JP2020502228A5 - - Google Patents
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- JP2020502228A5 JP2020502228A5 JP2019534154A JP2019534154A JP2020502228A5 JP 2020502228 A5 JP2020502228 A5 JP 2020502228A5 JP 2019534154 A JP2019534154 A JP 2019534154A JP 2019534154 A JP2019534154 A JP 2019534154A JP 2020502228 A5 JP2020502228 A5 JP 2020502228A5
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- JP
- Japan
- Prior art keywords
- compound
- solvent
- formula
- reaction mixture
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023016009A JP2023052918A (ja) | 2016-12-23 | 2023-02-06 | ５－［［４－［２－［５－（１－ヒドロキシエチル）－２－ピリジニル］エトキシ］フェニル］メチル］－２，４－チアゾリジンジオンおよびその塩を調製するためのプロセス |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382648 | 2016-12-23 | ||
| EP16382648.0 | 2016-12-23 | ||
| PCT/IB2017/058374 WO2018116281A1 (en) | 2016-12-23 | 2017-12-22 | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023016009A Division JP2023052918A (ja) | 2016-12-23 | 2023-02-06 | ５－［［４－［２－［５－（１－ヒドロキシエチル）－２－ピリジニル］エトキシ］フェニル］メチル］－２，４－チアゾリジンジオンおよびその塩を調製するためのプロセス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020502228A JP2020502228A (ja) | 2020-01-23 |
| JP2020502228A5 true JP2020502228A5 (https=) | 2021-02-12 |
| JP7294661B2 JP7294661B2 (ja) | 2023-06-20 |
Family
ID=57799523
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019534154A Active JP7294661B2 (ja) | 2016-12-23 | 2017-12-22 | ５－［［４－［２－［５－（１－ヒドロキシエチル）－２－ピリジニル］エトキシ］フェニル］メチル］－２，４－チアゾリジンジオンおよびその塩を調製するためのプロセス |
| JP2023016009A Withdrawn JP2023052918A (ja) | 2016-12-23 | 2023-02-06 | ５－［［４－［２－［５－（１－ヒドロキシエチル）－２－ピリジニル］エトキシ］フェニル］メチル］－２，４－チアゾリジンジオンおよびその塩を調製するためのプロセス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023016009A Withdrawn JP2023052918A (ja) | 2016-12-23 | 2023-02-06 | ５－［［４－［２－［５－（１－ヒドロキシエチル）－２－ピリジニル］エトキシ］フェニル］メチル］－２，４－チアゾリジンジオンおよびその塩を調製するためのプロセス |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11124505B2 (https=) |
| EP (1) | EP3559010B1 (https=) |
| JP (2) | JP7294661B2 (https=) |
| KR (1) | KR102609373B1 (https=) |
| CN (1) | CN110198945B (https=) |
| BR (1) | BR112019012972B1 (https=) |
| CA (1) | CA3046744A1 (https=) |
| CY (1) | CY1125531T1 (https=) |
| DK (1) | DK3559010T3 (https=) |
| ES (1) | ES2926580T3 (https=) |
| HR (1) | HRP20221067T1 (https=) |
| HU (1) | HUE059604T2 (https=) |
| IL (1) | IL267557B (https=) |
| LT (1) | LT3559010T (https=) |
| MX (1) | MX379709B (https=) |
| PL (1) | PL3559010T3 (https=) |
| PT (1) | PT3559010T (https=) |
| SI (1) | SI3559010T1 (https=) |
| WO (1) | WO2018116281A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2926580T3 (es) | 2016-12-23 | 2022-10-27 | Minoryx Therapeutics S L | Proceso para preparar 5-[[4-[2-[5-(1-hidroxietil)-2-piridinil]etoxi]fenil]metil]-2,4-tiazolidindiona y sales de la misma |
| CN112823004A (zh) | 2018-06-06 | 2021-05-18 | 米尼奥尔克斯治疗有限公司 | 5-[[4-[2-[5-乙酰基吡啶-2-基]乙氧基]苄基]-1,3-噻唑烷-2,4-二酮及其盐的用途 |
| EP3801515B1 (en) | 2018-06-06 | 2025-04-09 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione and its salts for use in the treatment of mitochondrial diseases |
| CN112512524A (zh) | 2018-06-06 | 2021-03-16 | 米尼奥尔克斯治疗有限公司 | 给予治疗有效量的5-[[4-[2-[5-(1-羟基乙基)吡啶-2-基]乙氧基]苯基]甲基]-1,3-噻唑烷-2,4-二酮的方法 |
| EP4642456A1 (en) | 2022-12-28 | 2025-11-05 | Minoryx Therapeutics S.L. | Optimized dosing of leriglitazone |
