JP2020509755A5 - - Google Patents
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- JP2020509755A5 JP2020509755A5 JP2019548956A JP2019548956A JP2020509755A5 JP 2020509755 A5 JP2020509755 A5 JP 2020509755A5 JP 2019548956 A JP2019548956 A JP 2019548956A JP 2019548956 A JP2019548956 A JP 2019548956A JP 2020509755 A5 JP2020509755 A5 JP 2020509755A5
- Authority
- JP
- Japan
- Prior art keywords
- host cell
- recombinant
- recombinant host
- seq
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022034241A JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762470153P | 2017-03-10 | 2017-03-10 | |
| US62/470,153 | 2017-03-10 | ||
| PCT/US2018/021817 WO2018165594A1 (en) | 2017-03-10 | 2018-03-09 | Compositions and methods for producing high secreted yields of recombinant proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022034241A Division JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020509755A JP2020509755A (ja) | 2020-04-02 |
| JP2020509755A5 true JP2020509755A5 (https=) | 2021-04-15 |
| JP7063486B2 JP7063486B2 (ja) | 2022-05-09 |
Family
ID=63448314
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548956A Active JP7063486B2 (ja) | 2017-03-10 | 2018-03-09 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2022034241A Pending JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A Pending JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022034241A Pending JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A Pending JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US10906947B2 (https=) |
| EP (1) | EP3592762A4 (https=) |
| JP (3) | JP7063486B2 (https=) |
| KR (4) | KR20250121449A (https=) |
| WO (1) | WO2018165594A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11365225B2 (en) * | 2015-11-19 | 2022-06-21 | President And Fellows Of Harvard College | Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria |
| US12351805B2 (en) | 2015-11-19 | 2025-07-08 | Northeastern University | Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria |
| EP3592800A4 (en) | 2017-03-10 | 2021-01-06 | Bolt Threads, Inc. | COMPOSITIONS AND METHODS OF PRODUCING HIGHLY SECRETED YIELD OF RECOMBINANT PROTEIN |
| KR20250121449A (ko) | 2017-03-10 | 2025-08-12 | 볼트 쓰레즈, 인크. | 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법 |
| CA3155541A1 (en) * | 2019-11-27 | 2021-06-03 | Ravi Chandra BEERAM | Nucleic acids, vectors, host cells and methods for production of fructosyltransferase from aspergillus japonicus |
| IL304910A (en) | 2021-02-12 | 2023-10-01 | Boehringer Ingelheim Rcv Gmbh | Signal peptides for increased protein secretion |
| US11993068B2 (en) | 2022-04-15 | 2024-05-28 | Spora Cayman Holdings Limited | Mycotextiles including activated scaffolds and nano-particle cross-linkers and methods of making them |
| CN119630280A (zh) | 2022-05-14 | 2025-03-14 | 诺维信公司 | 用于预防、处理、抑制和/或消除植物病原性侵染和感染的组合物和方法 |
| WO2024141641A2 (en) | 2022-12-30 | 2024-07-04 | Biotalys NV | Secretion signals |
| US12467171B2 (en) | 2023-10-13 | 2025-11-11 | Spora Cayman Holdings Limited | Large-scale production of mycelium-based textiles at mushroom farm facilities |
| WO2026027251A1 (en) | 2024-08-01 | 2026-02-05 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Signal peptides for increased protein secretion |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6100042A (en) * | 1993-03-31 | 2000-08-08 | Cadus Pharmaceutical Corporation | Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor |
| US20030013154A1 (en) | 1998-02-24 | 2003-01-16 | Chiron Corporation | Pichia secretory leader for protein expression |
| WO2001077351A1 (en) | 2000-04-07 | 2001-10-18 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Vectors and methods for dual protein expression in pichia pastoris and escherichia coli |
| KR20030062854A (ko) | 2002-01-21 | 2003-07-28 | 주식회사 엘지생명과학 | 분비형 벡터를 이용한 효모에서의 재조합 단백질의 제조방법 |
| US7314974B2 (en) * | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
| AU2003250828A1 (en) | 2002-06-11 | 2003-12-22 | Glaxo Group Limited | Immunogenic compositions comprising a xenogenic prostate protein p501s |
