JP2020509767A5 - - Google Patents
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- JP2020509767A5 JP2020509767A5 JP2019550622A JP2019550622A JP2020509767A5 JP 2020509767 A5 JP2020509767 A5 JP 2020509767A5 JP 2019550622 A JP2019550622 A JP 2019550622A JP 2019550622 A JP2019550622 A JP 2019550622A JP 2020509767 A5 JP2020509767 A5 JP 2020509767A5
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- JP
- Japan
- Prior art keywords
- seq
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- amino acid
- cdr2
- cdr1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762471956P | 2017-03-15 | 2017-03-15 | |
| US62/471,956 | 2017-03-15 | ||
| PCT/US2018/022759 WO2018170338A2 (en) | 2017-03-15 | 2018-03-15 | High affinity mage-a1-specific tcrs and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021039957A Division JP2021090462A (ja) | 2017-03-15 | 2021-03-12 | 高親和性ｍａｇｅ−ａ１特異的ｔｃｒ及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020509767A JP2020509767A (ja) | 2020-04-02 |
| JP2020509767A5 true JP2020509767A5 (enExample) | 2021-04-22 |
| JP7037577B2 JP7037577B2 (ja) | 2022-03-16 |
Family
ID=63523985
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550622A Expired - Fee Related JP7037577B2 (ja) | 2017-03-15 | 2018-03-15 | 高親和性ｍａｇｅ－ａ１特異的ｔｃｒ及びその使用 |
| JP2021039957A Pending JP2021090462A (ja) | 2017-03-15 | 2021-03-12 | 高親和性ｍａｇｅ−ａ１特異的ｔｃｒ及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021039957A Pending JP2021090462A (ja) | 2017-03-15 | 2021-03-12 | 高親和性ｍａｇｅ−ａ１特異的ｔｃｒ及びその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11034748B2 (enExample) |
| EP (1) | EP3595708A4 (enExample) |
| JP (2) | JP7037577B2 (enExample) |
| KR (1) | KR102375033B1 (enExample) |
| CN (1) | CN110582299A (enExample) |
| AU (1) | AU2018234830B2 (enExample) |
| BR (1) | BR112019018863A8 (enExample) |
| CA (1) | CA3055983A1 (enExample) |
| EA (1) | EA201992131A1 (enExample) |
| IL (1) | IL269250A (enExample) |
| MX (1) | MX2019010972A (enExample) |
| SG (1) | SG11201908527SA (enExample) |
| WO (1) | WO2018170338A2 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2018138838A (ru) | 2016-04-08 | 2020-05-14 | Адаптимьюн Лимитед | Т-клеточные рецепторы |
| KR102375218B1 (ko) | 2016-12-08 | 2022-03-17 | 이매틱스 바이오테크놀로지스 게엠베하 | T 세포 수용체 및 이를 사용하는 면역 요법 |
| DE102016123847B3 (de) * | 2016-12-08 | 2018-04-05 | Immatics Biotechnologies Gmbh | Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie |
| CA3055983A1 (en) * | 2017-03-15 | 2018-09-20 | Fred Hutchinson Cancer Research Center | High affinity mage-a1-specific tcrs and uses thereof |
| AU2019256536B2 (en) | 2018-04-19 | 2025-09-18 | Baylor College Of Medicine | Reprogramming CD4 T cells into cytotoxic CD8 cells by forced expression of CD8αβ and Class 1 restricted T cell receptors |
| GB201819540D0 (en) * | 2018-11-30 | 2019-01-16 | Adaptimmune Ltd | T cell modification |
| TWI850360B (zh) * | 2019-04-04 | 2024-08-01 | 德商梅迪基因免疫治療公司 | 黑色素瘤相關抗原１（ｍａｇｅａ１）特異性ｔ細胞受體及其用途 |
| SG11202111865UA (en) * | 2019-05-01 | 2021-11-29 | Pact Pharma Inc | Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy |
| WO2020263830A1 (en) | 2019-06-25 | 2020-12-30 | Gilead Sciences, Inc. | Flt3l-fc fusion proteins and methods of use |
