JP2020063241A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020063241A5 JP2020063241A5 JP2019185670A JP2019185670A JP2020063241A5 JP 2020063241 A5 JP2020063241 A5 JP 2020063241A5 JP 2019185670 A JP2019185670 A JP 2019185670A JP 2019185670 A JP2019185670 A JP 2019185670A JP 2020063241 A5 JP2020063241 A5 JP 2020063241A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- linker
- tate
- targeting moiety
- conjugate according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021131359A JP2021175757A (ja) | 2014-06-30 | 2021-08-11 | 標的化コンジュゲートならびにその粒子及び製剤 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462019001P | 2014-06-30 | 2014-06-30 | |
| US62/019,001 | 2014-06-30 | ||
| US201462077487P | 2014-11-10 | 2014-11-10 | |
| US62/077,487 | 2014-11-10 | ||
| US201562150413P | 2015-04-21 | 2015-04-21 | |
| US62/150,413 | 2015-04-21 | ||
| JP2017500064A JP6602834B2 (ja) | 2014-06-30 | 2015-06-30 | 標的化コンジュゲートならびにその粒子及び製剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500064A Division JP6602834B2 (ja) | 2014-06-30 | 2015-06-30 | 標的化コンジュゲートならびにその粒子及び製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021131359A Division JP2021175757A (ja) | 2014-06-30 | 2021-08-11 | 標的化コンジュゲートならびにその粒子及び製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020063241A JP2020063241A (ja) | 2020-04-23 |
| JP2020063241A5 true JP2020063241A5 (https=) | 2020-06-11 |
| JP6932389B2 JP6932389B2 (ja) | 2021-09-08 |
Family
ID=55020088
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500064A Expired - Fee Related JP6602834B2 (ja) | 2014-06-30 | 2015-06-30 | 標的化コンジュゲートならびにその粒子及び製剤 |
| JP2019185670A Expired - Fee Related JP6932389B2 (ja) | 2014-06-30 | 2019-10-09 | 標的化コンジュゲートならびにその粒子及び製剤 |
| JP2021131359A Pending JP2021175757A (ja) | 2014-06-30 | 2021-08-11 | 標的化コンジュゲートならびにその粒子及び製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500064A Expired - Fee Related JP6602834B2 (ja) | 2014-06-30 | 2015-06-30 | 標的化コンジュゲートならびにその粒子及び製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021131359A Pending JP2021175757A (ja) | 2014-06-30 | 2021-08-11 | 標的化コンジュゲートならびにその粒子及び製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US9750818B2 (https=) |
| EP (1) | EP3160518A4 (https=) |
| JP (3) | JP6602834B2 (https=) |
| KR (2) | KR102062025B1 (https=) |
| CN (2) | CN106573077B (https=) |
| AU (2) | AU2015284236B2 (https=) |
| BR (1) | BR212016030926U2 (https=) |
| CA (1) | CA2953371C (https=) |
| IL (1) | IL249647B (https=) |
| MX (1) | MX379365B (https=) |
| PH (1) | PH12017500023A1 (https=) |
| RU (1) | RU2695220C2 (https=) |
| SG (1) | SG11201610880RA (https=) |
| WO (1) | WO2016004048A2 (https=) |
| ZA (1) | ZA201608432B (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190015350A1 (en) | 2013-02-05 | 2019-01-17 | Anp Technologies, Inc. | Nanoparticles Containing a Taxane and their Use |
| US9533054B2 (en) * | 2013-03-11 | 2017-01-03 | Shanghai Jiao Tong University | Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof |
| MX379365B (es) | 2014-06-30 | 2025-03-11 | Tarveda Therapeutics Inc | Conjugados y partículas direccionados y formulaciones de estos. |
| WO2017003940A1 (en) * | 2015-06-30 | 2017-01-05 | Tarveda Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