| AR047440A1 (es) * | 2004-01-21 | 2006-01-18 | Novozymes As | Produccion de un anticuerpo monoclonal en un hongo heterocarion o una celula huesped fungal |
| US20070248967A1 (en) | 2005-06-09 | 2007-10-25 | National Institute Of Advanced Industrial Science | Reporter Assay Using Secrectory Luminescent Enzymes |
| KR20070009269A (ko) | 2005-07-15 | 2007-01-18 | 한국생명공학연구원 | 재조합단백질 생산용 단백질융합인자 라이브러리 및이로부터 획득된 단백질융합인자 |
| JP5354559B2 (ja) * | 2005-11-24 | 2013-11-27 | 独立行政法人産業技術総合研究所 | 高効率分泌シグナルペプチド及びそれらを利用したタンパク質発現系 |
| WO2008052043A2 (en) * | 2006-10-24 | 2008-05-02 | Cogenesys, Inc. | Opioid receptor agonist fusion proteins |
| US20110165681A1 (en) | 2009-02-26 | 2011-07-07 | Massachusetts Institute Of Technology | Light-Activated Proton Pumps and Applications Thereof |
| US8501449B2 (en) * | 2007-12-04 | 2013-08-06 | Proteon Therapeutics, Inc. | Recombinant elastase proteins and methods of manufacturing and use thereof |
| WO2010058057A1 (es) | 2008-11-21 | 2010-05-27 | Consejo Superior De Investigaciones Científicas (Csic) (90%) | Lacasas de alto potencial redox obtenidas por evolución dirigida |
| US8440456B2 (en) * | 2009-05-22 | 2013-05-14 | Vib, Vzw | Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins |
| EP2258855A1 (en) * | 2009-05-28 | 2010-12-08 | Universität für Bodenkultur Wien | Expression sequences |
| US8785159B2 (en) * | 2009-11-25 | 2014-07-22 | Alliance For Sustainable Energy, Llc | Extracellular secretion of recombinant proteins |
| WO2012060666A2 (ko) * | 2010-11-04 | 2012-05-10 | 한국생명공학연구원 | 효모에서 인체 상피세포 성장인자를 대량 생산하는 방법 |
| GB201105418D0 (en) | 2011-03-31 | 2011-05-18 | Univ Durham | Pesticide |
| EP2565262A1 (en) * | 2011-08-31 | 2013-03-06 | VTU Holding GmbH | Protein expression |
| US9732146B2 (en) | 2012-03-30 | 2017-08-15 | The United States Of America As Represented By The Department Of Veterans Affairs | Antibody-mediated transduction of heat shock proteins into living cells |
| WO2014066374A1 (en) | 2012-10-22 | 2014-05-01 | Refactored Materials, Inc. | Cellular reprogramming for product optimization |
| AU2013341049B2 (en) | 2012-10-29 | 2017-07-20 | Lonza Ltd | Expression sequences |
| CA2905180C (en) | 2013-03-15 | 2023-03-07 | Alder Biopharmaceuticals, Inc. | Temperature shift for high yield expression of polypeptides in yeast and other transformed cells |
| EP3046585B1 (en) * | 2013-09-17 | 2021-08-25 | Bolt Threads, Inc. | Methods and compositions for synthesizing improved silk fibers |
| JP2018501814A (ja) | 2014-11-11 | 2018-01-25 | クララ フーズ カンパニー | 卵白タンパク質産生のための方法および組成物 |
| KR102402443B1 (ko) | 2015-03-16 | 2022-05-30 | 볼트 쓰레즈, 인크. | 개선된 실크 섬유 |
| EP3307765B1 (en) | 2015-06-11 | 2024-04-10 | Bolt Threads, Inc. | Recombinant protein fiber yarns with improved properties |
| WO2018027131A1 (en) * | 2016-08-05 | 2018-02-08 | Cargill, Incorporated | Leader-modified glucoamylase polypeptides and engineered yeast strains having enhanced bioproduct production |
| KR20250121449A (ko) | 2017-03-10 | 2025-08-12 | 볼트 쓰레즈, 인크. | 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법 |
-
2018
- 2018-03-09 KR KR1020257025185A patent/KR20250121449A/ko active Pending
- 2018-03-09 KR KR1020237000420A patent/KR102618002B1/ko active Active
- 2018-03-09 KR KR1020237044072A patent/KR102840788B1/ko active Active
- 2018-03-09 KR KR1020197029638A patent/KR102486713B1/ko active Active
- 2018-03-09 EP EP18764964.5A patent/EP3592762A4/en active Pending
- 2018-03-09 JP JP2019548956A patent/JP7063486B2/ja active Active
- 2018-03-09 WO PCT/US2018/021817 patent/WO2018165594A1/en not_active Ceased
- 2018-03-13 US US15/920,331 patent/US10906947B2/en active Active
-
2020
- 2020-12-30 US US17/138,350 patent/US11370815B2/en active Active
-
2022
- 2022-03-07 JP JP2022034241A patent/JP2022078220A/ja active Pending
- 2022-05-23 US US17/751,277 patent/US12122810B2/en active Active
-
2024
- 2024-02-21 JP JP2024024860A patent/JP2024045697A/ja active Pending
- 2024-10-21 US US18/922,358 patent/US20250122252A1/en active Pending
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