JP2019530729A5 - - Google Patents

Info

Publication number

JP2019530729A5

JP2019530729A5 JP2019520647A JP2019520647A JP2019530729A5 JP 2019530729 A5 JP2019530729 A5 JP 2019530729A5 JP 2019520647 A JP2019520647 A JP 2019520647A JP 2019520647 A JP2019520647 A JP 2019520647A JP 2019530729 A5 JP2019530729 A5 JP 2019530729A5

Authority

JP

Japan

Prior art keywords

composition according

liposome

phospholipid

composition

topical

Prior art date

2017-10-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000000203 mixture Substances 0.000 claims 22
• 239000002502 liposome Substances 0.000 claims 10
• 150000003904 phospholipids Chemical class 0.000 claims 6
• 230000000699 topical effect Effects 0.000 claims 5
• RZZPDXZPRHQOCG-OJAKKHQRSA-M CDP-choline(1-) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-M 0.000 claims 4
• 229960000686 benzalkonium chloride Drugs 0.000 claims 4
• CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 4
• 229960001284 citicoline Drugs 0.000 claims 4
• 239000002674 ointment Substances 0.000 claims 4
• 208000010412 Glaucoma Diseases 0.000 claims 3
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
• REYJJPSVUYRZGE-UHFFFAOYSA-N Octadecylamine Chemical compound CCCCCCCCCCCCCCCCCCN REYJJPSVUYRZGE-UHFFFAOYSA-N 0.000 claims 2
• 239000004480 active ingredient Substances 0.000 claims 2
• 229940030600 antihypertensive agent Drugs 0.000 claims 2
• 239000002220 antihypertensive agent Substances 0.000 claims 2
• 239000006071 cream Substances 0.000 claims 2
• 239000003889 eye drop Substances 0.000 claims 2
• 239000006260 foam Substances 0.000 claims 2
• 229920002674 hyaluronan Polymers 0.000 claims 2
• 229960003160 hyaluronic acid Drugs 0.000 claims 2
• 150000003839 salts Chemical class 0.000 claims 2
• 239000000243 solution Substances 0.000 claims 2
• 239000007921 spray Substances 0.000 claims 2
• 239000000725 suspension Substances 0.000 claims 2
• 229940079593 drug Drugs 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1