| BR112018000217A2 (pt) * | 2015-07-15 | 2018-09-04 | Celator Pharmaceuticals Inc | sistemas de distribuição de nanopartículas aperfeiçoados |
| US11160871B2 (en) | 2015-10-28 | 2021-11-02 | Tarveda Therapeutics, Inc. | SSTR-targeted conjugates and particles and formulations thereof |
| RU2736590C2 (ru) | 2016-02-16 | 2020-11-18 | Стронгбридж Даблин Лимитед | Велдореотид, обладающий плохой растворимостью в физиологических условиях, для применения при лечении акромегалии, акромегалии со злокачественным новообразованием, экспрессирующих sst-r5 опухолей, диабета 2 типа, гипергликемии и опухолей, связанных с гормонами |
| WO2017161096A1 (en) * | 2016-03-16 | 2017-09-21 | Tarveda Therapeutics, Inc. | Antibody mimic conjugates and particles |
| EP3442592A4 (en) * | 2016-04-13 | 2019-11-27 | Tarveda Therapeutics, Inc. | NEUROTENSIN RECEPTOR BINDING CONJUGATES AND FORMULATIONS THEREOF |
| WO2017210246A2 (en) * | 2016-05-31 | 2017-12-07 | Tarveda Therapeutics, Inc. | Penicillamine conjugates and particles and formulations thereof |
| WO2018041942A1 (en) | 2016-08-31 | 2018-03-08 | Biolog Life Science Institute Forschungslabor Und Biochemica-Vertrieb Gmbh | New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates |
| CN109890423A (zh) * | 2016-10-28 | 2019-06-14 | 塔弗达治疗有限公司 | Sstr靶向缀合物及其颗粒和制剂 |
| WO2018222987A1 (en) * | 2017-06-01 | 2018-12-06 | Tarveda Therapeutics, Inc. | Targeted constructs |
| CA3069159A1 (en) * | 2017-07-11 | 2019-01-17 | Sustained Nano Systems Llc | Hypercompressed pharmaceutical formulations |
| CN107422021B (zh) * | 2017-07-14 | 2019-11-19 | 北京朗阅科技有限公司 | 琼脂糖胶囊及其制备方法与应用 |
| CA3073604A1 (en) * | 2017-08-25 | 2019-02-28 | Nal Pharmaceutical Group Limited | Compositions and methods of delivery of pharmacological agents |
| CA3078776A1 (en) * | 2017-10-27 | 2019-05-02 | Tarveda Therapeutics, Inc. | Sstr-targeted conjugates and formulations thereof |
| WO2019118830A1 (en) * | 2017-12-14 | 2019-06-20 | Tarveda Therapeutics, Inc. | Hsp90-targeting conjugates and formulations thereof |
| EP3801506A4 (en) * | 2018-06-01 | 2022-08-10 | Tva (Abc), Llc | POLYTHERAPY |
| CN109124096B (zh) * | 2018-08-23 | 2021-08-06 | 广州百隆威尔精密五金制品有限公司 | 一种升降橱柜 |
| BR112021005320A2 (pt) * | 2018-12-17 | 2021-06-15 | Remegen Co., Ltd. | ligante para conjugados de anticorpo-fármaco e seu uso |
| WO2020191011A1 (en) * | 2019-03-18 | 2020-09-24 | The Trustees Of Columbia University In The City Of New York | Non-hydrolyzable, non-cleavable, stable linkers for precision therapeutics and uses thereof |
| CN109848440A (zh) * | 2019-04-10 | 2019-06-07 | 燕山大学 | 一种钯纳米立方体的制备方法 |
| CA3143373A1 (en) * | 2019-06-25 | 2020-12-30 | Tarveda Therapeutics, Inc. | Sstr-targeted conjugates and formulations thereof |
| CN119236187A (zh) | 2020-02-21 | 2025-01-03 | 吉益医疗公司 | 聚合物包封的药物颗粒 |
| CN112250647A (zh) * | 2020-06-30 | 2021-01-22 | 浙江大学 | 紫杉烷类药物前体、制备方法和应用 |
| US11571481B2 (en) | 2020-12-21 | 2023-02-07 | Cornell University | Peptide-linked drug delivery system |
| WO2022174171A1 (en) | 2021-02-15 | 2022-08-18 | Anp Technologies, Inc. | Pharmaceutical composition containing taxane nanoaggregates and use thereof |
| TW202302073A (zh) * | 2021-03-18 | 2023-01-16 | 予宇生技股份有限公司 | 包含帶電脂質的脂質製劑的組合物及製備方法 |
