JP2020039342A5 - - Google Patents
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- Publication number
- JP2020039342A5 JP2020039342A5 JP2019195276A JP2019195276A JP2020039342A5 JP 2020039342 A5 JP2020039342 A5 JP 2020039342A5 JP 2019195276 A JP2019195276 A JP 2019195276A JP 2019195276 A JP2019195276 A JP 2019195276A JP 2020039342 A5 JP2020039342 A5 JP 2020039342A5
- Authority
- JP
- Japan
- Prior art keywords
- cfh
- medical device
- functional sequence
- recombinant protein
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000016550 Complement Factor H Human genes 0.000 claims 20
- 108010053085 Complement Factor H Proteins 0.000 claims 20
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 9
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 9
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 102000034356 gene-regulatory proteins Human genes 0.000 claims 2
- 108091006104 gene-regulatory proteins Proteins 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000003094 microcapsule Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 230000000399 orthopedic effect Effects 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021195598A JP7320585B2 (ja) | 2013-10-14 | 2021-12-01 | 診断的および治療的使用を有するタンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1318170.6A GB201318170D0 (en) | 2013-10-14 | 2013-10-14 | Proteins with Diagnostic and Therapeutic Uses |
| GB1318170.6 | 2013-10-14 | ||
| JP2016522745A JP6691042B2 (ja) | 2013-10-14 | 2014-10-13 | 診断的および治療的使用を有するタンパク質 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016522745A Division JP6691042B2 (ja) | 2013-10-14 | 2014-10-13 | 診断的および治療的使用を有するタンパク質 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021195598A Division JP7320585B2 (ja) | 2013-10-14 | 2021-12-01 | 診断的および治療的使用を有するタンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020039342A JP2020039342A (ja) | 2020-03-19 |
| JP2020039342A5 true JP2020039342A5 (https=) | 2020-04-30 |
| JP6987825B2 JP6987825B2 (ja) | 2022-01-05 |
Family
ID=49680023
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016522745A Active JP6691042B2 (ja) | 2013-10-14 | 2014-10-13 | 診断的および治療的使用を有するタンパク質 |
| JP2019195276A Active JP6987825B2 (ja) | 2013-10-14 | 2019-10-28 | 診断的および治療的使用を有するタンパク質 |
| JP2021195598A Active JP7320585B2 (ja) | 2013-10-14 | 2021-12-01 | 診断的および治療的使用を有するタンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016522745A Active JP6691042B2 (ja) | 2013-10-14 | 2014-10-13 | 診断的および治療的使用を有するタンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021195598A Active JP7320585B2 (ja) | 2013-10-14 | 2021-12-01 | 診断的および治療的使用を有するタンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US10035827B2 (https=) |
| EP (2) | EP3757115B1 (https=) |
| JP (3) | JP6691042B2 (https=) |
| CN (3) | CN114031676A (https=) |
| AU (3) | AU2014335925B2 (https=) |
| BR (1) | BR112016008055A2 (https=) |
| CA (1) | CA2925663A1 (https=) |
| DK (1) | DK3057979T3 (https=) |
| ES (2) | ES3037618T3 (https=) |
| GB (1) | GB201318170D0 (https=) |
| WO (1) | WO2015055991A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017075189A1 (en) * | 2015-10-27 | 2017-05-04 | University Of Massachusetts | Factor h-fc immunotherapy |
| WO2017114401A1 (zh) * | 2015-12-31 | 2017-07-06 | 江苏匡亚生物医药科技有限公司 | 具有补体调节活性的重组补体因子h-免疫球蛋白融合蛋白及其制备方法与应用 |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| AR122286A1 (es) * | 2019-07-17 | 2022-08-31 | Gemini Therapeutics Sub Inc | Anticuerpos potenciadores del factor h y usos de estos |
| AU2021293174A1 (en) | 2020-06-14 | 2023-01-19 | Vertex Pharmaceuticals Incorporated | Complement Factor I-related compositions and methods |
| EP4001301A1 (en) * | 2020-11-13 | 2022-05-25 | Navigo Proteins Gmbh | Binding protein for complement factor h (cfh) |
| GB202102931D0 (en) | 2021-03-02 | 2021-04-14 | Invizius Ltd | Peritoneal fluid composition |
| GB202202728D0 (en) | 2022-02-28 | 2022-04-13 | Invizius Ltd | Peritoneal fluid composition |
| EP4706639A1 (en) | 2024-09-06 | 2026-03-11 | Invizius Limited | Complement binding fusion protein |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| CH680045A5 (https=) * | 1990-02-16 | 1992-06-15 | Om Lab Sa | |
