|
FR2556219B1
(fr)
|
1983-12-07 |
1987-06-26 |
Merieux Inst |
Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines
|
|
US5426641A
(en)
|
1994-01-28 |
1995-06-20 |
Bell Communications Research, Inc. |
Adaptive class AB amplifier for TDMA wireless communications systems
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
WO1997047732A2
(en)
|
1996-06-14 |
1997-12-18 |
Smithkline Beecham Corporation |
Hexameric fusion proteins and uses therefor
|
|
US20090074839A1
(en)
|
1997-01-22 |
2009-03-19 |
Marton Milankovits |
Pharmaceutical Compositions Primarily for the Treatment and Prevention of Genitourinary Infections and their Extragenital Complications
|
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
EP2180054A1
(en)
|
1999-12-24 |
2010-04-28 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
US20050089932A1
(en)
|
2001-04-26 |
2005-04-28 |
Avidia Research Institute |
Novel proteins with targeted binding
|
|
EP1697520A2
(en)
|
2003-12-22 |
2006-09-06 |
Xencor, Inc. |
Fc polypeptides with novel fc ligand binding sites
|
|
KR101374454B1
(ko)
|
2005-03-31 |
2014-03-17 |
추가이 세이야쿠 가부시키가이샤 |
회합제어에 의한 폴리펩티드 제조방법
|
|
GB0614780D0
(en)
|
2006-07-25 |
2006-09-06 |
Ucb Sa |
Biological products
|
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
BRPI0620639A2
(pt)
|
2006-12-21 |
2011-11-22 |
Micromet Ag |
anticorpos de cadeia simples biespecìficos e composição farmacêutica compreendendo os mesmos
|
|
CA2682605A1
(en)
|
2007-04-18 |
2008-10-30 |
Zymogenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
KR20100021601A
(ko)
|
2007-05-14 |
2010-02-25 |
바이오겐 아이덱 엠에이 인코포레이티드 |
단일-쇄 Fc(ScFc) 부분, 이를 포함하는 결합 폴리펩타이드, 및 이에 관련된 방법
|
|
KR101580937B1
(ko)
|
2007-06-01 |
2015-12-31 |
유니버시티 오브 매릴랜드, 발티모어 |
면역글로불린 불변영역 Fc 수용체 결합제
|
|
AU2009204501B2
(en)
|
2008-01-07 |
2015-02-12 |
Amgen Inc. |
Method for making antibody Fc-heterodimeric molecules using electrostatic steering effects
|
|
CA2720368C
(en)
|
2008-04-02 |
2017-08-22 |
Macrogenics, Inc. |
Her2/neu-specific antibodies and methods of using same
|
|
WO2010042481A1
(en)
|
2008-10-06 |
2010-04-15 |
University Of Chicago |
Compositions and methods related to bacterial eap, emp, and/or adsa proteins
|
|
WO2010065578A2
(en)
|
2008-12-04 |
2010-06-10 |
Leukosight Inc. |
POLYPEPTIDES COMPRISING Fc FRAGMENTS OF IMMUNOGLOBULIN G (IgG) AND METHODS OF USING THE SAME
|
|
US10865233B2
(en)
*
|
2008-12-18 |
2020-12-15 |
Dana-Farber Cancer Institute, Inc. |
NKG2D-fc for immunotherapy
|
|
BRPI1006998A2
(pt)
|
2009-01-23 |
2015-08-25 |
Biogen Idec Inc |
Polipeptídeos fc estabilizados com função efetora reduzida e métodos de uso
|
|
US8858948B2
(en)
|
2009-05-20 |
2014-10-14 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
|
EP2432451A2
(en)
|
2009-05-20 |
2012-03-28 |
Children's Medical Center Corporation |
Compositions for the treatment of metastatic cancer and methods of use thereof
|
|
CN102549016B
(zh)
|
2009-06-30 |
2015-05-06 |
研究发展基金会 |
免疫球蛋白fc多肽
|
|
NZ598962A
(en)
|
2009-09-16 |
2014-12-24 |
Genentech Inc |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
PT2486141T
(pt)
|
2009-10-07 |
2018-05-09 |
Macrogenics Inc |
Polipéptidos contendo uma região fc que apresenta uma função efectora melhorada, devido a modificações do grau de fucosilação, e métodos para a sua utilização