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| BR112022014623A2 (pt) | 2020-02-14 | 2022-09-13 | Jounce Therapeutics Inc | Anticorpos e proteínas de fusão que se ligam a ccr8 e usos dos mesmos |
| CN111320703A (zh) * | 2020-03-11 | 2020-06-23 | 北京双赢科创生物科技有限公司 | 靶向cd22的嵌合抗原受体及其应用 |
| CN111499763A (zh) * | 2020-03-31 | 2020-08-07 | 江苏省省级机关医院 | 一种靶向mage-a1的特异性全人源嵌合抗原受体及其应用 |
| AU2021270378A1 (en) * | 2020-05-13 | 2022-12-15 | Adaptimmune Limited | Method of treatment of cancer or tumour |
| CN112194719A (zh) * | 2020-09-01 | 2021-01-08 | 中日友好医院(中日友好临床医学研究所) | Crt抗原和mage-a1抗原的制备及其应用 |
| TW202222841A (zh) | 2020-10-06 | 2022-06-16 | 福瑞德哈金森腫瘤研究中心 | 用於治療表現mage-a1之疾病的組成物及方法 |
| TWI815194B (zh) | 2020-10-22 | 2023-09-11 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| WO2022132836A2 (en) | 2020-12-14 | 2022-06-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for cellular immunotherapy |
| US12234473B2 (en) | 2020-12-31 | 2025-02-25 | Immatics US, Inc. | CD8 polypeptides, compositions, and methods of using thereof |
| WO2022221478A1 (en) * | 2021-04-14 | 2022-10-20 | Tscan Therapeutics, Inc. | Binding proteins recognizing ha-2 antigen and uses thereof |
| US20220389394A1 (en) | 2021-05-18 | 2022-12-08 | Gilead Sciences, Inc. | METHODS OF USING FLT3L-Fc FUSION PROTEINS |
| JP2024539252A (ja) | 2021-10-28 | 2024-10-28 | ギリアード サイエンシーズ， インコーポレイテッド | ピリジジン－３（２ｈ）－オン誘導体 |
| PE20241186A1 (es) | 2021-10-29 | 2024-06-03 | Gilead Sciences Inc | Compuestos de cd73 |
| WO2023083864A1 (en) | 2021-11-09 | 2023-05-19 | T-Knife Gmbh | Methods of selecting a patient for treatment of a mage-a1 positive solid tumor, of predicting whether a patient being diagnosed with mage-a1 positive solid tumor will be responsive to treatment of this tumor and of treating a patient being diagnosed with such a mage-a1 positive solid tumor as well as corresponding pharmaceutical compositions and diagnostic kits |
| US12122764B2 (en) | 2021-12-22 | 2024-10-22 | Gilead Sciences, Inc. | IKAROS zinc finger family degraders and uses thereof |
| EP4452414A2 (en) | 2021-12-22 | 2024-10-30 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| CA3253296A1 (en) | 2022-03-17 | 2023-09-21 | Gilead Sciences Inc | Zinc Finger Degradation Agents of the Ikaros Family and Their Uses |
| CR20240451A (es) | 2022-04-21 | 2024-12-04 | Gilead Sciences Inc | Compuestos de modulación de kras g12d |
| CN116948011A (zh) * | 2022-04-27 | 2023-10-27 | 恒瑞源正(广州)生物科技有限公司 | Mage-a1特异性t细胞受体及其用途 |
| EP4534554A1 (en) * | 2022-06-01 | 2025-04-09 | Corregene Biotechnology Co., Ltd. | Mage-a1 specific tcr and use thereof |
| NL2032130B1 (en) * | 2022-06-10 | 2023-12-18 | Academisch Ziekenhuis Leiden | T cell receptors directed against melanoma-associated antigen and uses thereof |
| JP2025522762A (ja) | 2022-07-01 | 2025-07-17 | ギリアード サイエンシーズ， インコーポレイテッド | Ｃｄ７３化合物 |
| EP4638436A1 (en) | 2022-12-22 | 2025-10-29 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2024215754A1 (en) | 2023-04-11 | 2024-10-17 | Gilead Sciences, Inc. | Kras modulating compounds |
| AU2024259556A1 (en) | 2023-04-21 | 2025-10-23 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| US20250042922A1 (en) | 2023-06-30 | 2025-02-06 | Gilead Sciences, Inc. | Kras modulating compounds |
