CN110891575A - 治疗和/或预防光化性角化病的方法 - Google Patents

治疗和/或预防光化性角化病的方法 Download PDF

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Publication number
CN110891575A
CN110891575A CN201880029861.9A CN201880029861A CN110891575A CN 110891575 A CN110891575 A CN 110891575A CN 201880029861 A CN201880029861 A CN 201880029861A CN 110891575 A CN110891575 A CN 110891575A
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China
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CN201880029861.9A
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English (en)
Chinese (zh)
Inventor
M-F.R.关
J.Y-N.刘
E.D.克莱默
D.L.卡特勒
J.方
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Anzix Special Purpose Co ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=63446658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN110891575(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
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Publication of CN110891575A publication Critical patent/CN110891575A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
CN201880029861.9A 2017-03-10 2018-03-12 治疗和/或预防光化性角化病的方法 Pending CN110891575A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762469889P 2017-03-10 2017-03-10
US62/469,889 2017-03-10
PCT/US2018/021929 WO2018165647A1 (en) 2017-03-10 2018-03-12 Methods of treating and/or preventing actinic keratosis

Publications (1)

Publication Number Publication Date
CN110891575A true CN110891575A (zh) 2020-03-17

Family

ID=63446658

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Application Number Title Priority Date Filing Date
CN201880029861.9A Pending CN110891575A (zh) 2017-03-10 2018-03-12 治疗和/或预防光化性角化病的方法

Country Status (22)

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US (3) US10617693B2 (https=)
EP (2) EP3592355B1 (https=)
JP (3) JP7502863B2 (https=)
KR (2) KR20240090837A (https=)
CN (1) CN110891575A (https=)
AU (2) AU2018231144B2 (https=)
BR (1) BR112019018687A2 (https=)
CA (1) CA3055938A1 (https=)
DK (1) DK3592355T3 (https=)
ES (1) ES3060528T3 (https=)
FI (1) FI3592355T3 (https=)
HR (1) HRP20260155T1 (https=)
IL (1) IL269182B2 (https=)
LT (1) LT3592355T (https=)
MX (2) MX387658B (https=)
NZ (1) NZ757105A (https=)
PL (1) PL3592355T3 (https=)
PT (1) PT3592355T (https=)
RS (1) RS67713B1 (https=)
TW (1) TWI841523B (https=)
WO (1) WO2018165647A1 (https=)
ZA (1) ZA202100106B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025077886A1 (zh) * 2023-10-13 2025-04-17 恩康药业科技(广州)有限公司 治疗和/或预防日光性角化病的化合物及方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7968574B2 (en) * 2004-12-28 2011-06-28 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
WO2018165647A1 (en) * 2017-03-10 2018-09-13 Athenex, Inc. Methods of treating and/or preventing actinic keratosis
IL326637A (en) 2017-09-07 2026-04-01 Atnx Spv Llc Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide
US11752156B2 (en) * 2018-03-07 2023-09-12 Athenex HK Innovative Limited Compositions and methods for treating hyperproliferative skin disorders
WO2019188918A1 (ja) * 2018-03-28 2019-10-03 テルモ株式会社 医療デバイスおよび処置用法
US20220305021A1 (en) * 2019-06-05 2022-09-29 Athenex, Inc. Methods of treating and/or preventing psoriasis
CA3205857A1 (en) * 2021-01-21 2022-07-28 Michael MOLYNEAUX Compositions and methods for treatment of skin cancers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110021555A1 (en) * 2008-12-19 2011-01-27 Graceway Pharmaceuticals, Llc Lower dosage strength imiquimod formulations and shorter dosing regimens for treating actinic keratoses

