EA201990752A1 - Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы - Google Patents

Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы

Info

Publication number
EA201990752A1
EA201990752A1 EA201990752A EA201990752A EA201990752A1 EA 201990752 A1 EA201990752 A1 EA 201990752A1 EA 201990752 A EA201990752 A EA 201990752A EA 201990752 A EA201990752 A EA 201990752A EA 201990752 A1 EA201990752 A1 EA 201990752A1
Authority
EA
Eurasian Patent Office
Prior art keywords
glaucoma
treatment
composition containing
citycoline
liposoma
Prior art date
Application number
EA201990752A
Other languages
English (en)
Russian (ru)
Inventor
Кристиано Вирно
Марко Малициа
Original Assignee
Омикрон Италиа С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Омикрон Италиа С.Р.Л. filed Critical Омикрон Италиа С.Р.Л.
Publication of EA201990752A1 publication Critical patent/EA201990752A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201990752A 2016-10-17 2017-10-16 Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы EA201990752A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102016000103956A IT201600103956A1 (it) 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma
PCT/IB2017/056400 WO2018073720A1 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma

Publications (1)

Publication Number Publication Date
EA201990752A1 true EA201990752A1 (ru) 2019-09-30

Family

ID=58010202

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201990752A EA201990752A1 (ru) 2016-10-17 2017-10-16 Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы

Country Status (9)

Country Link
US (1) US10576039B2 (enExample)
EP (1) EP3525758B1 (enExample)
JP (1) JP7042262B2 (enExample)
EA (1) EA201990752A1 (enExample)
ES (1) ES2987910T3 (enExample)
IT (1) IT201600103956A1 (enExample)
MX (1) MX388927B (enExample)
TN (1) TN2019000112A1 (enExample)
WO (1) WO2018073720A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4717257A1 (de) 2017-06-09 2026-04-01 Omnivision GmbH Zusammensetzung zur behandlung des trockenen auges
IT201800005309A1 (it) * 2018-05-11 2019-11-11 Composizione ad attivita’ antimicrobica
CN110559261A (zh) * 2018-06-06 2019-12-13 常州药物研究所有限公司 含有纳米交联透明质酸的脂质体微乳及其制备方法和应用
CN111840220B (zh) * 2020-08-19 2022-09-30 开封康诺药业有限公司 一种胞磷胆碱钠注射液及其制备方法
WO2022238833A1 (en) * 2021-05-10 2022-11-17 Omikron Italia S.R.L. Oral solution based on citicoline and nicotinamide for use in the treatment of glaucoma
WO2025037323A1 (en) * 2023-08-12 2025-02-20 Pavan Kumar Kothapuvari Pharmaceutical compositions for treatment of dry eye disease and associated disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
JPWO2002034252A1 (ja) * 2000-10-26 2004-03-04 千寿製薬株式会社 ジペプチジルアルデヒド誘導体含有医薬組成物
WO2010092597A2 (en) * 2009-02-11 2010-08-19 Lyka Labs Limited Liposomal citicoline injection
IT1398378B1 (it) * 2010-02-22 2013-02-22 Omikron Italia S R L Citicolina per il trattamento del glaucoma e dell'ipertensione oculare.
FR2961694B1 (fr) * 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
SG187770A1 (en) * 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
CN102078299B (zh) * 2011-01-04 2012-09-26 海南美大制药有限公司 胞磷胆碱钠脂质体固体制剂

Also Published As

Publication number Publication date
EP3525758B1 (en) 2024-05-22
JP7042262B2 (ja) 2022-03-25
EP3525758A1 (en) 2019-08-21
MX2019004463A (es) 2019-09-11
EP3525758C0 (en) 2024-05-22
US10576039B2 (en) 2020-03-03
MX388927B (es) 2025-03-20
ES2987910T3 (es) 2024-11-18
IT201600103956A1 (it) 2018-04-17
US20190321292A1 (en) 2019-10-24
TN2019000112A1 (en) 2020-10-05
JP2019530729A (ja) 2019-10-24
WO2018073720A1 (en) 2018-04-26

Similar Documents

Publication Publication Date Title
EA201990752A1 (ru) Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы
EA201790889A1 (ru) Офтальмологический раствор
IL282624A (en) Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders
BR112018012876A2 (pt) bisturi oftálmico e métodos de uso
HK1258588A1 (zh) 用於治疗眼科疾病的化合物和制剂
IL281773B2 (en) Ophthalmic preparation for the treatment of dry eye disease
MX2019001276A (es) Viriones de virus adenoasociados con cápside variante y métodos para su uso.
EA201892431A1 (ru) Олигонуклеотиды для лечения заболевания глаз
EA201890725A1 (ru) Агонисты фарнезоидного х-рецептора и их применение
MX2020003534A (es) Composiciones oftalmicas que comprenden latanoprost para usarse en el tratamiento de las enfermedades oculares.
MX360683B (es) Sensibilizantes de (bacterio) clorofila para el tratamiento de enfermedades y transtornos oculares campo tecnico.
EA201490721A1 (ru) Лекарственное средство для лечения заболеваний передней камеры глаза, включающее ребамипид и агент, удерживающий слезы
EA202091020A1 (ru) Замещенные имидазопиридинамиды и их применение
MX2020012011A (es) Conjugados y derivados de prostaglandina para tratar el glaucoma y la hipertension ocular.
EA202090966A1 (ru) МОНОКЛОНАЛЬНЫЕ АНТИ-TrkB АНТИТЕЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
NZ746468A (en) Methods of treating ocular conditions
EA201692402A1 (ru) Лекарственные формы для местного применения и их использование
EA202092069A1 (ru) Композиции и способы лечения макулярной дистрофии
CY1124538T1 (el) Χρηση prg4 για τη βελτιωση της δυναμικης οπτικης οξυτητας και εκτροπων υψηλοτερης ταξης
EA202192183A1 (ru) Композиции, обладающие активностью удаления липофусцина из клеток сетчатки
MX2016016090A (es) Composicion oftalmica para el tratamiento de infeccion ocular.
CY1111384T1 (el) Διαμορφωση των επιπεδων εκφρασης toy trpv
CO2019012336A2 (es) Métodos y composiciones para tratar enfermedades asociadas a la retina mediante inhibidores de ccr3
EA201800565A1 (ru) Композиция для лечения заболеваний уха, содержащая (+)-азасетрон
CL2020001426A1 (es) Composición tópica oftálmica que comprende ácido dobesilico para tratar enfermedades del segmento posterior del ojo.