|
|
CA2781539C
(en)
|
2009-11-23 |
2021-07-20 |
Amgen Inc. |
Monomeric antibody fc
|
|
GB0922209D0
(en)
|
2009-12-18 |
2010-02-03 |
Univ Nottingham |
Proteins, nucleic acid molecules and compositions
|
|
CA2800173C
(en)
|
2010-05-21 |
2019-05-14 |
Ulrik Nielsen |
Bi-specific fusion proteins
|
|
DK2591099T3
(da)
|
2010-07-09 |
2021-02-15 |
Bioverativ Therapeutics Inc |
Kimære koagulationsfaktorer
|
|
AU2011282579B2
(en)
|
2010-07-28 |
2014-10-23 |
Gliknik Inc. |
Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin Fc compositions
|
|
JP2013537416A
(ja)
|
2010-08-13 |
2013-10-03 |
メディミューン リミテッド |
変異型Fc領域を含むモノマーポリペプチド及び使用方法
|
|
AU2011325833C1
(en)
|
2010-11-05 |
2017-07-13 |
Zymeworks Bc Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
|
IN2013MN01438A
(enExample)
|
2011-03-17 |
2015-06-12 |
Univ Ramot |
|
|
NZ608724A
(en)
|
2011-03-25 |
2015-12-24 |
Glenmark Pharmaceuticals Sa |
Hetero-dimeric immunoglobulins
|
|
AU2013270682A1
(en)
|
2012-06-08 |
2014-12-11 |
Biogen Ma Inc. |
Procoagulant compounds
|
|
CA2877363A1
(en)
|
2012-06-21 |
2013-12-27 |
Indiana University Research And Technology Corporation |
Incretin receptor ligand polypeptide fc-region fusion polypeptides and conjugates with altered fc-effector function
|
|
MX2015002269A
(es)
|
2012-08-20 |
2015-07-06 |
Gliknik Inc |
Moleculas con actividad de union al antigeno y al receptor fc gamma polivalente.
|
|
BR112015008663B1
(pt)
|
2012-10-17 |
2021-01-12 |
CSL Behring Lengnau AG |
Uso de uma quantidade eficaz de uma proteína polimérica compreendendo seis unidades demonômero de polipeptídeo
|
|
CN104558194B
(zh)
|
2013-10-17 |
2018-04-27 |
泰州迈博太科药业有限公司 |
一类抗CD20-Flex双功能融合蛋白、其制备方法及用途
|
|
JP2016538283A
(ja)
*
|
2013-11-13 |
2016-12-08 |
ザイムワークス,インコーポレイテッド |
Egfr及び/またはher2を標的にする一価抗原結合性構築物及びその使用
|
|
WO2015095684A1
(en)
|
2013-12-20 |
2015-06-25 |
Indiana University Research And Technology Corporation |
Lipidated incretin receptor ligand human immunoglobulin fc-region fusion polypeptides
|
|
BR112016016411A2
(pt)
*
|
2014-01-15 |
2017-10-03 |
Hoffmann La Roche |
VARIANTES DE REGIÕES-"Fc" COM PROPRIEDADES DE LIGAÇÃO DE "FcRn" MODIFICADAS
|
|
EP3094647A1
(en)
*
|
2014-01-15 |
2016-11-23 |
F. Hoffmann-La Roche AG |
Fc-region variants with modified fcrn- and maintained protein a-binding properties
|
|
AU2015226101B2
(en)
|
2014-03-05 |
2019-08-22 |
Ucb Biopharma Sprl |
Multimeric Fc proteins
|
|
TW201619188A
(zh)
|
2014-03-05 |
2016-06-01 |
優稀美生物醫藥公司 |
多聚體Fc蛋白質
|
|
JP2017513481A
(ja)
|
2014-04-16 |
2017-06-01 |
ユーシービー バイオファルマ エスピーアールエル |
多量体Fcタンパク質
|
|
AU2015252866B2
(en)
*
|
2014-05-02 |
2021-01-28 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered Fc constructs
|
|
NZ726514A
(en)
|
2014-05-29 |
2019-01-25 |
Macrogenics Inc |
Tri-specific binding molecules and methods of use thereof
|
|
EP3423572B1
(en)
|
2016-03-02 |
2023-11-29 |
Momenta Pharmaceuticals, Inc. |
Methods related to engineered fc constructs
|
|
US11623964B2
(en)
|
2016-05-23 |
2023-04-11 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered Fc constructs
|
|
US11220531B2
(en)
|
2017-01-06 |
2022-01-11 |
Janssen Biotech, Inc. |
Engineered Fc constructs
|