JP2019531093A5 - - Google Patents
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- Publication number
- JP2019531093A5 JP2019531093A5 JP2019536693A JP2019536693A JP2019531093A5 JP 2019531093 A5 JP2019531093 A5 JP 2019531093A5 JP 2019536693 A JP2019536693 A JP 2019536693A JP 2019536693 A JP2019536693 A JP 2019536693A JP 2019531093 A5 JP2019531093 A5 JP 2019531093A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- amino acid
- acid sequence
- seq
- her2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16190221 | 2016-09-22 | ||
| EP16190221.8 | 2016-09-22 | ||
| PCT/EP2017/073768 WO2018054971A1 (en) | 2016-09-22 | 2017-09-20 | Recombinant binding proteins and their use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019531093A JP2019531093A (ja) | 2019-10-31 |
| JP2019531093A5 true JP2019531093A5 (OSRAM) | 2020-05-21 |
| JP6976335B2 JP6976335B2 (ja) | 2021-12-08 |
Family
ID=57046984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019536693A Expired - Fee Related JP6976335B2 (ja) | 2016-09-22 | 2017-09-20 | 組み換え結合タンパク質及びその使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10717772B2 (OSRAM) |
| EP (1) | EP3515933B9 (OSRAM) |
| JP (1) | JP6976335B2 (OSRAM) |
| KR (1) | KR102270315B1 (OSRAM) |
| CN (1) | CN109790206A (OSRAM) |
| AR (1) | AR109680A1 (OSRAM) |
| AU (1) | AU2017331329B2 (OSRAM) |
| BR (1) | BR112019005587A2 (OSRAM) |
| CA (1) | CA3036301C (OSRAM) |
| CL (1) | CL2019000729A1 (OSRAM) |
| CO (1) | CO2019002609A2 (OSRAM) |
| ES (1) | ES2953516T3 (OSRAM) |
| IL (1) | IL265489B (OSRAM) |
| MX (1) | MX377424B (OSRAM) |
| MY (1) | MY196882A (OSRAM) |
| NZ (1) | NZ751689A (OSRAM) |
| PH (1) | PH12019500596B1 (OSRAM) |
| SA (1) | SA519401369B1 (OSRAM) |
| WO (1) | WO2018054971A1 (OSRAM) |
| ZA (1) | ZA201901592B (OSRAM) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021014649A (es) | 2019-06-04 | 2022-01-06 | Molecular Partners Ag | Dominio de repetición de anquirina diseñado con estabilidad mejorada. |
| EP3980045A1 (en) * | 2019-06-04 | 2022-04-13 | Molecular Partners AG | Recombinant fap binding proteins and their use |
| CA3139051A1 (en) * | 2019-06-04 | 2020-12-10 | Christian REICHEN | Multispecific proteins |
| JP2022535107A (ja) * | 2019-06-04 | 2022-08-04 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 組換え４－１ｂｂ結合タンパク質及びそれらの使用 |
| CN115003689A (zh) | 2019-12-11 | 2022-09-02 | 分子合作伙伴股份公司 | 具有改变的表面残基的经设计的锚蛋白重复结构域 |
| MX2022013945A (es) | 2020-05-06 | 2023-02-14 | Molecular Partners Ag | Nuevas proteinas de union a repeticiones de anquirina y sus usos. |
| BR112022023049A2 (pt) | 2020-05-14 | 2022-12-20 | Molecular Partners Ag | Proteínas multiespecíficas |
| JP2023528207A (ja) * | 2020-05-14 | 2023-07-04 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 組換えｃｄ４０結合タンパク質及びそれらの使用 |
| CA3202358A1 (en) | 2020-12-16 | 2022-06-23 | Andreas BOSSHART | Novel slow-release prodrugs |
| WO2022190008A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Protease cleavable prodrugs |
| CA3211248A1 (en) | 2021-03-09 | 2022-09-15 | Nina RESCHKE | Novel darpin based cd33 engagers |
| CA3211368A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Novel darpin based cd123 engagers |
| EP4304731A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Novel darpin based multi-specific t-cell engagers |
| AU2022413461A1 (en) | 2021-12-14 | 2024-06-06 | Molecular Partners Ag | Designed repeat domains with dual binding specificity and their use |
| IL318514A (en) | 2022-08-01 | 2025-03-01 | Molecular Partners Ag | Loading and using modified re-designed websites |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
| TW202448926A (zh) | 2023-02-17 | 2024-12-16 | 比利時商艾伯霖克斯公司 | 結合新生兒fc受體之多肽 |
