AU2018231144B2 - Methods of treating and/or preventing actinic keratosis - Google Patents
Methods of treating and/or preventing actinic keratosis Download PDFInfo
- Publication number
- AU2018231144B2 AU2018231144B2 AU2018231144A AU2018231144A AU2018231144B2 AU 2018231144 B2 AU2018231144 B2 AU 2018231144B2 AU 2018231144 A AU2018231144 A AU 2018231144A AU 2018231144 A AU2018231144 A AU 2018231144A AU 2018231144 B2 AU2018231144 B2 AU 2018231144B2
- Authority
- AU
- Australia
- Prior art keywords
- subject
- affected area
- days
- day
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2024201828A AU2024201828B2 (en) | 2017-03-10 | 2024-03-20 | Methods of treating and/or preventing actinic keratosis |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762469889P | 2017-03-10 | 2017-03-10 | |
| US62/469,889 | 2017-03-10 | ||
| PCT/US2018/021929 WO2018165647A1 (en) | 2017-03-10 | 2018-03-12 | Methods of treating and/or preventing actinic keratosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2024201828A Division AU2024201828B2 (en) | 2017-03-10 | 2024-03-20 | Methods of treating and/or preventing actinic keratosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2018231144A1 AU2018231144A1 (en) | 2019-10-03 |
| AU2018231144B2 true AU2018231144B2 (en) | 2023-12-21 |
Family
ID=63446658
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018231144A Active AU2018231144B2 (en) | 2017-03-10 | 2018-03-12 | Methods of treating and/or preventing actinic keratosis |
| AU2024201828A Active AU2024201828B2 (en) | 2017-03-10 | 2024-03-20 | Methods of treating and/or preventing actinic keratosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2024201828A Active AU2024201828B2 (en) | 2017-03-10 | 2024-03-20 | Methods of treating and/or preventing actinic keratosis |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10617693B2 (https=) |
| EP (2) | EP3592355B1 (https=) |
| JP (3) | JP7502863B2 (https=) |
| KR (2) | KR20240090837A (https=) |
| CN (1) | CN110891575A (https=) |
| AU (2) | AU2018231144B2 (https=) |
| BR (1) | BR112019018687A2 (https=) |
| CA (1) | CA3055938A1 (https=) |
| DK (1) | DK3592355T3 (https=) |
| ES (1) | ES3060528T3 (https=) |
| FI (1) | FI3592355T3 (https=) |
| HR (1) | HRP20260155T1 (https=) |
| IL (1) | IL269182B2 (https=) |
| LT (1) | LT3592355T (https=) |
| MX (2) | MX387658B (https=) |
| NZ (1) | NZ757105A (https=) |
| PL (1) | PL3592355T3 (https=) |
| PT (1) | PT3592355T (https=) |
| RS (1) | RS67713B1 (https=) |
| TW (1) | TWI841523B (https=) |
| WO (1) | WO2018165647A1 (https=) |
| ZA (1) | ZA202100106B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7968574B2 (en) * | 2004-12-28 | 2011-06-28 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| WO2018165647A1 (en) * | 2017-03-10 | 2018-09-13 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
| IL326637A (en) | 2017-09-07 | 2026-04-01 | Atnx Spv Llc | Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide |
| US11752156B2 (en) * | 2018-03-07 | 2023-09-12 | Athenex HK Innovative Limited | Compositions and methods for treating hyperproliferative skin disorders |
| WO2019188918A1 (ja) * | 2018-03-28 | 2019-10-03 | テルモ株式会社 | 医療デバイスおよび処置用法 |
| US20220305021A1 (en) * | 2019-06-05 | 2022-09-29 | Athenex, Inc. | Methods of treating and/or preventing psoriasis |
| CA3205857A1 (en) * | 2021-01-21 | 2022-07-28 | Michael MOLYNEAUX | Compositions and methods for treatment of skin cancers |
| CN120152984A (zh) * | 2023-10-13 | 2025-06-13 | 恩康药业科技（广州）有限公司 | 治疗和/或预防日光性角化病的化合物及方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0519424B8 (pt) | 2004-12-28 | 2021-05-25 | Athenex Inc | compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana |
| US7968574B2 (en) | 2004-12-28 | 2011-06-28 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| EP2041071B1 (en) | 2006-06-29 | 2014-06-18 | Kinex Pharmaceuticals, LLC | Biaryl compositions and methods for modulating a kinase cascade |
