS20260134A patent/RS67713B1/sr unknown
- 2018-03-12 ES ES18764980T patent/ES3060528T3/es active Active
- 2018-03-12 US US15/918,100 patent/US10617693B2/en active Active
- 2018-03-12 TW TW107108242A patent/TWI841523B/zh active
- 2018-03-12 AU AU2018231144A patent/AU2018231144B2/en active Active
- 2018-03-12 BR BR112019018687-5A patent/BR112019018687A2/pt not_active Application Discontinuation
- 2018-03-12 KR KR1020197029678A patent/KR20190141661A/ko not_active Ceased
- 2018-03-12 CA CA3055938A patent/CA3055938A1/en active Pending
-
2019
- 2019-09-09 MX MX2021013354A patent/MX2021013354A/es unknown
-
2020
- 2020-02-28 US US16/804,092 patent/US11497750B2/en active Active
-
2021
- 2021-01-07 ZA ZA2021/00106A patent/ZA202100106B/en unknown
-
2022
- 2022-10-11 US US17/963,502 patent/US20230172942A1/en active Pending
- 2022-11-11 JP JP2022180723A patent/JP2023015269A/ja active Pending
-
2024
- 2024-03-20 AU AU2024201828A patent/AU2024201828B2/en active Active
- 2024-11-28 JP JP2024207319A patent/JP2025029010A/ja active Pending
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