| JP2024512659A (ja) * | 2021-04-01 | 2024-03-19 | アール.ピー.シェーラー テクノロジーズ,エルエルシー | 医薬製剤におけるアニオン性キレート剤としてのリン脂質 |
| IT202100014330A1 (it) * | 2021-06-01 | 2022-12-01 | The Ubeauty Com Llc | Prodotto per la cura della pelle e procedimento per la sua realizzazione. |
| CN118005545B (zh) * | 2024-01-04 | 2025-02-18 | 兰州大学 | 小分子抗菌肽模拟物及其应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US5702717A (en) * | 1995-10-25 | 1997-12-30 | Macromed, Inc. | Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers |
| US5843903A (en) * | 1995-11-27 | 1998-12-01 | The Administrators Of The Tulane Educational Fund | Targeted cytotoxic anthracycline analogs |
| AT405906B (de) | 1997-03-14 | 1999-12-27 | Irene Dr Virgolini | Radiomarkierte somatostatin rezeptor-liganden zur diagnose und therapie |
| US6358491B1 (en) * | 1999-08-27 | 2002-03-19 | Berlex Laboratories, Inc. | Somatostatin analogs |
| WO2001032218A1 (en) * | 1999-11-01 | 2001-05-10 | University Technology Corporation | Compositions and methods for controlled-release delivery and increased potency of pharmaceuticals via hydrophobic ion-pairing |
| AU4267700A (en) * | 2000-01-13 | 2001-07-19 | Academia Sinica | Application of somatostatin analogs to specific delivery of anti-tumor drugs into tumor cells |
| DE10006572A1 (de) * | 2000-02-14 | 2001-08-23 | Deutsches Krebsforsch | Oligonucleotid-Konjugate |
| FR2824563B1 (fr) * | 2001-05-10 | 2004-12-03 | Bio Merieux | Particules composites, conjugues derives, procede de preparation et applications |
| US6441163B1 (en) * | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| US8877901B2 (en) * | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| EP1531846A4 (en) | 2002-02-27 | 2006-04-19 | Us Gov Health & Human Serv | Conjugates of ligand, linker and cytotoxic agent and related compositions and methods of use |
| US7771727B2 (en) | 2002-03-01 | 2010-08-10 | The Administrators Of The Tulane Educational Fund | Conjugates of therapeutic or cytotoxic agents and biologically active peptides |
| ES2377318T3 (es) * | 2002-09-06 | 2012-03-26 | Cerulean Pharma Inc. | Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos |
| TWI260228B (en) * | 2002-12-31 | 2006-08-21 | Ind Tech Res Inst | Delivery carrier of presenting cell of somatostatin receptor |
| CA2523605A1 (en) | 2003-03-10 | 2004-09-23 | Charles W. Spangler | Targeted agents for both photodiagnosis and photodynamic therapy |
| CN101791409A (zh) * | 2003-04-22 | 2010-08-04 | 研究及应用科学协会股份有限公司 | 肽载体 |
| US8088387B2 (en) * | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| US7276497B2 (en) | 2003-05-20 | 2007-10-02 | Immunogen Inc. | Cytotoxic agents comprising new maytansinoids |
| MXPA05011811A (es) * | 2003-05-20 | 2006-02-17 | Immunogen Inc | Agentes citotoxicos mejorados que comprenden nuevos maitansinoides. |
| JP4318985B2 (ja) * | 2003-08-21 | 2009-08-26 | 日本メジフィジックス株式会社 | ソマトスタチンアナログ誘導体およびその利用 |
| ES2503719T3 (es) * | 2005-02-11 | 2014-10-07 | Immunogen, Inc. | Procedimiento para preparar conjugados de anticuerpos y de maitansinoides |
| CA3000520C (en) | 2005-08-24 | 2023-04-04 | Immunogen, Inc. | Process for preparing antibody maytansinoid conjugates |
| EP2354163A3 (en) | 2005-09-26 | 2013-04-24 | Medarex, Inc. | Conjugates of duocarmycin and anti-CD70 or anti-PSMA antibodies |