| US7538252B2 (en) | 2006-09-05 | 2009-05-26 | Bipar Sciences, Inc. | Drug design for tubulin inhibitors, compositions, and methods of treatment thereof |
| US7939529B2 (en) | 2007-05-17 | 2011-05-10 | Kinex Pharmaceuticals, Llc | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof |
| TWI457336B (zh) | 2006-12-28 | 2014-10-21 | Kinex Pharmaceuticals Llc | 調節激酶級聯之組成物及方法 |
| US7935697B2 (en) | 2006-12-28 | 2011-05-03 | Kinex Pharmaceuticals, Llc | Compositions for modulating a kinase cascade and methods of use thereof |
| EP2155681B1 (en) | 2007-05-17 | 2018-05-02 | Athenex, Inc. | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof |
| EP2143421A1 (en) | 2008-07-07 | 2010-01-13 | Almirall Hermal GmbH | Topical composition for the treatment of actinic keratosis |
| WO2010080345A1 (en) * | 2008-12-19 | 2010-07-15 | Graceway Pharmaceuticals, Llc | Lower dosage strength imiquimod formulations and short dosing regimens for treating actinic keratosis |
| US8741857B1 (en) * | 2012-01-30 | 2014-06-03 | Lawrence Moy | Treatments for actinic keratoses |
| NZ606177A (en) * | 2012-01-30 | 2014-03-28 | Dolorgiet Gmbh & Co Kg | Compositions for the treatment of actinic keratosis |
| JP6280546B2 (ja) | 2012-06-26 | 2018-02-14 | デル マー ファーマシューティカルズ | ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 |
| WO2018165647A1 (en) * | 2017-03-10 | 2018-09-13 | Athenex, Inc. | Methods of treating and/or preventing actinic keratosis |
-
2018
- 2018-03-12 WO PCT/US2018/021929 patent/WO2018165647A1/en not_active Ceased
- 2018-03-12 PL PL18764980.1T patent/PL3592355T3/pl unknown
- 2018-03-12 LT LTEPPCT/US2018/021929T patent/LT3592355T/lt unknown
- 2018-03-12 EP EP18764980.1A patent/EP3592355B1/en active Active
- 2018-03-12 JP JP2019549396A patent/JP7502863B2/ja active Active
- 2018-03-12 MX MX2019010707A patent/MX387658B/es unknown
- 2018-03-12 FI FIEP18764980.1T patent/FI3592355T3/fi active
- 2018-03-12 CN CN201880029861.9A patent/CN110891575A/zh active Pending
- 2018-03-12 HR HRP20260155TT patent/HRP20260155T1/hr unknown
- 2018-03-12 NZ NZ757105A patent/NZ757105A/en unknown
- 2018-03-12 PT PT187649801T patent/PT3592355T/pt unknown
- 2018-03-12 IL IL269182A patent/IL269182B2/en unknown
- 2018-03-12 EP EP25210508.5A patent/EP4659740A3/en active Pending
- 2018-03-12 KR KR1020247017149A patent/KR20240090837A/ko active Pending
- 2018-03-12 DK DK18764980.1T patent/DK3592355T3/da active
- 2018-03-12 RS RS20260134A patent/RS67713B1/sr unknown
- 2018-03-12 ES ES18764980T patent/ES3060528T3/es active Active
- 2018-03-12 US US15/918,100 patent/US10617693B2/en active Active
- 2018-03-12 TW TW107108242A patent/TWI841523B/zh active
- 2018-03-12 AU AU2018231144A patent/AU2018231144B2/en active Active
- 2018-03-12 BR BR112019018687-5A patent/BR112019018687A2/pt not_active Application Discontinuation
- 2018-03-12 KR KR1020197029678A patent/KR20190141661A/ko not_active Ceased
- 2018-03-12 CA CA3055938A patent/CA3055938A1/en active Pending
-
2019
- 2019-09-09 MX MX2021013354A patent/MX2021013354A/es unknown
-
2020
- 2020-02-28 US US16/804,092 patent/US11497750B2/en active Active
-
2021
- 2021-01-07 ZA ZA2021/00106A patent/ZA202100106B/en unknown
-
2022
- 2022-10-11 US US17/963,502 patent/US20230172942A1/en active Pending
- 2022-11-11 JP JP2022180723A patent/JP2023015269A/ja active Pending
-
2024
- 2024-03-20 AU AU2024201828A patent/AU2024201828B2/en active Active
- 2024-11-28 JP JP2024207319A patent/JP2025029010A/ja active Pending
Non-Patent Citations (3)
| Title |
|---|
| "NCT02337205", CLINICALTRIALS.GOV, JPN6021045855, 2016, pages 1 - 4, ISSN: 0004643522 * |
| "NCT02838628", CLINICALTRIALS.GOV, JPN6021045856, 2016, pages 1 - 5, ISSN: 0004643523 * |
| KINEX PHARMACEUTICALS: "Kinex Pharmaceuticals Announces Allowance of the Investigational New Drug (IND) application for KX2-391 Ointment by the United States Food and Drug Administration. * |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: ATNX SPV, LLC Free format text: FORMER APPLICANT(S): ATHENEX, INC. |
|
| FGA | Letters patent sealed or granted (standard patent) |