| WO2024179981A1 (en) | 2023-02-27 | 2024-09-06 | Molecular Partners Ag | Darpins for use in reducing renal accumulation of drugs |
| WO2024251628A1 (en) | 2023-06-06 | 2024-12-12 | Molecular Partners Ag | Recombinant cd16a binding proteins and their use |
| WO2024251742A1 (en) | 2023-06-06 | 2024-12-12 | Molecular Partners Ag | Recombinant cd2 binding proteins and their use |
| WO2025146487A1 (en) | 2024-01-05 | 2025-07-10 | Molecular Partners Ag | Multispecific binding proteins |
| WO2025146491A1 (en) | 2024-01-05 | 2025-07-10 | Molecular Partners Ag | Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent |
| WO2025163144A1 (en) | 2024-01-31 | 2025-08-07 | Molecular Partners Ag | Recombinant mesothelin binding proteins and their use |
| WO2025181039A1 (en) | 2024-03-01 | 2025-09-04 | Molecular Partners Ag | Therapeutic combinations comprising a multi-specific t cell engager |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
| EP1332209B1 (en) | 2000-09-08 | 2009-11-11 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| DK1567641T3 (da) * | 2001-08-24 | 2012-08-27 | Uvic Industry Partnerships Inc | Proaerolysin indeholdende proteaseaktiveringssekvenser og fremgangsmåder til anvendelse til behandling af prostatacancer. |
| NZ581958A (en) | 2004-11-12 | 2011-01-28 | Bayer Schering Pharma Ag | Recombinant newcastle disease virus comprising a transgene encoding a prodrug-converting enzyme or protease for use in the treatment of cancer |
| AU2006268780B2 (en) | 2005-07-08 | 2011-03-24 | University Of Zurich | Phage display using cotranslational translocation of fusion polypeptides |
| JP2010539915A (ja) | 2007-09-24 | 2010-12-24 | ユニバーシティ・オブ・チューリッヒ | 設計されたアルマジロリピートタンパク質 |
| CN101970490A (zh) | 2007-11-27 | 2011-02-09 | 埃博灵克斯股份有限公司 | 针对异二聚体细胞因子和/或其受体的氨基酸序列以及包括所述氨基酸序列的多肽 |
| RU2550258C2 (ru) | 2008-11-03 | 2015-05-10 | Молекьюлар Партнерс Аг | Связывающие белки, ингибирующие взаимодействия vegf-a рецептора |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| US9221892B2 (en) | 2010-11-26 | 2015-12-29 | Molecular Partners Ag | Capping modules for designed ankyrin repeat proteins |
| EA201391607A1 (ru) | 2011-04-29 | 2014-04-30 | Янссен Байотек, Инк. | Связывающие il4/il13 белки с повторами и их применение |
| RU2014150224A (ru) | 2012-06-28 | 2016-08-20 | Молекьюлар Партнерс Аг | Сконструированный белок с анкириновым повтором, связывающийся с фактором роста тромбоцитов |
| JP2015532306A (ja) * | 2012-10-15 | 2015-11-09 | チューリッヒ大学 | 癌治療のための二重特異性ｈｅｒ２リガンド |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP6486908B2 (ja) | 2013-05-31 | 2019-03-20 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 肝細胞増殖因子に結合する設計アンキリン反復タンパク質 |
| RU2769470C2 (ru) | 2015-04-02 | 2022-04-01 | Молекьюлар Партнерс Аг | Рекомбинантные связывающие белки и их применение |
-
2017
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja not_active Expired - Fee Related
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt not_active Application Discontinuation
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es not_active Application Discontinuation
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en not_active IP Right Cessation
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en not_active Ceased
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 PH PH1/2019/500596A patent/PH12019500596B1/en unknown
- 2017-09-20 MX MX2019003298A patent/MX377424B/es active IP Right Grant
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en not_active Ceased
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko not_active Expired - Fee Related
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
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