| EP1864682A1 (en) * | 2006-06-09 | 2007-12-12 | Sanofi-Aventis | Leptomycin derivatives |
| US10925977B2 (en) * | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
| TW200831129A (en) * | 2006-10-06 | 2008-08-01 | Amgen Inc | Stable formulations |
| DK2644194T3 (en) | 2008-03-18 | 2017-07-03 | Genentech Inc | Combinations of an anti-HER2 antibody-drug conjugate and docetaxel |
| SG189817A1 (en) | 2008-04-30 | 2013-05-31 | Immunogen Inc | Potent conjugates and hydrophilic linkers |
| JP2011519894A (ja) * | 2008-05-06 | 2011-07-14 | グラクソ グループ リミテッド | 生物活性薬の封入 |
| KR101324804B1 (ko) * | 2008-05-13 | 2013-11-01 | 아이알엠 엘엘씨 | 키나제 억제제로서의 질소 함유 융합 헤테로사이클 및 그의 조성물 |
| WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| FR2945211A1 (fr) * | 2009-05-06 | 2010-11-12 | Sanofi Aventis | Combinaison antitumorale comprenant la cabazitaxel et la capecitabine |
| DK3223013T3 (en) * | 2009-07-02 | 2019-04-15 | Sloan Kettering Inst Cancer Res | FLUORESCING SILICA-BASED NANOPARTICLES |
| EP2518086A1 (en) | 2009-12-25 | 2012-10-31 | Riken | Radiolabeled compound directable in vivo to target tissue and use thereof |
| MX2012012383A (es) * | 2010-04-30 | 2012-11-30 | Sanwa Kagaku Kenkyusho Co | Peptido para mejorar la bioestabilidad de una sustancia bioactica y sustancia bioactiva que tiene bioestabilidad mejorada. |
| TW201302793A (zh) * | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| CA2810838C (en) * | 2010-09-08 | 2021-07-06 | The Board Of Regents Of The University Of Texas System | Somatostatin receptor-based cancer therapy |
| AU2012223364A1 (en) * | 2011-03-01 | 2013-09-19 | Ge Healthcare Limited | Radiolabelled Octreotate analogues as PET tracers |
| WO2012138911A2 (en) * | 2011-04-05 | 2012-10-11 | The Administrators Of The Tulane Educational Fund | Conjugates of anti-hiv drugs and somatostatin analogs |
| WO2012145112A2 (en) | 2011-04-18 | 2012-10-26 | Immunogen, Inc. | Novel maytansinoid derivatives with sulfoxide linker |
| CA2836338C (en) * | 2011-05-16 | 2022-05-03 | Koninklijke Philips N.V. | Tetrazine derivatives used in bio-orthogonal drug activation |
| JP6209159B2 (ja) | 2011-06-21 | 2017-10-04 | イミュノジェン・インコーポレーテッド | ペプチドリンカーを有する新規メイタンシノイド誘導体およびその結合体 |
| JP6355563B2 (ja) * | 2012-02-27 | 2018-07-11 | アムニクス オペレーティング インコーポレイテッド | Xten共役組成物およびそれを製造する方法 |
| EP2895146A1 (en) * | 2012-09-17 | 2015-07-22 | BIND Therapeutics, Inc. | Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same |
| EP3566750A3 (en) | 2013-02-28 | 2020-04-08 | ImmunoGen, Inc. | Conjugates comprising cell-binding agents and cytotoxic agents |
| CN105814083A (zh) | 2013-10-15 | 2016-07-27 | 加州生物医学研究所 | 嵌合抗原受体t细胞开关和其用途 |
| MX379365B (es) * | 2014-06-30 | 2025-03-11 | Tarveda Therapeutics Inc | Conjugados y partículas direccionados y formulaciones de estos. |
-
2015
- 2015-06-30 MX MX2017000080A patent/MX379365B/es unknown
- 2015-06-30 AU AU2015284236A patent/AU2015284236B2/en not_active Ceased
- 2015-06-30 CN CN201580044836.4A patent/CN106573077B/zh not_active Expired - Fee Related
- 2015-06-30 JP JP2017500064A patent/JP6602834B2/ja not_active Expired - Fee Related
- 2015-06-30 SG SG11201610880RA patent/SG11201610880RA/en unknown