| US6592876B1 (en) * | 1993-04-20 | 2003-07-15 | Uab Research Foundation | Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products |
| EP0885965A3 (en) * | 1997-06-20 | 2000-01-12 | Smithkline Beecham Corporation | Histidine kinase polypeptides |
| US6858706B2 (en) * | 1998-04-07 | 2005-02-22 | St. Jude Children's Research Hospital | Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof |
| DE69942176D1 (de) * | 1998-04-07 | 2010-05-06 | Medimmune Llc | Choline-bindende proteine derivate aus pneumokoken als impfstoff |
| US20010016200A1 (en) * | 1998-04-23 | 2001-08-23 | Briles David E. | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
| JP2002516251A (ja) * | 1998-04-23 | 2002-06-04 | ユーエイビー リサーチ ファンデーション | 肺炎球菌表面プロテインＣ（ＰｓｐＣ）のエピトープ領域およびその菌株選択、ならびにそのための使用法 |
| GB9816337D0 (en) * | 1998-07-27 | 1998-09-23 | Cortecs Uk Ltd | Proteins |
| MXPA01011279A (es) | 1999-05-07 | 2002-07-02 | Genentech Inc | Tratamiento de enfermedades autoinmunes con antagonistas que se unene a los marcadores de superficie, de celulas b. |
| JP2003519089A (ja) * | 1999-06-10 | 2003-06-17 | ユーエイビー リサーチ ファウンデーション | 肺炎球菌表面型蛋白質配合ワクチン |
| EP1301602A2 (en) * | 2000-07-20 | 2003-04-16 | Hansa Medical AB | Fh-binding protein of streptococcus pneumoniae |
| AU2001287645A1 (en) * | 2000-07-20 | 2002-02-05 | Hansa Medical Ab | Fh-binding protein of streptococcus pneumiae |
| US6957392B2 (en) * | 2002-01-16 | 2005-10-18 | Laszlo Systems, Inc. | Interface engine providing a continuous user interface |
| DE10258924A1 (de) * | 2002-12-17 | 2004-07-08 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Mit die Adhäsion von biologischem Material vermittelnden Substanzen beschichtete Vorrichtung |
| US8105612B2 (en) * | 2005-05-13 | 2012-01-31 | Novartis Vaccines And Diagnostics, Inc. | Serum resistance factors of gram positive bacteria |
| ES2369372T3 (es) * | 2006-04-05 | 2011-11-30 | Abb Technology Ag | Actuador electromagnético , en particular para un interruptor de media tensión. |
| DE102010001914A1 (de) * | 2010-02-15 | 2011-08-18 | Robert Bosch GmbH, 70469 | Lenkvorrichtung für ein Kraftfahrzeug |
| WO2012072769A1 (en) * | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| EP2655400B1 (en) * | 2010-12-20 | 2015-09-02 | The Trustees Of The University Of Pennsylvania | Factor h binding peptides and uses thereof |
| US9181308B2 (en) * | 2011-03-28 | 2015-11-10 | St. Jude Children's Research Hospital | Methods and compositions employing immunogenic fusion proteins |
| WO2015025856A1 (ja) | 2013-08-21 | 2015-02-26 | 国立大学法人大阪大学 | 標的物質とリガンドとの結合親和性を測定するための方法、ならびに該方法に使用するための試薬助剤およびキット |
-
2013
- 2013-10-14 GB GBGB1318170.6A patent/GB201318170D0/en not_active Ceased
-
2014
- 2014-10-13 WO PCT/GB2014/053072 patent/WO2015055991A1/en not_active Ceased
- 2014-10-13 CA CA2925663A patent/CA2925663A1/en active Pending
- 2014-10-13 ES ES20176131T patent/ES3037618T3/es active Active
- 2014-10-13 JP JP2016522745A patent/JP6691042B2/ja active Active
- 2014-10-13 EP EP20176131.9A patent/EP3757115B1/en active Active
- 2014-10-13 BR BR112016008055A patent/BR112016008055A2/pt not_active Application Discontinuation
- 2014-10-13 EP EP14789350.7A patent/EP3057979B1/en active Active
- 2014-10-13 US US15/029,399 patent/US10035827B2/en active Active
- 2014-10-13 CN CN202110888802.0A patent/CN114031676A/zh active Pending
- 2014-10-13 DK DK14789350.7T patent/DK3057979T3/da active
- 2014-10-13 ES ES14789350T patent/ES2800599T3/es active Active
- 2014-10-13 CN CN201480056203.0A patent/CN105764918B/zh active Active
- 2014-10-13 CN CN202110888795.4A patent/CN114028538A/zh active Pending
- 2014-10-13 AU AU2014335925A patent/AU2014335925B2/en active Active
-
2018
- 2018-07-06 US US16/028,740 patent/US10774116B2/en active Active
-
2019
- 2019-03-15 AU AU2019201829A patent/AU2019201829B2/en active Active
- 2019-10-28 JP JP2019195276A patent/JP6987825B2/ja active Active
-
2020
- 2020-08-17 US US16/995,344 patent/US20210017239A1/en not_active Abandoned
- 2020-11-25 AU AU2020277188A patent/AU2020277188B2/en active Active
-
2021
- 2021-09-24 US US17/483,920 patent/US20220009974A1/en not_active Abandoned
- 2021-12-01 JP JP2021195598A patent/JP7320585B2/ja active Active
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