|
DE3382562D1
(de)
|
1982-09-24 |
1992-06-25 |
Us Health |
Wiederherstellung von gewebe bei tieren.
|
|
NZ210699A
(en)
|
1984-01-04 |
1989-06-28 |
Int Genetic Eng |
Isolation of an osteogenic protein of the p3 immunologically related family
|
|
EP0169016B2
(en)
|
1984-07-16 |
2004-04-28 |
Celtrix Pharmaceuticals, Inc. |
Polypeptide cartilage-inducing factors found in bone
|
|
WO1987005330A1
(en)
|
1986-03-07 |
1987-09-11 |
Michel Louis Eugene Bergh |
Method for enhancing glycoprotein stability
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
US20050186593A1
(en)
*
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
NZ306767A
(en)
|
1995-04-11 |
2000-03-27 |
Univ Johns Hopkins |
Method of identifying molecular interactions employing counterselection and at least two hybrid molecules or two hybrid systems
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
ES2320603T3
(es)
|
1997-07-30 |
2009-05-25 |
Emory University |
Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
|
|
MXPA01007366A
(es)
|
1999-01-21 |
2002-06-04 |
Metamorphix Inc |
Inhibidores de factores de crecimiento y diferenciacion y usos de los mismos.
|
|
EP3006039B1
(en)
|
2004-03-02 |
2021-01-06 |
Acceleron Pharma Inc. |
Alk7 polypeptides for use in promoting fat loss
|
|
JP2008507288A
(ja)
|
2004-07-23 |
2008-03-13 |
アクセルロン ファーマ インコーポレーテッド |
ActRII受容体ポリペプチド、方法、および組成物
|
|
JP2009541275A
(ja)
|
2006-06-22 |
2009-11-26 |
ノボ・ノルデイスク・エー/エス |
二重特異性抗体の生産
|
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
|
CN104524548A
(zh)
|
2006-12-18 |
2015-04-22 |
阿塞勒隆制药公司 |
活化素-actrii拮抗剂及在提高红细胞水平中的用途
|
|
TW201803890A
(zh)
*
|
2007-02-02 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
|
JP6157046B2
(ja)
*
|
2008-01-07 |
2017-07-05 |
アムジェン インコーポレイテッド |
静電的ステアリング(electrostaticsteering)効果を用いた抗体Fcヘテロ二量体分子を作製するための方法
|
|
JP5719766B2
(ja)
|
2008-05-02 |
2015-05-20 |
アクセルロン ファーマ, インコーポレイテッド |
血管新生および周皮細胞組成物を調節するための方法および組成物
|
|
DK2318028T3
(da)
|
2008-06-26 |
2020-05-04 |
Acceleron Pharma Inc |
Antagonister af opløselig activin-aktriia og anvendelser til øgning af røde blodcelleniveauer
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
TW201803586A
(zh)
|
2008-08-14 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
使用gdf阱以增加紅血球水平
|
|
AU2010204985A1
(en)
|
2009-01-13 |
2011-08-04 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
|
JP5755635B2
(ja)
|
2009-03-30 |
2015-07-29 |
アクセルロン ファーマ, インコーポレイテッド |
Bmp−alk3アンタゴニストおよび骨成長促進のためのその使用
|
|
KR20180026795A
(ko)
*
|
2009-06-12 |
2018-03-13 |
악셀레론 파마 인코포레이티드 |
절두된 ActRIIB-FC 융합 단백질
|
|
AU2010282361B2
(en)
|
2009-08-13 |
2015-03-19 |
Acceleron Pharma Inc. |
Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels
|
|
EP3202459B1
(en)
|
2009-09-09 |
2021-04-14 |
Acceleron Pharma Inc. |
Actriib antagonists and dosing and uses thereof for treating obesity or type 2 diabetes by regulating body fat content
|
|
EP2478013B1
(en)
|
2009-09-16 |
2018-10-24 |
F.Hoffmann-La Roche Ag |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
|
CN102850458B
(zh)
|
2011-06-28 |
2014-10-01 |
华博生物医药技术(上海)有限公司 |
新型重组双功能融合蛋白及其制法和用途
|
|
KR20140084211A
(ko)
|
2011-10-17 |
2014-07-04 |
악셀레론 파마 인코포레이티드 |
효과가 없는 적혈구생성 치료를 위한 방법 및 조성물
|
|
WO2013063536A1
(en)
|
2011-10-27 |
2013-05-02 |
Acceleron Pharma, Inc. |
Actriib binding agents and uses thereof
|
|
HK1225740A1
(zh)
|
2013-08-22 |
2017-09-15 |
Acceleron Pharma Inc. |
TGF-β受体II型变体及其用途
|
|
JP2017509647A
(ja)
*
|
2014-03-21 |
2017-04-06 |
アクセルロン ファーマ, インコーポレイテッド |
アクチビンbおよび/またはgdf11の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法
|
|
EP3808778A1
(en)
*
|
2014-04-18 |
2021-04-21 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
CN114699529A
(zh)
|
2014-06-13 |
2022-07-05 |
阿塞勒隆制药公司 |
用于治疗溃疡的方法和组合物
|
|
JP2018501307A
(ja)
|
2014-12-03 |
2018-01-18 |
セルジーン コーポレイション |
アクチビン−ActRIIアンタゴニスト及び貧血を治療するための使用
|
|
US10358476B2
(en)
|
2015-04-06 |
2019-07-23 |
Acceleron Pharma Inc. |
Single arm type I and type II receptor fusion proteins and uses thereof
|
|
MA41920B1
(fr)
|
2015-04-06 |
2021-05-31 |
Acceleron Pharma Inc |
Protéines de fusion de récepteur type i et type ii à bras unique et leurs utilisations
|
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
|
CA2983440C
(en)
|
2015-04-22 |
2024-03-12 |
Alivegen Usa Inc. |
Novel hybrid actriib ligand trap proteins for treating muscle wasting diseases
|
|
WO2016205370A1
(en)
|
2015-06-15 |
2016-12-22 |
Santa Maria Biotherapeutics, Inc. |
Methods of using activin receptor iib-based proteins
|
|
US20200231652A1
(en)
|
2015-08-31 |
2020-07-23 |
National Research Council Of Canada |
Tgf-b-receptor ectodomain fusion molecules and uses thereof
|
|
WO2017177013A1
(en)
|
2016-04-06 |
2017-10-12 |
Acceleron Pharma Inc. |
Alk7 antagonists and uses thereof
|
|
CA3029890A1
(en)
|
2016-07-07 |
2018-01-11 |
Acceleron Pharma Inc. |
Tgf-beta superfamily heteromultimers and uses thereof
|
|
CA3039573A1
(en)
|
2016-10-05 |
2018-04-12 |
Acceleron Pharma Inc. |
Alk4:actriib heteromultimers and uses thereof
|
|
AU2017338915B2
(en)
|
2016-10-05 |
2024-11-21 |
Acceleron Pharma Inc. |
TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof
|
|
CN110036025B
(zh)
|
2016-10-05 |
2024-03-22 |
阿塞勒隆制药公司 |
变体ActRIIB蛋白及其用途
|
|
JOP20190085A1
(ar)
|
2016-10-20 |
2019-04-17 |
Biogen Ma Inc |
طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة
|
|
NZ754161A
(en)
|
2016-11-10 |
2025-11-28 |
Keros Therapeutics Inc |
Activin receptor type iia variants and methods of use thereof
|