- 2015-06-30 RU RU2016151859A patent/RU2695220C2/ru active
- 2015-06-30 KR KR1020177002414A patent/KR102062025B1/ko not_active Expired - Fee Related
- 2015-06-30 CN CN201910762952.XA patent/CN110478495A/zh active Pending
- 2015-06-30 WO PCT/US2015/038569 patent/WO2016004048A2/en not_active Ceased
- 2015-06-30 EP EP15815040.9A patent/EP3160518A4/en not_active Withdrawn
- 2015-06-30 KR KR1020197037860A patent/KR20190143491A/ko not_active Withdrawn
- 2015-06-30 CA CA2953371A patent/CA2953371C/en active Active
- 2015-06-30 BR BR212016030926U patent/BR212016030926U2/pt active IP Right Grant
-
2016
- 2016-12-07 ZA ZA2016/08432A patent/ZA201608432B/en unknown
- 2016-12-16 US US15/382,487 patent/US9750818B2/en not_active Expired - Fee Related
- 2016-12-19 IL IL249647A patent/IL249647B/en active IP Right Grant
-
2017
- 2017-01-03 PH PH12017500023A patent/PH12017500023A1/en unknown
- 2017-07-18 US US15/652,957 patent/US10322191B2/en not_active Expired - Fee Related
- 2017-07-18 US US15/652,947 patent/US10624967B2/en not_active Expired - Fee Related
-
2018
- 2018-06-07 AU AU2018204037A patent/AU2018204037B2/en not_active Ceased
-
2019
- 2019-10-09 JP JP2019185670A patent/JP6932389B2/ja not_active Expired - Fee Related
-
2020
- 2020-02-18 US US16/793,094 patent/US11458206B2/en active Active
-
2021
- 2021-08-11 JP JP2021131359A patent/JP2021175757A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020063241A5 (https=) | ||
| JP6092867B2 (ja) | 担体連結しているトレプロスチニルプロドラッグ | |
| CN108164474B (zh) | 作为免疫调节剂的1,2,4-二唑衍生物 | |
| US9096642B2 (en) | Therapeutic compounds for immunomodulation | |
| JP7483776B2 (ja) | 放出制御pth化合物の漸増用量設定 | |
| JP2020514300A5 (https=) | ||
| RU2548905C2 (ru) | Терапевтические пептиды | |
| CN103874480A (zh) | 前列环素的缓释组合物 | |
| EP1480657A1 (en) | Polymers for delivering peptides and small molecules i in vivo /i | |
| JPWO1999061061A1 (ja) | 薬物複合体 | |
| JP2010521485A5 (https=) | ||
| RU2007131504A (ru) | Пептиды, обладающие агонистической активностью в отношении рецептора нейропептида-2-(y2r) | |
| WO2011042453A1 (en) | Subcutaneous paliperidone composition | |
| US11077082B2 (en) | Composition and method for dual targeting in treatment of neuroendocrine tumors | |
| US20170014524A1 (en) | Auristatin-antibody conjugates and uses thereof | |
| US8518891B2 (en) | Chemotherapeutic conjugates and methods of use | |
| KR101828613B1 (ko) | 올리고머-칼슘 모방체 컨쥬게이트 및 관련 화합물 | |
| SK150196A3 (en) | Peptides with immunomodulatory effects, pharmaceutical formulations containing them and their use | |
| WO2020205996A2 (en) | Locally acting toll-like receptor 7 (tlr7) and/or tlr8 agonist immunotherapy compounds and their uses | |
| JP7339285B2 (ja) | Tlr7ペプチドコンジュゲート | |
| EP1372733B1 (en) | Pharmaceutical compositions of active polypeptides for enhanced pharmacological activity through oral and parenteral administration | |
| US20220362278A1 (en) | Renal targeting-type drug delivery carrier having excellent biodegrability | |
| US11351137B2 (en) | Composition and method for dual targeting in treatment of neuroendocrine tumors | |
| KR20170091610A (ko) | 신규 peg 유도체 | |
| RU2789198C2 (ru) | Композиция и способ двойного нацеливания при лечении нейроэндокринных опухолей |