| US20250066328A1 (en) | 2023-07-26 | 2025-02-27 | Gilead Sciences, Inc. | Parp7 inhibitors |
| TW202519517A (zh) | 2023-07-26 | 2025-05-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| WO2025054530A1 (en) | 2023-09-08 | 2025-03-13 | Gilead Sciences, Inc. | Pyrimidine-containing polycyclic derivatives as kras g12d modulating compounds |
| WO2025054347A1 (en) | 2023-09-08 | 2025-03-13 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| WO2025081123A1 (en) | 2023-10-12 | 2025-04-17 | Fred Hutchinson Cancer Center | Methods and compositions for improving t cell immunotherapy |
| US20250154172A1 (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025146286A1 (en) * | 2024-01-04 | 2025-07-10 | Immunoscape Pte. Ltd. | Human t cell receptors and uses thereof |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| WO2025245169A1 (en) | 2024-05-21 | 2025-11-27 | Fred Hutchinson Cancer Center | Immunotherapy cells equipped with a collagen-targeting payload |
| US20250376484A1 (en) | 2024-05-21 | 2025-12-11 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
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| CN106188274A (zh) * | 2015-05-06 | 2016-12-07 | 广州市香雪制药股份有限公司 | 识别rhamm抗原短肽的t细胞受体 |
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| JO3620B1 (ar) | 2015-08-05 | 2020-08-27 | Amgen Res Munich Gmbh | مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم |
| CN105316362B (zh) * | 2015-08-19 | 2020-03-17 | 暨南大学 | 一种Dual-RMCE介导的TCR基因置换系统及其方法 |
| CN106749620B (zh) * | 2016-03-29 | 2020-09-25 | 广东香雪精准医疗技术有限公司 | 识别mage-a1抗原短肽的t细胞受体 |
| KR102436129B1 (ko) * | 2016-06-17 | 2022-08-26 | 메디진 이뮤노테라피스 게엠바하 | T 세포 수용체 및 이의 용도 |
| DE102016115246C5 (de) * | 2016-08-17 | 2018-12-20 | Immatics Biotechnologies Gmbh | Neue t-zellrezeptoren und deren verwendung in immuntherapie |
| DE102016123847B3 (de) * | 2016-12-08 | 2018-04-05 | Immatics Biotechnologies Gmbh | Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie |
| CA3055983A1 (en) * | 2017-03-15 | 2018-09-20 | Fred Hutchinson Cancer Research Center | High affinity mage-a1-specific tcrs and uses thereof |
-
2018
- 2018-03-15 CA CA3055983A patent/CA3055983A1/en active Pending
- 2018-03-15 KR KR1020197029977A patent/KR102375033B1/ko active Active
- 2018-03-15 MX MX2019010972A patent/MX2019010972A/es unknown
- 2018-03-15 WO PCT/US2018/022759 patent/WO2018170338A2/en not_active Ceased
- 2018-03-15 JP JP2019550622A patent/JP7037577B2/ja not_active Expired - Fee Related
- 2018-03-15 EA EA201992131A patent/EA201992131A1/ru unknown
- 2018-03-15 BR BR112019018863A patent/BR112019018863A8/pt not_active Application Discontinuation
- 2018-03-15 SG SG11201908527S patent/SG11201908527SA/en unknown
- 2018-03-15 AU AU2018234830A patent/AU2018234830B2/en not_active Withdrawn - After Issue
- 2018-03-15 CN CN201880026621.3A patent/CN110582299A/zh active Pending
- 2018-03-15 EP EP18767104.5A patent/EP3595708A4/en not_active Withdrawn
-
2019
- 2019-09-10 IL IL26925019A patent/IL269250A/en unknown
- 2019-09-13 US US16/571,013 patent/US11034748B2/en active Active
-
2020
- 2020-12-22 US US17/131,688 patent/US20210355189A1/en not_active Abandoned
-
2021
- 2021-03-12 JP JP2021039957A patent/JP2021090462A/ja active Pending
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