| WO2024231881A2 (en) | 2023-05-09 | 2024-11-14 | Minoryx Therapeutics S.L. | Polymorphic forms and formulations of leriglitazone |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69231886T2 (de) * | 1991-04-11 | 2002-03-28 | Pharmacia & Upjohn Co., Kalamazoo | Thiazolidindionderivate, herstellung und anwendung |
| US5952509A (en) | 1996-06-27 | 1999-09-14 | Takeda Chemical Industries, Ltd. | Production of benzaldehyde compounds |
| US6067749A (en) | 1996-07-11 | 2000-05-30 | Tasmanian Alkaloids Pty. Ltd. | Papaver somniferum strain with high concentration of thebaine and oripavine |
| US5869669A (en) | 1996-07-26 | 1999-02-09 | Penick Corporation | Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
| HUP0304096A2 (hu) | 2003-12-19 | 2005-08-29 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás pioglitazon hidrogénklorid előállítására és intermedierjei |
| GB0421687D0 (en) | 2004-09-30 | 2004-11-03 | Johnson Matthey Plc | Preparation of opiate analgesics |
| CA2594666A1 (en) | 2005-02-16 | 2006-08-24 | Micromet Ag | Use of activated polymers for separation of protein and polypeptide multimers |
| US20090247560A1 (en) * | 2006-09-28 | 2009-10-01 | Banyu Pharmaceutical Co., Ltd. | Diaryl ketimine derivative |
| JPWO2008136428A1 (ja) * | 2007-04-27 | 2010-07-29 | 武田薬品工業株式会社 | 含窒素５員複素環化合物 |
| EP2855489B1 (en) * | 2012-04-26 | 2017-01-04 | Bristol-Myers Squibb Company | Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
| WO2014152843A1 (en) | 2013-03-14 | 2014-09-25 | Deuterx, Llc | Deuterium-enriched 2,4-thiazolidinediones and methods of treatment |
| EA202091120A3 (ru) | 2014-04-02 | 2020-12-30 | Минорикс Терапьютикс С.Л. | Производные 2,4-тиазолинидона в лечении расстройств центральной нервной системы |
| ES2926580T3 (es) | 2016-12-23 | 2022-10-27 | Minoryx Therapeutics S L | Proceso para preparar 5-[[4-[2-[5-(1-hidroxietil)-2-piridinil]etoxi]fenil]metil]-2,4-tiazolidindiona y sales de la misma |
-
2017
- 2017-12-22 ES ES17829042T patent/ES2926580T3/es active Active
- 2017-12-22 SI SI201731203T patent/SI3559010T1/sl unknown
- 2017-12-22 HR HRP20221067TT patent/HRP20221067T1/hr unknown
- 2017-12-22 BR BR112019012972-3A patent/BR112019012972B1/pt active IP Right Grant
- 2017-12-22 EP EP17829042.5A patent/EP3559010B1/en active Active
- 2017-12-22 HU HUE17829042A patent/HUE059604T2/hu unknown
- 2017-12-22 US US16/470,866 patent/US11124505B2/en active Active
- 2017-12-22 KR KR1020197021529A patent/KR102609373B1/ko active Active
- 2017-12-22 WO PCT/IB2017/058374 patent/WO2018116281A1/en not_active Ceased
- 2017-12-22 PL PL17829042.5T patent/PL3559010T3/pl unknown
- 2017-12-22 JP JP2019534154A patent/JP7294661B2/ja active Active
- 2017-12-22 DK DK17829042.5T patent/DK3559010T3/da active
- 2017-12-22 LT LTEPPCT/IB2017/058374T patent/LT3559010T/lt unknown
- 2017-12-22 MX MX2019007327A patent/MX379709B/es unknown
- 2017-12-22 PT PT178290425T patent/PT3559010T/pt unknown
- 2017-12-22 CN CN201780084302.3A patent/CN110198945B/zh active Active
- 2017-12-22 CA CA3046744A patent/CA3046744A1/en active Pending
-
2019
- 2019-06-20 IL IL267557A patent/IL267557B/en unknown
-
2021
- 2021-09-20 US US17/479,838 patent/US11731963B2/en active Active
-
2022
- 2022-09-06 CY CY20221100593T patent/CY1125531T1/el unknown
-
2023
- 2023-02-06 JP JP2023016009A patent/JP2023052918A/ja not_active Withdrawn
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