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0519424B8 (pt) 2004-12-28 2021-05-25 Athenex Inc compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana
US7968574B2 (en) 2004-12-28 2011-06-28 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
EP2041071B1 (en) 2006-06-29 2014-06-18 Kinex Pharmaceuticals, LLC Biaryl compositions and methods for modulating a kinase cascade
US7538252B2 (en) 2006-09-05 2009-05-26 Bipar Sciences, Inc. Drug design for tubulin inhibitors, compositions, and methods of treatment thereof
US7939529B2 (en) 2007-05-17 2011-05-10 Kinex Pharmaceuticals, Llc Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
TWI457336B (zh) 2006-12-28 2014-10-21 Kinex Pharmaceuticals Llc 調節激酶級聯之組成物及方法
US7935697B2 (en) 2006-12-28 2011-05-03 Kinex Pharmaceuticals, Llc Compositions for modulating a kinase cascade and methods of use thereof
EP2155681B1 (en) 2007-05-17 2018-05-02 Athenex, Inc. Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
EP2143421A1 (en) 2008-07-07 2010-01-13 Almirall Hermal GmbH Topical composition for the treatment of actinic keratosis
US8741857B1 (en) * 2012-01-30 2014-06-03 Lawrence Moy Treatments for actinic keratoses
NZ606177A (en) * 2012-01-30 2014-03-28 Dolorgiet Gmbh & Co Kg Compositions for the treatment of actinic keratosis
JP6280546B2 (ja) 2012-06-26 2018-02-14 デル マー ファーマシューティカルズ ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
WO2018165647A1 (en) * 2017-03-10 2018-09-13 Athenex, Inc. Methods of treating and/or preventing actinic keratosis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110021555A1 (en) * 2008-12-19 2011-01-27 Graceway Pharmaceuticals, Llc Lower dosage strength imiquimod formulations and shorter dosing regimens for treating actinic keratoses

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KINEX PHARMACEUTICALS: "Kinex Pharmaceuticals Announces Allowance of the Investigational New Drug (IND) application for KX2-391 Ointment by the United States Food and Drug Administration (FDA)", 《HTTPS://WWW.PRNEWSWIRE.COM/NEWS- RELEASES/KINEX-PHARMACEUTICALS-ANNOUNCES-ALLOWANCE-OF-THE-INVESTIGATIONAL-NEW-DRUG-IND-APPLICATION-FOR-KX2-391-OINTMENT-BY-THE-UNITED-STATES-FOOD-AND-DRUG-ADMINISTRATION-FDA-268466522.HTML》 *
赵文丽: "FDA 接受 KX2-391 软膏治疗光化性角化病的研究性新药申请", 《国际药学研究杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025077886A1 (zh) * 2023-10-13 2025-04-17 恩康药业科技(广州)有限公司 治疗和/或预防日光性角化病的化合物及方法

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Publication number Publication date
AU2018231144A1 (en) 2019-10-03
US10617693B2 (en) 2020-04-14
MX387658B (es) 2025-03-18
LT3592355T (lt) 2026-02-25
US20230172942A1 (en) 2023-06-08
ES3060528T3 (en) 2026-03-26
JP2020510042A (ja) 2020-04-02
RS67713B1 (sr) 2026-02-27
NZ757105A (en) 2026-02-27
RU2019131757A (ru) 2021-04-12
JP2023015269A (ja) 2023-01-31
AU2018231144B2 (en) 2023-12-21
TW201842913A (zh) 2018-12-16
IL269182B1 (en) 2023-07-01
WO2018165647A1 (en) 2018-09-13
JP7502863B2 (ja) 2024-06-19
FI3592355T3 (fi) 2026-02-13
PT3592355T (pt) 2026-02-03
EP4659740A2 (en) 2025-12-10
EP3592355A4 (en) 2021-01-06
CA3055938A1 (en) 2018-09-13
MX2021013354A (es) 2021-11-18
US20200197405A1 (en) 2020-06-25
AU2024201828B2 (en) 2026-02-19
EP3592355A1 (en) 2020-01-15
TWI841523B (zh) 2024-05-11
PL3592355T3 (pl) 2026-04-07
KR20240090837A (ko) 2024-06-21
AU2024201828A1 (en) 2024-05-02
DK3592355T3 (da) 2026-02-16
EP3592355B1 (en) 2025-12-10
HRP20260155T1 (hr) 2026-03-27
MX2019010707A (es) 2020-01-15
KR20190141661A (ko) 2019-12-24
IL269182B2 (en) 2023-11-01
RU2019131757A3 (https=) 2021-05-31
BR112019018687A2 (pt) 2020-04-07
US20180256589A1 (en) 2018-09-13
US11497750B2 (en) 2022-11-15
ZA202100106B (en) 2022-08-31
JP2025029010A (ja) 2025-03-05
EP4659740A3 (en) 2026-02-18
IL269182A (en) 2019-11-28

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CB03 Change of inventor or designer information
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Inventor after: Guan Mianfen

Inventor after: Liu Yaonan

Inventor after: E. D. Kramer

Inventor after: D.L. Cutler

Inventor after: Fang Rongsheng

Inventor before: M-F.R.Guan

Inventor before: J.Y-N.Liu

Inventor before: E. D. Kramer

Inventor before: D.L. Cutler

Inventor before: J.Fang

TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20230413

Address after: New York, United States

Applicant after: Anzix Special Purpose Co.,Ltd.

Address before: New York, United States

Applicant before: Abbott